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| 1 | Targeting EGFR and sonic hedgehog pathways for locally advanced eyelid and periocular carcinomas显示文摘For patients with metastatic or locally advanced eyelid and periocular carcinoma not amenable to surgical excision, targeted therapies have shown efficacy with better tolerability compared to cytotoxic chemotherapy. Overexpression of epithelial growth factor receptor was found in squamous cell carcinomas. Vismodegib targets the mutation in the hedgehog pathway identified in basal cell carcinoma and basal cell nevus syndrome. Targeted therapies provide a novel and potentially effective treatment alternative for patients with eyelid carcinoma not amendable for surgery, including those with metastatic, locally advanced disease, advanced age, and significant comorbidities. High cost, need for long-term treatment, and toxicity are relative limitations. | Vivian T Yin Helen Merritt Bita Esmaeli | 2014 | World Journal of Clinical Cases2014，2，9： | 2 |
| 2 | Heavy Metal Cation Retention by Unconventional Sorbents(Red Muds and Fly Ashes)显示文摘 | Resat Apak Esma Tütem Mehmet Hügül | 1998 | Wat Res1998，32，2： | 1 |
| 3 | The effects of dexmedetomidine on hemodynamic responses to tracheal intubation in hypertensive patients:A comparison with esmolol and sufentanyl显示文摘 | Hale YU Esma T Müge T | 2012 | J Res Med Sci2012，17，1： | 1 |
| 4 | Spectrophotometric determination of gallium (Ⅲ) with carminic acid and hexadecylpyridinium ehloride显示文摘 | HAYATI F ESMA T RESAT A | 1998 | Mikrochim Acta1998，129，12： | 1 |
| 5 | Adsorptive removal of chlorophenols from water by bituminous shale 显示文摘 | ESMA T RESAT A CAGATAY F U | 1998 | Water Res1998，32，8： | 1 |
| 6 | The effects of dexmedetomidine on hemodynamic responses to tracheal intubation in hypertensive pa- tients : A comparison with esmolol and sufentanyl 显示文摘 | Hale YU Esma T Mtige T | 2012 | J Res Med Sci2012，17，1： | 1 |
| 7 | Centri-voltammetric dopamine detection显示文摘 | SINAN C S ESMA S YUDUM T | 2014 | RSC Advances2014，4，31： | 1 |
| 8 | Adsorptive removal of chlorophenols from water by bituminous shale显示文摘 | Resat Apak Ca(G)atay F(u)nal 1998 | 1998 | Wat Res1998，32，： | 1 |
| 9 | Second derivative spectrophotometric method for simultaneous determination of cobalt,nickel and iron using 2-(5-bromo-2-pyridylazo)-5-diethylaminophe显示文摘 | Sozgen Kevser Tütem Esma | 2004 | Talanta2004，62，5： | 1 |
| 10 | Novel insights regarding the role of noncoding RNAs in diabetes显示文摘Diabetes mellitus(DM)is a group of metabolic disorders defined by hyperglycemia induced by insulin resistance,inadequate insulin secretion,or excessive glucagon secretion.In 2021,the global prevalence of diabetes is anticipated to be 10.7%(537 million people).Noncoding RNAs(ncRNAs)appear to have an important role in the initiation and progression of DM,according to a growing body of research.The two major groups of ncRNAs implicated in diabetic disorders are miRNAs and long noncoding RNAs.miRNAs are singlestranded,short(17–25 nucleotides),ncRNAs that influence gene expression at the post-transcriptional level.Because DM has reached epidemic proportions worldwide,it appears that novel diagnostic and therapeutic strategies are required to identify and treat complications associated with these diseases efficiently.miRNAs are gaining attention as biomarkers for DM diagnosis and potential treatment due to their function in maintaining physiological homeostasis via gene expression regulation.In this review,we address the issue of the gradually expanding global prevalence of DM by presenting a complete and upto-date synopsis of various regulatory miRNAs involved in these disorders.We hope this review will spark discussion about ncRNAs as prognostic biomarkers and therapeutic tools for DM.We examine and synthesize recent research that used novel,high-throughput technologies to uncover ncRNAs involved in DM,necessitating a systematic approach to examining and summarizing their roles and possible diagnostic and therapeutic uses. | Mirjana T Macvanin Zoran Gluvic Vladan Bajic Esma R Isenovic | 2023 | World Journal of Diabetes2023，14，7： | 0 |
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