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| 1 | Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations显示文摘 | Campagnolo E R Johnson K R Karpati A Rubin C S Kolpin D W Meyer M T Esteban J E Currier R W Smith K Thu K M McGeehin M | | 0，，： | 1 |
| 2 | Comparison of doxorubicin-eluting bead transarterial chemoembolization (DEB-TACE) with conventional transarterial chemoembolization (TACE) for the treatment of hepatocellular carcinoma显示文摘 | Ferrer Puchol M D la Parra C Esteban E | 2011 | Radiologia2011，53，3： | 1 |
| 3 | Integrative Food-grade Expression System Based on the Lactose Regulon of Lactobacillus casei显示文摘 | GOSALBES M J ESTEBAN C D GALAN J L | 2000 | Applied and Environmental Microbiology2000，66，11： | 1 |
| 4 | Laboratory characterization of shale properties显示文摘 | JOSH M ESTEBAN L PIANE C D | 2012 | Journal of Petrole- um Science Engineering2012，88，157： | 1 |
| 5 | Microtomographic study of the evolution of microstructure during creep of an AlSi12CuMgNi alloy reinforced with Al2O3 short fibres显示文摘 | GUILLERM C REQUNA A PETER D ESTEBAN D M ELODIE B | 2008 | Mater Sci Eng A2008，487，： | 1 |
| 6 | Integrative food- grade expression system based on the lactose regulon of Lacto bacillus easel 显示文摘 | Gosalbes M J Esteban C D Galan J L | 2000 | Appl Environ Microbiol2000，66，11： | 1 |
| 7 | Integrative foodgrade expression system based on the lactose regulon of Lactobacillus casei显示文摘 | GOSALBES M J ESTEBAN C D GAL? N J L | 2000 | Appl Environ Microbiol2000，66，11： | 1 |
| 8 | Integrative food-grade expression system based on the lactose regulon of lactobacillus casei显示文摘 | GOSALBES M J ESTEBAN C D GALAN J L | 2000 | Appl Environ Microbiol2000，66，11： | 1 |
| 9 | Steam reforming of Naph- thalene on Ni-Cr/Al2O3 Catalysts Doped with MgO,TiO2 ,and La2O3 显示文摘 | BANGALA D ABATZOGOLOU N ESTEBAN C | 1998 | AICHE1998，44，4： | 1 |
| 10 | Study of the mass sensitivity of SH-APM sensors with Maple V显示文摘 | ESTEBAN DEJOUS C REBIERE D | 1999 | Sensors and Actuators A: Physical1999，76，13： | 1 |
| 11 | Integrative food-grade expression system based on the lactose regulon of Lactobacillns casei显示文摘 | Gosalbes M J Esteban C D Galan J L | 2000 | Appl Environ Microbiol2000，66，11： | 1 |
| 12 | Adrenocorticotropic hormone-secreting pancreatic neuroendocrine carcinoma with multiple organ infections and widespread thrombosis:A case report显示文摘BACKGROUND Ectopic adrenocorticotropic hormone(ACTH)-secreting neuroendocrine tumors are rare diseases.Patients with ACTH-secreting pancreatic neuroendocrine carcinomas have a poor prognosis.Infections and coagulopathies have been reported as the cause of death.However,detailed clinical descriptions of the morbid complications of ACTH-secreting neuroendocrine carcinomas have not been reported.CASE SUMMARY A 78-year-old Japanese woman consulted a medical center due to systemic edema and epigastric discomfort.Laboratory analysis revealed hypercortisolemia with increased ACTH secretion without diurnal variation in serum cortisol level.An enhanced computed tomography(CT)scan revealed a 3-cm tumor in the pancreatic head.The cytological material from endoscopic ultrasound-guided fine-needle aspiration was compatible with ACTHsecreting pancreatic neuroendocrine carcinoma.The Ki-67 index was 40%.She was transferred to Mie University Hospital for surgical treatment.The patient was diagnosed with urinary tract infection,cytomegalovirus hepatitis,esophageal candidiasis,pulmonary infiltrates suspicious for Pneumocystis carinii pneumonia,peripheral deep vein thrombosis,pulmonary embolism,and disseminated intravascular coagulation.The multiple organ infections and thromboses responded well to antimicrobial and anticoagulant therapy.Radioisotope studies disclosed a pancreatic tumor and a metastatic lesion in the liver,whereas somatostatin receptor scintigraphy showed negative findings,suggesting the primary and metastatic tumors were poorly differentiated.A CT scan before admission showed no metastatic liver lesion,suggesting that the pancreatic tumor was rapidly progressing.Instead of surgery,antitumor chemotherapy was indicated.The patient was transferred to another hospital to initiate chemotherapy.However,she died four months later due to the rapidly progressive tumor.CONCLUSION ACTH-secreting pancreatic neuroendocrine neoplasm is a rare disease with a very poor prognosis.The clinical course and acute complications of the tumor remain unreported.Here we report the clinical course of a rapidly progressive case of ACTH-secreting pancreatic neuroendocrine tumor that developed infectious complications due to many types of pathogens in multiple organs,widespread thromboses,pulmonary embolism,and disseminated intravascular coagulation. | Akihiro Yoshihara Kota Nishihama Chisa Inoue Yuko Okano Kazuhito Eguchi Soichiro Tanaka Kanako Maki Valeria Fridman D'Alessandro Atsuro Takeshita Taro Yasuma Mei Uemura Toshinari Suzuki Esteban C Gabazza Yutaka Yano | 2022 | World Journal of Clinical Cases2022，10，17： | 1 |
| 13 | On the Measurement of Polariza- tion 显示文摘 | Esteban J M Ray D C | 1994 | Econometrics1994，62，4： | 1 |
| 14 | Extension of a measure of polarization with an application to the income distribution of five OECD countries显示文摘 | Esteban J Gradfn C Ray D | 2007 | Journal of Economic Inequality2007，5，7： | 1 |
| 15 | On the measurement of polarization 显示文摘 | Esteban JM Ray D C | 1994 | Econometrica1994，，62： | 1 |
| 16 | Laboratory characterisation of shale properties显示文摘 | Josh M Esteban L Plane C D | 2009 | Journal of Petroleum Science and Engineering2009，8889，： | 1 |
| 17 | An Extension of a Measure of Polarization,with an Application to the Income Distribution of Five OECD Countries显示文摘 | Esteban J Cradin C Ray D | | 0，，1： | 1 |
| 18 | Intragrative food-grade expression system based on the lactose regulon of Lactobacillus casei显示文摘 | Gosalbes M J Esteban C D Galan J L | 2000 | Appl Environ Microbiol2000，66，10： | 1 |
| 19 | Integrative food - grade expression system based on the lactose regulon of Lactobacillus casei 显示文摘 | Gosalbes M J Esteban C D Galan J L | 2000 | Applied And Environmetal Microbiolgoy2000，66，： | 1 |
| 20 | Extension of a Measure of Polarization, with an Application to the Income Distril:mtion ofFive DECD Countries显示文摘 | Esteban J Gradin C Ray D | 1999 | Journal of gconmic Inequality1999，，1： | 1 |
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