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1Diabetes mellitus increases risk for colorectal adenomas in younger patients显示文摘AIM:To determine if diabetes mellitus(DM)is associated with increased risk of colorectal adenomas in younger subjects.METHODS:This was a retrospective cohort study of375 patients undergoing index colonoscopy at a single tertiary care center in the United States.Three cohorts of patients matched for exam date and gender were compared:(1)ages 40-49 years with DM;(2)ages40-49 years without DM;and(3)ages 50-59 years without DM.Data collected included demographics,co-morbidities,colonoscopy and pathology results.Adenoma detection rates(ADR)were calculated and compared.Conditional logistic regression analysis was performed to determine the association between each cohort and ADR.RESULTS:One hundred and twenty-five patients ages40-49 with DM met study eligibility criteria.Patients in the other two cohorts were randomly selected,match-ing for date of exam and gender.ADR was 14.4%in those ages 40-49 years without DM,30.4%in those ages 40-49 years with DM,and 32.0%in those ages50-59 years without DM.Compared to those ages40-49 years without DM,ADR was higher in those ages40-49 years with DM(OR=3.1;95%CI:1.5-6.4;P=0.002)and those ages 50-59 years without DM(OR=2.9;95%CI:1.5-5.6;P=0.002).There was no difference between the ADR in those ages 40-49 years with DM and those ages 50-59 years without DM(P=0.83).CONCLUSION:DM was associated with higher risk of colorectal adenomas in patients ages 40-49 years.These subjects harbored as many adenomas as those at the standard screening age of 50-59 years without DM.Hongha T Vu Nneka Ufere Yan Yan Jean S Wang Dayna S Early Jill E Elwing 2014World Journal of Gastroenterology2014,20,22:5
2Intratumoral heterogene- ity of c-erbB-2/neu in invasive mammary carcinomas using fluorescence in- situ hybridization and tissue mieroarray 显示文摘SHIN S J HYJEK E EARLY E 2006Int J Surg Pathol2006,14,4:1
3Normal growth of ultrastruetures in rat left ventricular myocardial cells 显示文摘Page E Early J Power B 1974Cir Res1974,3435,:1
4NIST Reference Densitometer for Visual Diffuse Transmission Density 显示文摘Early E A Cromer C L Xiong X X 1999J lmag Sci and Technol1999,43,2:1
5Morbidity associated with ORIF of intra-articulan calcaneus fractures using a lateral approach显示文摘Harvey E J Grujic L Early J S 2001Foot Ankle Int2001,22,11:1
6Carbon-13 NMR studies of solid urea-formaldehyde resins using cross polarization and magic-angle spinning显示文摘Maciel Gary E Szeverenyi Nikolaus M Early Thomas A 1983Macromolecules1983,16,4:1
7Intercomparison of Visual Diffuse Transmission Density Measurements 显示文摘Buhr E Bergmann D Early E A 2000J Imag Sci and Technol2000,44,2:1
8Intraumoral heterogeneity of her-2/neu in invasive mammary carcinomas using fluorescence insitu hybridization and tissue microarray 显示文摘Shin SJ Hyjek E Early E 2006Int J Surg Pathol2006,14,4:1
9NCCN Clinical Practice Guidelines in Oncology:rectal cancer 显示文摘Engstrom PF Arnoletti JP Benson AB 3rd Chen YJ Choti MA Cooper HS Covey A Dilawari RA Early DS Enzinger PC Fakih MG Fleshman J Jr Fuchs C Greta JL Kiel K Knol JA Leong LA Lin E Mulcahy MF Rao S Ryan DP Saltz L Shibata D Skibber JM Sofocleous C Thomas J Venook AP Willett C 2009J Natl Compr Canc Netw2009,7,:1
10Endo-,Para-,and Ecodormancy:Physiological terminology and classification for dormancy research 显示文摘LANG G A EARLY D E MARTIN G C 1987HortScience1987,22,3:1
11Carbon-13 NMR studies of solid urea-formaldehyde resins using cross polarization and magic-angle spinning显示文摘MACIEL G E SZEVERENYI N M EARLY T A 1983Macromolecules1983,16,4:1
12A prospective study显示文摘Lieto E Orditura M Castellano P Endoscopic intraoperative anastomotic testing may avoid early gastrointestinal anastomotic complications 2011Gastrointest Surg2011,15,1:1
13Creating hybrid team cultures: An empirical test of transnational team functioning 显示文摘Early P C Mosakowski E 2000Academy of Management Journal2000,43,1:1
14An organizational climate intervention associated with increased hand washing and decreased nosocomial infections显示文摘Larson EL Early E Cloonan P 2000Behav Med2000,26,1:1
15Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways 显示文摘Early E Rogers J Davis M 1980Cell1980,20,:1
16Effect of ethrel on growth and yield of corn 显示文摘Early E B Slife F W 1969Agronomy Journal1969,61,:1
17Effects of shade applied at different stages of plant development on corn (Zea mays) production显示文摘Early E B Mcilrath W O Seif R D 1967Crop Science1967,,7:1
18Pore water metal results 显示文摘Klinkhammer G E Early diagenesis in sediments from the eastern equatorial Pacific II 1980Earth and Planetary Science Letters1980,49,1:1
19Intratumoral heterogeneity of her-2/neu in invasive mammary carcinomas using fluorescence in situ hybridization and tissue microarray 显示文摘Shin S J Hyjek E Early E 2006Int J Surg Pathol2006,14,:1
20Intratumoral heterogeneity d her-2/neu in invasive mammary carcinomas usin8 fluorescenceinsitu hybridization and tissue microarray显示文摘Shin SJ Hyjek E Early E 2006Int J Surg Pathol2006,14,4:1
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