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| 1 | Rotational assisted endoscopic retrograde cholangiopancreatography in patients with reconstructive gastrointestinal surgical anatomy显示文摘AIM: To evaluate the success rates of performing therapy utilizing a rotational assisted enteroscopy device in endoscopic retrograde cholangiopancreatography(ERCP) in surgically altered anatomy patients. METHODS: Between June 1, 2009 and November 8, 2012, we performed 42 ERCPs with the use of rotational enteroscopy for patients with altered anatomy(39 with gastric bypass Roux-en-Y, 2 with Billroth Ⅱ gastrectomy, and 1 with hepaticojejunostomy associated with liver transplant). The indications for ERCP were: choledocholithiasis: 13 of 42(30.9%), biliary obstruction suggested on imaging: 20 of 42(47.6%), suspected sphincter of Oddi dysfunction: 4 of 42(9.5%), abnormal liver enzymes: 1 of 42(2.4%), ascending cholangitis: 2 of 42(4.8%), and bile leak: 2 of 42(4.8%). All procedures were completed with the Olympus SIF-Q180 enteroscope and the Endo-Ease Discovery SB overtube produced by Spirus Medical. RESULTS: Successful visualization of the major ampulla was accomplished in 32 of 42 procedures(76.2%). Cannulation of the bile duct was successful in 26 of 32 procedures reaching the major ampulla(81.3%). Successful therapeutic intervention was completed in 24 of 26 procedures in which the bileduct was cannulated(92.3%). The overall intention to treat success rate was 64.3%. In terms of cannulation success, the intention to treat success rate was 61.5%. Ten out of forty two patients(23.8%) required admission to the hospital after procedure for abdominal pain and nausea, and 3 of those 10 patients(7.1%) had a diagnosis of post-ERCP pancreatitis. The average hospital stay was 3 d.CONCLUSION: It is reasonable to consider an attempt at rotational assisted ERCP prior to a surgical intervention to alleviate biliary complications in patients with altered surgical anatomy. | Majed El Zouhairi James B Watson Svetang V Desai David K Swartz Alejandra Castillo-Roth Mahfuzul Haque Paul S Jowell Malcolm S Branch Rebecca A Burbridge | 2015 | World Journal of Gastrointestinal Endoscopy2015,7,3: | 10 |
| 2 | 人血浆硫氧化还原蛋白80随着年龄增长而增加,并在载脂蛋白E基因敲除小鼠中诱导炎症、血管生成和动脉粥样硬化显示文摘硫氧化还原蛋白(thioredoxin,TRX)1是一种普遍存在的12kD的蛋白质,可产生抗氧化和抗炎作用。由巨噬细胞产生的截断形式称为TRX80,其可诱导促炎细胞因子的上调。TRX80还促进小鼠腹膜和人巨噬细胞向促炎M1表型的分化。方法:使用特异性酶联免疫吸附试验测定血浆TRX1和TRX80水平。 | 刘莉 叶鹏 Couchie D Vaisman B Abderrazak A Mahmood DFD Hamza MM Canesi F Diderot V El Hadri K Nègre-Salvayre AE Le Page A Fulop T Remaley AT Rouis M | 2017 | 中华高血压杂志2017,25,6: | 9 |
| 3 | A review of human carcinogens—Part B: biological agents显示文摘 | Véronique Bouvard Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Lamia Benbrahim-Tallaa Neela Guha Crystal Freeman Laurent Galichet Vincent Cogliano | 2009 | Lancet Oncology2009,,4: | 4 |
| 4 | Regulated upon activation,normal T cell expressed and secreted(RANTES)levels in the peripheral blood of patients with Alzheimer’s disease显示文摘Alzheimer’s disease(AD)is the most common type of dementia,but it is very difficult to diagnose with certainty,so many AD studies have attempted to find early and relevant diagnostic markers.Regulated upon activation,normal T cell expressed and secreted(RANTES,also known as C-C chemokine ligand)is a chemokine involved in the migration of T cells and other lymphoid cells.Changes in RANTES levels and its expression in blood or in cerebrospinal fluid have been reported in some neurodegenerative diseases,such as Parkinson’s disease and multiple sclerosis,but also in metabolic diseases in which inflammation plays a role.The aim of this observational study was to assess RANTES levels in peripheral blood as clinical indicators of AD.Plasma levels of RANTES were investigated in 85 AD patients in a relatively early phase of AD(median 8.5 months after diagnosis;39 men and 46 women;average age 75.7 years),and in 78 control subjects(24 men and 54 women;average age 66 years).We found much higher plasma levels of RANTES in AD patients compared to controls.A negative correlation of RANTES levels with age,disease duration,Fazekas scale score,and the medial temporal lobe atrophy(MTA)score(Scheltens’s scale)was found in AD patients,i.e.,the higher levels corresponded to earlier stages of the disease.Plasma RANTES levels were not correlated with cognitive scores.In AD patients,RANTES levels were positively correlated with the levels of pro-inflammatory cytokines interleukin-6 and tumor necrosis factor-α,which is consistent with the wellknown fact that AD is associated with inflammatory processes.RANTES levels were also positively correlated with insulin levels in AD patients,with insulin resistance(HOMA-R)and pancreatic beta cell function(HOMA-F).This study evaluated several clinical and metabolic factors that may affect plasma levels of RANTES,but these factors could not explain the increases in RANTES levels observed in AD patients.Plasma levels of RANTES appear to be an interesting peripheral marker for early stages of AD.The study was approved by the Ethics Committee of Institute of Endocrinology,Prague,Czech Republic on July 22,2011. | Gabriela Vacínová Daniela Vejražkova Robert Rusina Iva Holmerová Hana Vaňková Eva Jarolímová Josef Včelák Běla Bendlová Markéta Vaňková | 2021 | Neural Regeneration Research2021,16,4: | 3 |
| 5 | Effect of sustained virological response on long-term clinical outcome in 113 patients with compensated hepatitis C-related cirrhosis treated by interferon alpha and ribavirin显示文摘AIM:To assess the long-term clinical benefit of sustained virological response(SVR)in patients with hepatitis C virus(HCV)cirrhosis treated by antiviral therapy using mostly ribavirin plus interferon either standard or pegylated.METHODS:One hundred and thirteen patients with uncomplicated HCV biopsy-proven cirrhosis,treated by at least one course of antiviral treatment ≥ 3 mo and followed ≥ 30 mo were included.The occurrence of clinical events hepatocellular carcinoma(HCC),decompensation and death was compared in SVR and non SVR patients.RESULTS:Seventy eight patients received bitherapy and 63 had repeat treatments.SVR was achieved in 37 patients(33%).During a mean follow-up of 7.7 years,clinical events occurred more frequently in non SVR than in SVR patients,with a significant difference for HCC(24/76 vs 1/37,P = 0.01).No SVR patient died while 20/76 non-SVR did(P = 0.002),mainly in relation to HCC(45%).CONCLUSION:In patients with HCV-related cirrhosis,SVR is associated with a significant decrease in the incidence of HCC and mortality during a follow-up period of 7.7 years.This result is a strong argument to perform and repeat antiviral treatments in patients with compensated cirrhosis. | Roland El Braks Nathalie Ganne-Carrié Hélène Fontaine Jacques Paries Véronique Grando-Lemaire Michel Beaugrand Stanislas Pol Jean-Claude Trinchet | 2007 | World Journal of Gastroenterology2007,13,42: | 3 |
| 6 | Coronary physiology assessment in the catheterization laboratory显示文摘Physicians cannot rely solely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischemia. Instead, sound knowledge of coronary vascular physiology and of the methods currently available for its characterization can improve the diagnostic and prognostic accuracy of invasive assessment of the coronary circulation, and help improve clinical decision-making. In this article we summarize the current methods available for a thorough assessment of coronary physiology. | Felipe Díez-delhoyo Enrique Gutiérrez-Ibanes Gerard Loughlin Ricardo Sanz-Ruiz María Eugenia Vázquez-álvarez Fernando Sarnago-Cebada Rocío Angulo-Llanos Ana Casado-Plasencia Jaime Elízaga Francisco Fernández Avilés Diáz | 2015 | World Journal of Cardiology2015,7,9: | 2 |
| 7 | Carcinogenicity of alcoholic beverages显示文摘 | Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Véronique Bouvard Andrea Altieri Vincent Cogliano | 2007 | Lancet Oncology2007,,4: | 2 |
| 8 | Effects of cinnamaldehyde, garlic and juniper berry essential oils on rumen fermentation, blood metabolites, growth performance, and carcass characteristics of growing lambs显示文摘 | Chaves A V Stanford K Dugan M E R eL al | 2008 | Livestock Science2008,117,23: | 1 |
| 9 | Interpretation of Axial Statnamic load Test Using an Automatic Signal Matching Technique 显示文摘 | EL NAGGAR M H BALDINELL M J V | 2000 | Canadian Geotechnical Journal2000,37,5: | 1 |
| 10 | Significance of angiogenesis and microvascular invasion in renal cell carcinoma显示文摘 | Koren R Kugel V el al | 2002 | Pathology Oncology Research2002,8,2: | 1 |
| 11 | Acute effects of righl ventricular apical pacing on left ventricublr synchrony and mechanics 显示文摘 | Delgado V Tops LF Trines SA el al | 2009 | Circ Arrhythmia Electrophysiol2009,2,: | 1 |
| 12 | Effect of near adds on the variability of accommodative response in myopic children 显示文摘 | Sreenivasan V Irving EL Bobier WR | 2011 | Ophthalmie Physiol Opt2011,31,: | 1 |
| 13 | Tracking fish by airborne radar - fishermen could be the winner显示文摘 | GRIFFITHS F B LYNE V D HARRIS G P et el | 1989 | Australian Fisheries1989,48,: | 1 |
| 14 | On minimal order in-verse of discrete - time descriptor systems显示文摘 | El - Tohami M Lovassnagy V Powers D L | 1985 | Int Journal of Con-trol1985,41,4: | 1 |
| 15 | Thoracoscopic local-ization techniques for patients with solitary pulmonary nodule and history of malignancy显示文摘 | SORTINI D FEO C V CARCOFORO P el al | 2005 | Ann Thorac Surg2005,79,: | 1 |
| 16 | The mechanisms of action of phototherapy in the treatment of the most common dermatoses显示文摘 | Bulat V ~itum M Dcdiol I el al | 2011 | Collegium Antropologicum2011,35,2: | 1 |
| 17 | Effects of B and W alloying additions on the formation and stability of lamellar structures in two-phase y-TiAl 显示文摘 | Mazisaz P J Ramanujan R V Liu C T et el | 1997 | Intermetallics1997,5,2: | 1 |
| 18 | Compafison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemia 显示文摘 | Rocha V Comish J Sievers EL | 2001 | Blood2001,97,10: | 1 |
| 19 | The influence of dust stan- dards on the prevalence and severity of coal worker's pneumoconiosis at autopsy in the United States of America 显示文摘 | Val V Douglas P Landsittel EL | 2011 | Arch Pathol Lab Med2011,135,12: | 1 |
| 20 | Large thrombus at the site of primary sutured atrial septal defect associated with pulmonary emboli-sm and treatment by thrombolysis 显示文摘 | Dinekal MH Davutoglu V Soydinc S et el | 2003 | Echocardiography2003,20,6: | 1 |