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| 1 | 青藏高原北部大型走滑断裂带近地表地质变形带特征分析显示文摘阿尔金断裂带、东昆仑断裂带和海原断裂带是青藏高原北部的大型左旋走滑断裂带,具有相对高的地质和GPS滑动速率,地表破裂型地震频发。在阿尔金断裂带阿克塞老城西和半果巴、东昆仑断裂带西大滩和玛沁、海原断裂带松山等地点的探槽地质剖面揭露了这些走滑断裂带累积地质变形带的基本特征。阿尔金断裂带半果巴探槽和阿克塞老城西探槽、东昆仑断裂带西大滩探槽和玛沁探槽揭露出的地质变形带宽度约12m左右;海原断裂带松山拉分盆地边界单条走滑断层地质变形带宽度不足10m,考虑到地震期间拉分盆地可能会出现较严重的变形,则拉分盆地本身也应作为强变形带处理。由此可见,经历过多个地震地表破裂循环的东昆仑断裂带、海原断裂带和阿尔金断裂带其地质变形带的宽度是有限的,具有变形局部化特征。单条走滑断层的地质变形带宽度一般为10余米,比较保守地估计应<30m,走滑断层斜列阶区的地质变形带宽度取决于阶区本身的宽度。 | 徐锡伟 于贵华 陈桂华 李陈侠 张兰凤 Yann Klinger Paul Tapponnier 刘静 | 2007 | 地震地质2007，29，2： | 55 |
| 2 | 昆仑山地震(Mw7.8)破裂行为、变形局部化特征及其构造内涵讨论显示文摘地震地表破裂是地壳弹性应变转化为永久性构造变形的表现形式.2001年昆仑山地震在东昆仑断裂带库赛湖段产生的地表破裂带整体长426km,由西部剪切走滑破裂段、中部张剪切破裂段和东部剪切走滑破裂段等3个相对独立的地表破裂段组成,即昆仑山地震由震级为Mw=6.8,Mw=6.2和Mw≤7.8的3次地震破裂事件组成,其中东段Mw≤7.8级地震为昆仑山地震主震,由4次更次级地震事件组成.野外测量表明,不同段落上单条地表破裂宽度一般介于数米至15m,最大不超过30m;组合地表破裂带的宽度主要取决于几何结构,特别是次级地表破裂带斜列区的宽度,具有变形局部化的基本特征.结合东昆仑断裂带第四纪地质速率与GPS监测应变速率一致性,2001年昆仑山地震地表破裂局部化特征说明,青藏高原北部巴颜喀拉与祁连-柴达木两大块体间的构造变形主要表现为东昆仑断裂带宽度有限的剪切走滑错动,东昆仑山断裂带南北两侧块体具有整体运动特征.地震破裂局部化特征对确定重大工程、居民住宅和生命线工程等免遭走滑断层同震地表错动引起直接破坏的避让带宽度具有十分重要现实意义. | 徐锡伟 于贵华 马文涛 林传勇 Yann Klinger Paul Tapponnier | 2008 | 中国科学(D辑)2008，38，7： | 42 |
| 3 | 2013年芦山地震序列震源机制与震源区构造变形特征分析显示文摘基于四川区域地震台网记录的波形资料,利用CAP波形反演方法,同时获取了2013年4月20日芦山M7.0级地震序列中88个M≥3.0级地震的震源机制解、震源矩心深度与矩震级,进而利用应变花(strain rosette)和面应变(areal strain)As值,分析了芦山地震序列震源机制和震源区构造运动与变形特征.获得的主要结果有:(1)芦山M7.0级主震破裂面参数为走向219°/倾角43°/滑动角101°,矩震级为MW6.55,震源矩心深度15km.芦山地震余震区沿龙门山断裂带走向长约37km、垂直断裂带走向宽约16km.主震两侧余震呈不对称分布,主震南西侧余震区长约27km、北东侧长约10km.余震分布在7~22km深度区间,优势分布深度为9~14km,序列平均深度约13km,多数余震分布在主震上部.粗略估计的芦山地震震源体体积为37km×16km×16km.(2)面应变As值统计显示,芦山地震序列以逆冲型地震占绝对优势,所占比例超过93%.序列主要受倾向NW、倾角约45°的近NESW向逆冲断层控制;部分余震发生在与上述主发震断层近乎垂直的倾向SE的反冲断层上;龙门山断裂带前山断裂可能参与了部分余震活动.P轴近水平且优势方位单一,呈NW-SE向,与龙门山断裂带南段所处区域构造应力场方向一致,反映芦山地震震源区主要受区域构造应力场控制,芦山地震是近NE-SW向断层在近水平的NW-SE向主压应力挤压作用下发生逆冲运动的结果.序列中6次非逆冲型地震均发生在主震震中附近,且主震震中附近P轴仰角变化明显,表明主震对其震中附近局部区域存在明显的应力扰动.(3)序列整体及不同震级段的应变花均呈NW向挤压白瓣形态,显示芦山地震震源区深部构造呈逆冲运动、NW向纯挤压变形.各震级段的应变花方位与形状一致,具有震级自相似性特征,揭示震源区深部构造运动和变形模式与震级无关.(4)不同深度的应变花形态以NW-NWW向挤压白瓣为优势,显示震源区构造无论是总体还是分段均以NW-NWW向挤压变形为特征.但应变花方位与形状随深度仍具有较明显的变化,可能反映了震源区构造变形在深度方向上存在分段差异.(5)芦山地震震源体尺度较小,且主震未发生在龙门山断裂带南段主干断裂上,南段长期积累的应变能未能得到充分释放,南段仍存在发生强震的危险. | 易桂喜 龙锋 Amaury Vallage Yann Klinger 梁明剑 王思维 | 2016 | 地球物理学报2016，59，10： | 46 |
| 4 | Changes in reproductive investment with altitude in an alpine plant显示文摘Aims In perennial species,the allocation of resources to reproduction results in a reduction of allocation to vegetative growth and,therefore,impacts future reproductive success.As a consequence,variation in this trade-off is among the most important driving forces in the life-history evolution of perennial plants and can lead to locally adapted genotypes.In addition to genetic variation,phenotypic plasticity might also contribute to local adaptation of plants to local conditions by mediating changes in reproductive allocation.Knowledge on the importance of genetic and environmental effects on the tradeoff between reproduction and vegetative growth is therefore essential to understand how plants may respond to environmental changes.Methods We conducted a transplant experiment along an altitudinal gradient from 425to1921 min the frontrange of the Western Alps of Switzerland to assess the influence of both altitudinal origin of populations and altitude of growing site on growth,reproductive investment and local adaptation in Poa alpina.Important findings In our study,the investment in reproduction increased with plant size.Plant growth and the relative importance of reproductive investment decreased in populations originating from higher altitudes compared to populations originating from lower altitudes.The changes in reproductive investment were mainly explained by differences in plant size.In contrast to genetic effects,phenotypic plasticity of all traits measured was low and not related to altitude.As a result,the population from the lowest altitude of origin performed best at all sites.Our results indicate that in P.alpina genetic differences in growth and reproductive investment are related to local conditions affecting growth,i.e.interspecific competition and soil moisture content. | Yann Hautier Christophe F.Randin Jurg Stocklin Antoine Guisan | 2009 | Journal of Plant Ecology2009，2，3： | 17 |
| 5 | Rupture behavior and deformation localization of the Kunlunshan earthquake (M_w7.8) and their tectonic implications显示文摘Earthquake surface rupture is the result of transformation from crustal elastic strain accumulation to permanent tectonic deformation. The surface rupture zone produced by the 2001 Kunlunshan earth- quake (Mw7.8) on the Kusaihu segment of the Kunlun fault extends over 426 km. It consists of three relatively independent surface rupture sections: the western strike-slip section, the middle transten- sional section and the eastern strike-slip section. Hence this implies that the Kunlunshan earthquake is composed of three earthquake rupturing events, i.e. the Mw=6.8, Mw=6.2 and Mw≤7.8 events, respec- tively. The Mw≤7.8 earthquake, along the eastern section, is the main shock of the Kunlunshan earth- quake, further decomposed into four rupturing subevents. Field measurements indicate that the width of a single surface break on different sections ranges from several meters to 15 m, with a maximum value of less than 30 m. The width of the surface rupture zone that consists of en echelon breaks de- pends on its geometric structures, especially the stepover width of the secondary surface rupture zones in en echelon, displaying a basic feature of deformation localization. Consistency between the Quaternary geologic slip rate, the GPS-monitored strain rate and the localization of the surface rup- tures of the 2001 Kunlunshan earthquake may indicate that the tectonic deformation between the Ba- yan Har block and Qilian-Qaidam block in the northern Tibetan Plateau is characterized by strike-slip faulting along the limited width of the Kunlun fault, while the blocks themselves on both sides of the Kunlun fault are characterized by block motion. The localization of earthquake surface rupture zone is of great significance to determine the width of the fault-surface-rupture hazard zone, along which direct destruction will be caused by co-seismic surface rupturing along a strike-slip fault, that should be considered before the major engineering project, residental buildings and life line construction. | KLINGER Yann TAPPONNIER Paul | 2008 | Science China Earth Sciences2008，51，10： | 15 |
| 6 | 富蕴断裂:低应变速率条件下断层滑动习性显示文摘富蕴断裂是阿尔泰地区低应变速率条件下的典型右旋走滑断层之一。野外考察和3个观测点的3D陆地LiDAR扫描DEM影像断错地貌恢复、重建,结合高分辨率卫星影像解译等进一步证实,1931年富蕴地震同震右旋走滑位移平均值为(6.3±1.2)m,且沿富蕴断裂向南北两端缓慢、平稳衰减,中部同震位移最大值为(6.7±0.5)m,而不是前人给出的10~14m;包含2~5次地震的同震累积位移值为1931年富蕴地震相同地点同震位移的整数倍,表明富蕴断裂大地震复发服从特征地震模型。2个观测点多级地貌面宇宙成因核素(10Be)系统测年数据,进一步限定富蕴断裂晚更新世以来的右旋走滑速率为(0.76±0.24)mm/a,大地震复发间隔(9700±3300)a。低滑动速率和长周期特征地震复发模型可能为板块间相互作用产生的远程应变效应的基本特征。 | 徐锡伟 孙鑫喆 谭锡斌 李康 于贵华 Marie Etchebes Yann Klinger Paul Tapponnier J.Van Der Woerd | 2012 | 地震地质2012，34，4： | 10 |
| 7 | 锂离子电池加速老化温度应力的滥用边界显示文摘为了探寻加速老化合适的温度应力区间,设计了温度变化为30~80℃的循环老化实验,通过电池外特性分析与解体分析等手段对锂离子电池老化机理进行了探讨。结果表明:老化速率随着温度的升高先降低、再升高。基于老化速率,将温度工况分为常温(30~56℃)、中高温(56~68℃)、高温(68~80℃)3个区域。在常温区域,老化速率随着温度升高而降低,锂离子电池存在析锂现象;在高温区域,电池电极出现活性物质脱落现象,导致锂离子电池容量的衰减;而在中高温区域,通过活化能计算判断电池老化机理为固体电解质界面膜(SEI)的生长。该研究成果可以指导加速老化实验的设计,也为寿命预测模型的开发提供参考。 | 吴正国 张剑波 李哲 LIAW Bor Yann | 2018 | 汽车安全与节能学报2018，9，1： | 10 |
| 8 | 颗粒增强金属基复合材料的结构建模与力学模拟研究进展显示文摘颗粒增强金属基复合材料具有高模量、高强度及高耐磨等优异性能,其材料体系庞杂、复合结构繁复,力学性能指标众多。通过结构建模与力学模拟的系统研究,能够有效揭示复合材料的构效关系与组织演变规律,进而指导其设计、制备、加工与应用全流程研究。开展多尺度建模计算,并与宏、微观实验相融合,以及利用以数据库技术、高通量计算与大数据挖掘为主要特征的材料信息学研究,可实现金属基复合材料的“组分-工艺-结构-性能”内禀关系的科学内涵描述。首先回顾了颗粒增强金属基复合材料建模计算的主要研究方法,然后对其结构建模研究现状进行了介绍,进而围绕界面特性与力学模拟进行了综合述评,最后对建模拟实结合材料基因工程技术的未来发展进行了展望。 | 俞洋 苏益士 BERTHELOT Yann 欧阳求保 郭强 张荻 | 2020 | 中国材料进展2020，39，3： | 8 |
| 9 | 汶川M_w 7.9级地震同震断层陡坎类型与级联破裂模型显示文摘2008年5月12日,汶川Mw7.9级地震在青藏高原东缘沿龙门山逆冲断裂带中段形成了两条NE向和一条NW向逆冲走滑型地表破裂。依据同震地表陡坎形态特征,将其分为8种类型:逆断层陡坎、上盘垮塌陡坎、挤压推覆陡坎、右旋挤压推覆陡坎、断层相关褶皱陡坎、后冲挤压陡坎、上冲叠覆陡坎和局部正断层陡坎。汶川地震所形成的同震地表破裂主要由以逆冲为主的映秀破裂段和兼具逆冲、右旋走滑的北川破裂段两部分组成,这两个破裂段分别对应于Mw7.8与Mw7.6级地震事件;它们还可进一步细分为分别对应于Mw7.5、Mw7.7、Mw7.0和Mw7.5等4个次级事件的4个次级破裂段。这些次级破裂段的级联破裂可以用来解释为什么汶川地震的持续时间长达110 s。余震震源机制分析结果表明,发震断层的倾角随深度的增加而变缓,且从西南向北东逐渐变陡可以用来解释走滑分量增加的成因。此次大地震还表明,沿青藏高原东缘地形抬高的主要驱动力可能是地壳挤压缩短,而不一定是下地壳物质流动和膨胀引起上地壳的隆升。 | 于贵华 徐锡伟 Yann Klinger 刁桂苓 陈桂华 冯向东 李陈侠 朱艾斓 袁仁茂 郭婷婷 谭锡斌 安艳芬 孙鑫喆 | 2010 | 地学前缘2010，17，5： | 8 |
| 10 | Retinal vessel oxygen saturation in healthy subjects and early branch retinal vein occlusion显示文摘AIM: To measure the retinal oxygen saturation in healthy subjects and early branch retinal vein occlusion(BRVO) in Chinese population.METHODS: The retinal vessel oxygen saturation of the healthy subjects and BRVO patients were measured by a noninvasive retinal oximeter(Oxymap ehf.,Reykjavik,Iceland).RESULTS: The study included 22 patients with unilateral BRVO(mean age: 55.1±8.8y) in the study group and 91 healthy participants(mean age: 37.5±14.0y) in the control group.In the healthy individuals,mean arterial and venous oxygen saturation were significantly(P<0.001)higher in the superior nasal quadrant(98.5%±10.1%and 57.3%±8.7%,respectively) than in the inferior nasal quadrant(94.2%±9.0% and 54.1%±9.6%,respectively),followed by the superior temporal quadrant(89.1%±10.1%and 51.9%±8.9%,respectively) and the inferior temporal quadrant(86.4%±9.4% and 46.6%±9.6%,respectively).In patients with ischemic BRVO,arterial oxymetric values were significantly higher and venous measurements significantly lower for the affected vessel(107.5%±9.7% and46.4%±14.2%,respectively) than the unaffected vessel in the same eye(99.2%±12.2% and 55.5%±7.9%,respectively)and as compared to the vessel in the unaffected fellow eye(93.1%±6.9% and 55.7%±6.8%)(P=0.005 and P=0.02,respectively).In the patients with non-ischemic BRVO,mean venous oxygen saturation was lower in the affected vein(39.8%±12.2%) than in the unaffected vessels of the same eye(50.8%±10.5%) and in the fellow eye(58.21%±5.7%)(P=0.03).Mean arterial oxygen saturation did not differ significantly(P=0.42) between all three groups.CONCLUSION: In patients with BRVO,the venous oxygen saturation in the affected vessels is decreased potentially due to decreased blood velocity and flow.Interestingly,thearterial oxygen saturation in eyes with ischemic BRVO is increased in the affected arteries. | Jing-Yan Yang Bing You Qian Wang Szy Yann Chan Jost B.Jonas Wen-Bin Wei | 2017 | International Journal of Ophthalmology(English edition)2017，10，2： | 8 |
| 11 | 以飞人的眼晴看世界——独特的贝特朗高空摄影显示文摘春季,卢森堡博物馆举办了一个大型的高空摄影展览,摄影家在博物馆的门口悬挂了110幅巨幅照片,让所有过路的行人都能免费欣赏照片。“我的照片不是为了展览,而是对地球的反映。”摄影家的这个鲜明的主题吸引了众多的参观者,两周内的参观人数高达7万, | 赵凌 Yann Arthus Bertrand | 2007 | 大美术2007，，2： | 7 |
| 12 | 阿尔金断裂带阿克塞段半果巴探槽揭露的古地震事件显示文摘阿尔金断裂带是青藏高原北边界的1条近EW向延伸长约1600km的大型左旋走滑断裂带,也是晚第四纪活动性最强的断裂带之一,被分为11个破裂段。利用高精度卫星影像结合野外地质地貌调查,通过Trimble VX扫描测量了阿尔金断裂带阿克塞段半果巴观察点的断错微地貌,显示冲沟左岸T1阶地保存了最新1次地震的位错约6~7m。选择冲沟右岸跨断塞塘开挖探槽,采集了14C样品进行年代测定,对该探槽的古地震事件进行了分析。探槽揭示了12套地层单元,记录了4次古地震事件,结合之前的研究,利用逐次限定方法可以把阿克塞段的最新2次古地震事件的发生时间分别限定在1 180a BP左右和507~230a BP。 | 李康 徐锡伟 罗浩 Paul Tapponnier Yann Klinger 高明星 | 2016 | 地震地质2016，38，3： | 6 |
| 13 | 含水喷射器装置性能的实验研究显示文摘当喷射器应用于天然气开采和海水淡化领域时,由于工作流体或引射流体常携带少量水,喷射器常处于气液两相运行状态。本文对含水喷射器装置性能进行了实验研究,获得了不同工作压力和背压下,喷射器性能的变化规律。研究发现,当喷射器临界运行时,加水对喷射器性能影响很小,引射比变化在2.7%之内;而喷射器非临界运行时,气液两相运行时引射比性能变差,与单相运行时相比,引射比最大减小了17%。 | 陈伟雄 种道彤 严俊杰 王进仕 Yann Bartosiewicz | 2014 | 工程热物理学报2014，35，4： | 5 |
| 14 | 甲基丙烯酸甲酯聚合动力学和分子量模型及仿真显示文摘考虑甲基丙烯酸甲酯聚合过程中体积收缩 ,反应物和生成物的浓度变化 ,以及由于凝胶、玻璃化和笼闭等效应对各速率常数和物性参数的影响 ,从基元反应和物料平衡出发 ,推导了半间歇、有链转移剂参与情况下的聚合动力学和分子量模型 .用模型仿真计算了聚合温度、引发剂、溶剂和链转移剂的种类和浓度等对甲基丙烯酸甲酯聚合动力学和聚合过程中分子量变化的影响规律 ,并与实验和文献数据进行比较 . | 单国荣 Gilles Fevotte Yann LE Gorrec | 2002 | 高等学校化学学报2002，23，11： | 5 |
| 15 | Seismotectonics of the 2008 and 2009 Qaidam Earthquakes and its Implication for Regional Tectonics显示文摘Three magnitude >6 earthquakes struck Qaidam, Qinghai province, China, in November 10th 2008, August 28th and 31st 2009 respectively. The Zongwulongshan fault has often been designated as the active seismogenic structure, although it is at odd with the data. Our continuous GPS station (CGPS), the Xiao Qaidam station, located in the north of the Qaidam basin, is less than 30 km to the southwest of the 2008 earthquake. This CGPS station recorded the near field co-seismic deformation. Here we analyzed the co-seismic dislocation based on the GPS time series and the rupture processes from focal mechanism for the three earthquakes. The aftershocks were relocated to constrain the spatial characteristics of the 2008 and 2009 Qaidam earthquakes. Field geological and geomorphological investigation and interpretation of satellite images show that the Xitieshan fault and Zongwulongshan fault were activated as left lateral thrust during the late Quaternary. Evidence of folding can also be identified. Integrated analyses based on our data and the regional tectonic environment show that the Xitieshan fault is the fault responsible for the 2008 Qaidam earthquake, which is a low dip angle thrust with left lateral strike slip. The Zongwulongshan fault is the seismogenic fault of the 2009 earthquakes, which is a south dipping back thrust of the northern marginal thrust system of the Qaidam basin. Folding takes a significant part of the deformation in the northern marginal thrust system of the Qaidam basin, dominating the contemporary structure style of the northern margin of the Qaidam basin and Qilianshan tectonic system. In this region, this fault and fold system dominates the earthquake activities with frequent small magnitude earthquakes. | CHEN Guihua XU Xiwei ZHU Ailan ZHANG Xiaoqing YUAN Renmao Yann KLINGER Jean-Mathieu NOCQUET | 2013 | Acta Geologica Sinica(English Edition)2013，87，2： | 5 |
| 16 | Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle显示文摘鼠科的骨胳的肌肉包含造血的干细胞,而是这个潜力到目前为止没被学习份量上或品质上试管内。确定造血的干细胞潜力,我们在 long-termculture 开始使用了高度净化的 SP/CD45 (+) 房间房间(LTC-IC ) 试金。从鼠科的肌肉净化的 SP/CD45 (+) 房间人口被发现从肌肉与 1/640 .Single-cell-sorted SP/CD45 (+) 房间的 LTC-IC 频率举办重要干细胞活动在白天 16 点的展出柔韧的 proliferative 活动试管内(380 褶层扩大) ,特别在有 OP-9 层的文化以后,那也支持胚胎的干细胞。放大房间人口与 myeloid 的证据从单个房间 exhibitedmultilineage 区别能力发源,淋巴并且 NK 房间标记。因此,我们的结果证明能被 LTC-IC 试金确定的造血的干细胞第一次也在鼠科的骨胳的肌肉和表演存在,在单个房间的水平,这些房间展出多行的年龄区别能力和主要 proliferative 潜力。 | Celine Haond Frangoise Farace Martine Guillier Yann Lecluse Frederic Mazurier William Vainchenker Ali G Turhan | 2007 | Cell Research2007，17，9： | 4 |
| 17 | A review of human carcinogens—Part B: biological agents显示文摘 | Véronique Bouvard Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Lamia Benbrahim-Tallaa Neela Guha Crystal Freeman Laurent Galichet Vincent Cogliano | 2009 | Lancet Oncology2009，，4： | 4 |
| 18 | 钨极稀有气体电弧辐射及其在能量平衡中的作用显示文摘为研究钨极稀有气体(TIG)电弧的辐射属性,计算了氩等离子体在5000~25000K温度范围内的净辐射系数,建立了一种二维、稳态的电弧-钨极-水冷铜模型,获得了电弧辐射强度分布、电弧全谱及非真空紫外光谱的辐射功率。引入了辐射强度与欧姆热和辐射强度之和的比值系数,通过分析该系数在电弧中的分布状况,发现辐射在电弧主体区域对热量的散失起决定作用,而传输热在能量平衡中的作用随电弧位置变化。 | 王飞 李桓 杨珂 Cressault Yann Teulet Philippe | 2018 | 光学学报2018，38，7： | 3 |
| 19 | Resource economics and coordination among above- and below-ground functional traits of three dominant shrubs from the Chilean coastal desert显示文摘Aims Plant functional traits determine how plants respond to environmen-tal factors and influence ecosystem processes.Among them,root traits and analyses of relations between above and below-ground traits in natural communities are scarce.Methods we characterized a set of above-and below-ground traits of three dominant shrub species in a semiarid shrub-steppe that had contrasting leaf pheno-logical habits(deciduous,semideciduous and evergreen).We ana-lysed if there was coordination among above-and below-ground resource economics patterns:i.e.patterns of biomass allocation,construction costs and lifespan.Important Findings Above-and below-ground traits and their resource economics relations pointed to species-specific functional strategies to cope with drought and poor soils and to a species ranking of fast to slow whole-plant strategies in terms of resource uptake,biomass con-struction costs and turnover.The deciduous shrub,Proustia cunei-folia,had relatively deep and even distribution of roots,and high proportion of short-lived tissues of low C construction costs:it had high fine to coarse root and high leaf-to-stem biomass ratios,high specific leaf area(SLA),and stems of low wood density.This strat-egy allows Proustia to maximize and coordinate above-and below-ground resources uptake as long as the most limiting factor(water)is available,but at the cost of having relative high plant biomass turnover.The evergreen Porlieria chilensis,instead,displayed a more conservative and slow strategy in terms of resource econom-ics.It had~80%of the roots in the 40 cm topsoil profile,low pro-portion of fine compared with coarse roots and low leaf-to-stem ratios,low SLA and stems of high wood density,i.e.it invested in C costly tissues that,overall,persist longer but probably at the cost of having lower plant resource uptake rates.Traits in the semide-ciduous Adesmia bedwellii were in between these two functional extremes.Our results revealed high functional diversity and above-and below-ground complementarity in resource economics among these three codominant species in the Chilean coastal desert. | Joaquín Morales Francisco A.Squeo Yann Tracol Cristina Armas Julio R.Gutiérrez | 2015 | Journal of Plant Ecology2015，8，1： | 3 |
| 20 | Idarubicin vs doxorubicin in transarterial chemoembolization of intermediate stage hepatocellular carcinoma显示文摘BACKGROUND Liver cancer is the fifth most common cancer and the second cause of cancerrelated deaths worldwide.Transarterial chemoembolization(TACE)is the best treatment of intermediate hepatocellular carcinoma(HCC).Doxorubicin is the most commonly used drug despite a low level of evidence.AIM To compare the objective response rate of idarubicin-based TACE(Ida-TACE)against doxorubicin-based TACE(Dox-TACE)in intermediate stage HCC.METHODS Between January 2012 and December 2014,all patients treated with TACE at our academic hospital were screened.Inclusion criteria were patients with Child-Pugh score A or B,a performance status below or equal to 1,and no prior TACE.Either lipiodol TACE or drug-eluting beads TACE could be performed with 10 mg of idarubicin or 50 mg of doxorubicin.Each patient treated with idarubicin was matched with two doxorubicin-treated patients.The TACE response was assessed by independent radiologists according to the mRECIST criteria.RESULTS Sixty patients were treated with doxorubicin and thirty with idarubicin.There were 93%and 87%of cirrhotic patients and 87%and 70%of Child-Pugh A in the doxorubicin and idarubicin groups,respectively.The median number of HCC per patient was two in both groups with 31%and 26%of single nodules in doxorubicin and idarubicin groups,respectively.Objective response rate after first TACE was 76.7%and 73.3%(P=0.797)with 41.7%and 40.0%complete response in doxorubicin and idarubicin groups,respectively.Progression-free survival was 7.7 mo in both groups,and liver transplant-free survival was 24.9 mo and 21.9 mo in doxorubicin and idarubicin groups,respectively.Safety profiles were similar in both groups,with grade 3-4 adverse events in 35%of Dox-TACE and 43%of Ida-TACEs.CONCLUSION Ida-TACE and Dox-TACE showed comparable results in terms of efficacy and safety.Ida-TACE may represent an interesting alternative to Dox-TACE in the management of patients with intermediate stage HCC. | Gael Stephane Roth Yann Teyssier Melodie Abousalihac Arnaud Seigneurin Julien Ghelfi Christian Sengel Thomas Decaens | 2020 | World Journal of Gastroenterology2020，26，3： | 3 |
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