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| 1 | Endoscopic pancreatic sphincterotomy:indications,outcome,and a safe stentless technique显示文摘Endoscopicpancreaticsphincterotomy:indications,outcome,andasafestentlesstechniquericElton,MD,DouglasA.Howel,MD,WilisG.Parsons... | Eric Elton, MD, Douglas A. Howell, MD, Willis G. Parsons, MD, Tahir Qaseem, MD, Brian L. Hanson, MDPortland, MaineDivision of Gastroenterology, Maine Medical Center, Portland, Maine | 1998 | World Journal of Gastroenterology1998，4，3： | 16 |
| 2 | Impact of osteoporosis in dental implants:A systematic review显示文摘AIM: To assess the failure and bone-to-implant contact rate of dental implants placed on osteoporotic subjects. METHODS: Extensive examination strategies were created to classify studies for this systematic review. MEDLINE(via Pub Med) and EMBASE database were examined for studies in English up to and including May 2014. The examination presented a combination of the MeS H words described as follow: 'osteoporosis' or 'osteopenia' or 'estrogen deficiency' AND 'implant' or 'dental implant' or 'osseointegration'. Assessment of clinical and/or histological peri-implant conditions in osteoporosis subjects treated with titanium dental implants. The examination included a combination of the MeS H terms described as follow: 'osteoporosis' or 'osteopenia' or 'estrogen deficiency' AND 'implant' or 'dental implant' or 'osseointegration'.RESULTS: Of 943 potentially eligible articles, 12 were included in the study. A total of 133 subjects with osteoporosis, 73 subjects diagnosed with osteopenia and 708 healthy subjects were assessed in this systematic review. In these subjects were installed 367, 205, 2981 dental implants in osteoporotic, osteopenic and healthy subjects, respectively. The failure rate of dental implant was 10.9% in osteoporotic subjects, 8.29% in osteopenic and 11.43% in healthy ones. Bone-to-implant contact obtained from retrieved implants ranged between 49.96% to 47.84%, for osteoporosis and non-osteoporotic subjects. CONCLUSION: Osteoporotic subjects presented higher rates of implant loss, however, there is a lower evidence to strengthen or refute the hypothesis that osteoporosis may have detrimental effects on bone healing. Consequently, final conclusions regarding the effect of osteoporosis in dental implant therapy cannot be made at this time. There are no randomized clinical trial accessible for evaluation and the retrospectivenature of the evaluated studies shall be taken in account when interpreting this study. | Gabriela Giro Leandro Chambrone Abrao Goldstein Jose Augusto Rodrigues Elton Zenóbio Magda Feres Luciene Cristina Figueiredo Alessandra Cassoni Jamil Awad Shibli | 2015 | World Journal of Orthopedics2015，6，2： | 11 |
| 3 | Non-invasive tests for the prediction of primary hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is one of the most common malignancies in the world and it is one of the main complications of cirrhosis and portal hypertension.Even in the presence of a well-established follow-up protocol for cirrhotic patients,to date poor data are available on predictive markers for primary HCC occurrence in the setting of compensated advanced chronic liver disease patients(cACLD).The gold standard method to evaluate the prognosis of patients with cACLD,beyond liver fibrosis assessed with histology,is the measurement of the hepatic venous pressure gradient(HVPG).An HVPG≥10 mmHg has been related to an increased risk of HCC in cACLD patients.However,these methods are burdened by additional costs and risks for patients and are mostly available only in referral centers.In the last decade increasing research has focused on the evaluation of several,simple,non-invasive tests(NITs)as predictors of HCC development.We reviewed the currently available literature on biochemical and ultrasound-based scores developed for the noninvasive evaluation of liver fibrosis and portal hypertension in predicting primary HCC.We found that the most reliable methods to assess HCC risk were the liver stiffness measurement,the aspartate aminotransferase to platelet ratio index score and the fibrosis-4 index.Other promising NITs need further investigations and validation for different liver disease aetiologies. | Giovanni Marasco Antonio Colecchia Giovanni Silva Benedetta Rossini Leonardo Henry Eusebi Federico Ravaioli Elton Dajti Luigina Vanessa Alemanni Luigi Colecchia Matteo Renzulli Rita Golfieri Davide Festi | 2020 | World Journal of Gastroenterology2020，26，24： | 8 |
| 4 | Spleen stiffness mirrors changes in portal hypertension after successful interferon-free therapy in chronic-hepatitis C virus patients显示文摘AIM To investigate changes in spleen stiffness measurements(SSMs) and other non-invasive tests(NITs) after treatment with direct-acting antivirals(DAAs) and identify predictors of SSM change after sustainedvirological response(SVR). METHODS We retrospectively analysed 146 advanced-chronic liver disease(ACLD) patients treated with DAA with available paired SSM at baseline and SVR24. Liver stiffness(LSM), spleen diameter(SD), platelet count(PLT) and liver stiffness-spleen diameter to platelet ratio score(LSPS) were also investigated. LSM ≥ 21 k Pa was used as a cut-off to rule-in clinically significant portal hypertension(CSPH). SSM reduction > 20% from baseline was defined as significant.RESULTS SSM significantly decreased at SVR24, in both patients with and without CSPH; in 44.8% of cases, SSM reduction was > 20%. LSPS significantly improved in the entire cohort at SVR24; SD and PLT changed significantly only in patients without CSPH. LSM significantly decreased in 65.7% of patients and also in 2/3 patients in whom SSM did not decrease. The independent predictor of decreased SSM was median relative change of LSM. CSPH persisted in 54.4% patients after SVR. Delta LSM and baseline SSM were independent factors associated with CSPH persistence.CONCLUSION SSM and other NITs significantly decrease after SVR, although differently according to the patient's clinical condition. SSM faithfully reflects changes in portal hypertension and could represent a useful NIT for the follow-up of these patients. | Federico Ravaioli Antonio Colecchia Elton Dajti Giovanni Marasco Luigina Vanessa Alemanni Mariarosa Tamè Francesco Azzaroli Stefano Brillanti Giuseppe Mazzella Davide Festi | 2018 | World Journal of Hepatology2018，10，10： | 3 |
| 5 | Antibiotic prophylaxis in patients with cirrhosis: Current evidence for clinical practice显示文摘Patients with cirrhosis show an increased susceptibility to infection due to disease-related immune-dysfunction.Bacterial infection therefore represents a common,often detrimental event in patients with advanced liver disease,since it can worsen portal hypertension and impair the function of hepatic and extrahepatic organs.Among pharmacological strategies to prevent infection,antibiotic prophylaxis remains the first-choice,especially in high-risk groups,such as patients with acute variceal bleeding,low ascitic fluid proteins,and prior episodes of spontaneous bacterial peritonitis.Nevertheless,antibiotic prophylaxis has to deal with the changing bacterial epidemiology in cirrhosis,with increased rates of gram-positive bacteria and multidrug resistant rods,warnings about quinolonesrelated side effects,and low prescription adherence.Short-term antibiotic prophylaxis is applied in many other settings during hospitalization,such as before interventional or surgical procedures,but often without knowledge of local bacterial epidemiology and without strict adherence to antimicrobial stewardship.This paper offers a detailed overview on the application of antibiotic prophylaxis in cirrhosis,according to the current evidence. | Alberto Ferrarese Nicola Passigato Caterina Cusumano Stefano Gemini Angelo Tonon Elton Dajti Giovanni Marasco Federico Ravaioli Antonio Colecchia | 2021 | World Journal of Hepatology2021，13，8： | 2 |
| 6 | Platelet Size in Stroke Patients显示文摘 | T. MRCP(UK) O’Malley P. Langhorne R.A. Elton C. Stewart | 1995 | Stroke A Journal of Cerebral Circulation1995，，6： | 2 |
| 7 | The potential to deposit good quality thin films atrelatively mater显示文摘 | BECKER R S ZHENG Tan ELTON J | 1986 | Sol Energy Mater1986，13，： | 1 |
| 8 | Molecular cloning of the human angiotensin Ⅱ type 2 receptor cDNA显示文摘 | Martin MM Su B Elton TS | 1994 | Biochem Biophys Res Commun1994，205，1： | 1 |
| 9 | Multiple logistic regression analysis of plasma paraquat concentrations as a predictor of outcome in 375 cases of paraquat poisoning 显示文摘 | Jones AL Elton R Flanagan R | 1999 | Q J Med1999，92，10： | 1 |
| 10 | Insulin Resistance in Adult Rat Offspring Associated with Maternal Dietary Fat and Alcohol Consumption 显示文摘 | Elton CW Pennington JS Lynch SA | 2002 | J Endocrinol2002，173，1： | 1 |
| 11 | Marginal Stockholder Tax Hates and the Clientele Effect 显示文摘 | Elton E J Gruber M 1 | 1970 | The Review of Economics and Statistics1970，52，1： | 1 |
| 12 | Multiple logistic regression analysis of plasma paraquat concentrations as predictor of outcome in 375 cases of paraquat poisoning显示文摘 | Jones Air Elton R Flanagan R | 1999 | QJM1999，92，10： | 1 |
| 13 | Interaction of the influenza virus nucleoprotein with the cellular CRMl-mediated nuclear export pathway显示文摘 | ELTON D SIMPSON-HOLLEY M ARCHER K | 2001 | J Virol2001，75，1： | 1 |
| 14 | Ps2 is an independent factor ofgood prognosis in primary breast cancer显示文摘 | Thompson AM Hawkins 1Lk Elton BA | 1993 | Br J Cancer1993，68，1： | 1 |
| 15 | Equine influenza-surveillance and control 显示文摘 | Cullinane A Elton D Mumford J | 2010 | Influenza Other Respi Viruses2010，4，6： | 1 |
| 16 | Reduction of the thermoplastic melt haz-ard of polyester fabric through the application of a radi-ation cross-linking technique显示文摘 | Stuart Elton | 1998 | Fire and Materials1998，22，1： | 1 |
| 17 | Heartrate control with adrenergic blockade:clinical outcomes in car-diovascular medicine显示文摘 | FELDMAN D ELTON TS MENACHEMI DM | 2010 | Vasc Health Risk Manag2010，6，： | 1 |
| 18 | Multiple logistic regression analysis of plasma paraquat concentrations as a predictor of outcome in 375 cases of paraquat poisoning显示文摘 | Jones L Elton R Flanagan R | | 0，，： | 1 |
| 19 | Aromatase activity in adipose tissue from breast quadrants:a link with tumour site显示文摘 | O'Neill JS Elton RA Miller WR | | 0，，： | 1 |
| 20 | The Persistence of Risk Adjusted Mutual Fund Performance显示文摘 | Gruber M Blake M | 1996 | Journal of Business1996，69，2： | 1 |
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