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211篇 您的检索式:作者名="Elzen"
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1WONCA研究论文摘要汇编--老年亚临床甲状腺功能减退治疗策略的国际变化趋势:一项基于案例的调查显示文摘背景关于亚临床甲状腺功能减退治疗效果的证据十分有限,特别是对于老年患者的治疗效果。目的探讨全科医生在不同国家和针对不同类型的患者对老年亚临床甲状腺功能减退治疗的不同方式。设计和环境在荷兰、德国、英格兰、爱尔兰、瑞士和新西兰进行基于案例的全科医生调查。方法评估全科医生对于8例表现为亚临床甲状腺功能减退患者的治疗策略(治疗是/否,起始剂量甲状腺素)。患者的特征如年龄(70岁与85岁),活力状态(充满活力与脆弱)和促甲状腺激素(TSH)浓度(6 m U/L与15 m U/L)均有差异。结果共有526名全科医生参与此项研究(瑞士262名、荷兰129名、德国61名、新西兰31名、英格兰22名、爱尔兰21名,总有效率为19%)。不同国家的治疗策略会有所不同。相比较于来自德国(平均治疗比例为73%)、爱尔兰(平均治疗比例为62%)和瑞士(平均治疗比例为52%)的全科医生,来自荷兰(平均治疗比例为34%)、英格兰(平均治疗比例为40%)和新西兰(平均治疗比例为39%)的全科医生更加不倾向于实施治疗(P=0.05)。总体来讲,全科医生更倾向于对70岁的女性患者实施治疗,而不是85岁的女性患者〔比值比=0.74,95%CI(0.63,0.87)〕。TSH为15 m U/L的患者比TSH为6m U/L的患者更易于得到治疗〔比值比=9.49,95%CI(5.81,15.5)〕。结论全科医生对于不同国家和不同类型的老年亚临床甲状腺功能减退患者的治疗策略有很大差异,而这种差异说明有必要建立新一代基于初级卫生医疗随机临床试验的国际指南。den Elzen WP Lefèbre-van de Fliert AA Virgini V 周淑新 2015中国全科医学2015,18,12:4
2Predictability, Equitability and Adequacy of Post-2012 International Climate Financing Proposals 显示文摘Hof A F Den Elzen M G J Beltran A M 2011Environmental Science & Policy2011,14,6:1
3Wind tunnel flight responses by hymenopterous parasitoidCampoletis sonorensis to cotton cultivars and lines显示文摘G. W. Elzen H. J. Williams S. B. Vinson 1986Entomologia Experimentalis et Applicata1986,,3:1
4Subclinicalhypothyroidism and the risk of coronary heart disease andmorta!ity显示文摘Rodondi N den Elzen WP Bauer DC 2010JAMA2010,304,12:1
5A chimaeric hygromycin resistance gene as a selectable marker in plant cells显示文摘Van Den Elzen P J M Townsend J Lee K Y 1985Plant Molecular Biology1985,5,:1
6Direct screening for high-level expression of an introduced alpha-amylase gene in plants显示文摘Pen J van Ooyen AJ van den Elzen PJ 1992Plant Mol Biol1992,18,6:1
7Apolipoprotein mediated pathways of lipid antigen presentation显示文摘Van den Elzen P Garg S Leon L 2005Nature2005,437,:1
8Strategies for shifting technolog- ical systems显示文摘Schot J R Hoogma B Elzen 1994The case of the Automobile System1994,26,10:1
9Evaluating the Bonn-Marrakesh Agreement显示文摘ELZEN M G J MOOR A P G 2002Climate Policy2002,2,:1
10Impaired drinkingcapacity in patients with functional dyspepsia: intragastric distributionand distal stomach volume显示文摘van den Elzen BD Bennink RJ Holman R 2007Neurogastroenterol Motil2007,19,12:1
11Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contacts显示文摘Scott JA Shewan AM Den Elzen NR 2006Mol Biol Cell2006,17,3:1
12Isolation and identification of cotton synomone mediating searching behaviour by parasitoid Campoletis sonorensis显示文摘Elzen G W Williams H J Vinson S B 1984J Chem Ecol1984,10,8:1
13Cloning and molecular characterization of the chalcone synthase multigene family of Petunia hybrida (V30) 显示文摘Koes R E Spelt C E van den Elzen P J M 1989Gene1989,81,2:1
14Abatement costs of post-Kyoto climate regimes显示文摘 Lucas P van Vuuren D 2005Energy Policy2005,33,:1
15Wind tunnel flight responses by hymenopterous parasitoid Campoletis sonorensis to cotton cultivars and lines显示文摘Elzen G W Williams H J Vinson S B 1986Entomol Exp Appl1986,42,:1
16Comparative flight behavior of parasitoids Campoletis and Microplitis croceipes显示文摘Elzen G W Williams H J Vinson S B Powell J E 1987Entomol Exp Appl1987,45,:1
17Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase 显示文摘den Elzen N Pines J 2001J Cell Biol2001,153,1:1
18Effect of SRT and temperature on biological conversions and the related scum- forming potential显示文摘Halalsheh M Koppes J Den Elzen J 2005Water research2005,39,12:1
19Common but Differentiated Convergence (CDC) : A New Conceptual Approach to the Long-term Climate Policy 显示文摘Hoehen N Elzen M D Weiss M 2006Climate Policy2006,6,:1
20Subclinical hypothyroidism and the risk of coronary heart disease and mortality显示文摘Rodondi N den Elzen WP Bauer DC 2010JAMA2010,304,12:1
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