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| 1 | Superior LSPR substrates based on electromagnetic decoupling for on-a-chip high-throughput label-free biosensing显示文摘Localized surface plasmon resonance(LSPR)biosensing based on supported metal nanoparticles offers unparalleled possibilities for high-end miniaturization,multiplexing and high-throughput label-free molecular interaction analysis in real time when integrated within an opto-fluidic environment.However,such LSPR-sensing devices typically contain extremely large regions of dielectric materials that are open to molecular adsorption,which must be carefully blocked to avoid compromising the device readings.To address this issue,we made the support essentially invisible to the LSPR by carefully removing the dielectric material overlapping with the localized plasmonic fields through optimized wet-etching.The resulting LSPR substrate,which consists of gold nanodisks centered on narrow SiO2 pillars,exhibits markedly reduced vulnerability to nonspecific substrate adsorption,thus allowing,in an ideal case,the implementation of thicker and more efficient passivation layers.We demonstrate that this approach is effective and fully compatible with state-of-the-art multiplexed real-time biosensing technology and thus represents the ideal substrate design for high-throughput label-free biosensing systems with minimal sample consumption. | Srdjan S Aćimović Hana Šípová Gustav Emilsson Andreas B Dahlin Tomasz J Antosiewicz Mikael Käll | 2017 | Light(Science & Applications)2017，6，1： | 3 |
| 2 | Hyperglycaemia and absorption of sulphonylurea drugs显示文摘 | Emilsson H | 1987 | J Chromatogr1987，421，： | 2 |
| 3 | Nocturnal gastroesophageal reflux, lung function and symptoms of obstructive sleep apnea: Results from an epidemiological survey 显示文摘 | Emilsson OI Janson C Benediktsd6ttir B | 2012 | Respir Med2012，106，45： | 1 |
| 4 | Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion显示文摘 | EMILSSON V LIU Y L CAWTHORNE M A | 1997 | Diabetes1997，46，2： | 1 |
| 5 | 显示文摘 | Islam MS Sjoholm A Emilsson V | 2000 | Int J Obes Relat Metab Disord2000，，10： | 1 |
| 6 | The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts 显示文摘 | Lyon HN Emilsson V Hinney A | 2007 | PLoS Genet2007，3，4： | 1 |
| 7 | Increased espression of the uncoupling protein gene inadipose tissue显示文摘 | Emilsson V Hoffstedt J Nyberg | 1998 | Biochem Biophys Res Commun1998，252，2： | 1 |
| 8 | A questionnaire on pelvic floor dysfunction postpartum显示文摘 | Luthander C Emilsson T Ljunggren G | 2011 | Int Urogynecol J2011，22，1： | 1 |
| 9 | Increased monoamine oxidase messenger RNA expression levels in frontal cortex of Alzheimer's disease patients显示文摘 | Emilsson L Saetre P Balciuniene J | 2002 | Neurosci Lett2002，326，1： | 1 |
| 10 | Vegetation development on extensive vegetated green roofs: influence of substrate composition, establishment method and species mix显示文摘 | Emilsson T | 2008 | Ecological Engineering2008，33，： | 1 |
| 11 | A questionnaire on pelvic floor dysfunction postpartum 显示文摘 | Luthander C Emilsson T Ljunggren G | 2011 | Int Urogynecol J2011，22，1： | 1 |
| 12 | The relation between mitral annu- lus motion and ejection fraction: a nonlinear function 显示文摘 | Emilsson K Alam M Wandt B | 2000 | J Am Soc Echocardiogr2000，13，10： | 1 |
| 13 | The relation between ejection fraction and mitral annulus motion before and after direct-current electrical cardioversion显示文摘 | Wandt B | 2000 | Clinical Physiology2000，20，3： | 1 |
| 14 | Personality, adherence,asthma control and health-related quality of life in young adultasthmatics显示文摘 | Axelsson M Emilsson M Brink E | 2009 | Respiratory Medicine2009，103，7： | 1 |
| 15 | Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion显示文摘 | Emilsson V Liu YL Cawthorne MA | 1997 | Diabetes1997，46，2： | 1 |
| 16 | Cognitive behav?iour therapy in medication-treated adults with ADHD and persistent symptoms: a randomized controlled trial显示文摘 | Emilsson B Gudjonsson G Sigurdsson JF | 2011 | BMC Psychiatry2011，11，1： | 1 |
| 17 | The relation between ejection fraction and mitral annulus motion before and after direct- current electrical cardioversion显示文摘 | Emilsson K Wandt B | 2000 | Clinical Physiology2000，20，： | 1 |
| 18 | Vegetation development on extensive vegetated green roofs: influence of substrate composition, establishment method and species mix 显示文摘 | Emilsson T | 2008 | Ecological Engineering2008，33，34： | 1 |
| 19 | Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues显示文摘 | Emilsson V Arch J R De Groot R P | 1999 | FEBS Lett1999，455，12： | 1 |
| 20 | Vegetation development on extensive vegetated green roofs:Influence of substrate composition,establishment method and species mix显示文摘 | Emilsson T | 2008 | Ecological Engineering2008，33，34： | 1 |
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