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| 1 | Hospital readmissions in decompensated cirrhotics: Factors pointing toward a prevention strategy显示文摘AIM To reduce readmissions and improve patient outcomes in cirrhotic patients through better understanding of readmission predictors.METHODS We performed a single-center retrospective study of patients admitted with decompensated cirrhosis from January 1, 2011 to December 31, 2013(n = 222). Primary outcomes were time to first readmission and 30-d readmission rate due to complications of cirrhosis. Clinical and demographic data were collected to help describe predictors of readmission, along with care coordination measures such as post-discharge status and outpatient follow-up. Univariate and multivariateanalyses were performed to describe variables associated with readmission.RESULTS One hundred thirty-two patients(59.4%) were readmitted at least once during the study period. Median time to first and second readmissions were 54 and 93 d, respectively. Thirty and 90-d readmission rates were 20.7 and 30.1 percent, respectively. Predictors of 30-d readmission included education level, hepatic encephalopathy at index, ALT more than upper normal limit and Medicare coverage. There were no statistically significant differences in readmission rates when stratified by discharge disposition, outpatient follow-up provider or time to first outpatient visit.CONCLUSION Readmissions are challenging aspect of care for cirrhotic patients and risk continues beyond 30 d. More initiatives are needed to develop enhanced, longitudinal post-discharge systems. | Siamak M Seraj Emily J Campbell Sarah K Argyropoulos Kara Wegermann Raymond T Chung James M Richter | 2017 | World Journal of Gastroenterology2017，23，37： | 3 |
| 2 | Price drivers and structural breaks in European carbon prices 2005–2007显示文摘 | Emilie Alberola Julien Chevallier Beno??t Chèze | 2007 | Energy Policy2007，，2： | 3 |
| 3 | The effectiveness of interventions to increase physical activity显示文摘 | EMILY B KAHN LEIGH T RAMSEY | 2002 | Am J Pre Med2002，22，4： | 1 |
| 4 | Weather from the stratosphere? 显示文摘 | MARK P B DAVIDW J T EMILY FS | 2003 | Science2003，301，： | 1 |
| 5 | Computer image analysisand classification of giant ragweed seeds显示文摘 | Sako Y Emilie E R Daoust T et a1 | 2001 | Weed Sci2001，49，： | 1 |
| 6 | Using biological net- works to search for interacting loci in genome-wide associa- tion studies显示文摘 | Emily M Mailund T Hein J | 2009 | Eur J Hum Genet2009，17，10： | 1 |
| 7 | erm(B)-Carrying Elements in Tetracycline-Resistant Pneumococci and Correspondence between Tn1545 and Tn6003显示文摘 | Ileana C Emily T Marina M | 2008 | Antimicrob Agents Chemother2008，52，4： | 1 |
| 8 | Effect of sorghum flour composition and particle size on quality properties of gluten-free bread显示文摘 | Emily Frederick T Hanna K Fadi A | 2015 | Food Science&Technology International2015，21，3： | 1 |
| 9 | Chemical composition of dissolved organic matter in agroecosystems : Correlations with soil enzyme activity and carbon and nitrogen mineralization 显示文摘 | Lei T Emily D Wei Shi | 2010 | Applied Soil Ecology2010，46，4： | 1 |
| 10 | Price drivers and structural breaks in European carbon prices2005–200显示文摘 | Emilie Alberola Julien Chevallier Beno t Chèze | 2008 | Energy Policy2008，，78： | 1 |
| 11 | Conserved network of proteins essential for bacterial viability 显示文摘 | Handford JI Ize B Buchanan G Butland GP Greenblatt J Emili A Palmer T | 2009 | Bacteriol2009，191，15： | 1 |
| 12 | Emissions compliances and Carbon Prices under the EU ETS:a country specific analysis of industrial sectors显示文摘 | Emilie Alberola Julien Chevallier Beno t Chèze | 2009 | Journal of Policy Modeling2009，，44： | 1 |
| 13 | Analysis of bacterial diversity in river biofilms using16S rDNA PCR - DGGE methodological settings and fingerprints interpretation 显示文摘 | Emilie L Bénédite L LoYc T H | 2005 | Water Research2005，39，： | 1 |
| 14 | New Synthesis of Benzo furan and Indole Derivatives from 1,1-Dibromo-l-alkenes Using a Tandem Pd-assisted Cyclization-coupling Reaction显示文摘 | Sabine T Emilie M Philippe B | 2004 | Tetrahedron Lett2004，45，： | 1 |
| 15 | Parenting style,depressivesymptoms,and substance use in mexican american adolescents 显示文摘 | EMILY JO ELENA F JEANNEM T | 2013 | Youth Soc2013，45，3： | 1 |
| 16 | Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia显示文摘A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongation and many signal transduction pathways.Identification of new and relevant compounds targeting the FGFR3 signaling pathway is of broad importance for the treatment of ACH,and natural plant compounds are prime drug candidate sources.Here,we found that the phenolic compound(-)-epicatechin,isolated from Theobroma cacao,effectively inhibited FGFR3’s downstream signaling pathways.Transcriptomic analysis in an Fgfr3 mouse model showed that ciliary mRNA expression was modified and influenced significantly by the Indian hedgehog and PKA pathways.(-)-Epicatechin is able to rescue mRNA expression impairments that control both the structural organization of the primary cilium and ciliogenesis-related genes.In femurs isolated from a mouse model(Fgfr3^(Y367C/+))of ACH,we showed that(-)-epicatechin eliminated bone growth impairment during 6 days of ex vivo culture.In vivo,we confirmed that daily subcutaneous injections of(-)-epicatechin to Fgfr3^(Y367C/+) mice increased bone elongation and rescued the primary cilium defects observed in chondrocytes.This modification to the primary cilia promoted the typical columnar arrangement of flat proliferative chondrocytes and thus enhanced bone elongation.The results of the present proof-of-principle study support(-)-epicatechin as a potential drug for the treatment of ACH. | Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet | 2022 | Bone Research2022，10，1： | 1 |
| 17 | Enlarging unilateral breast mass in an adolescent male:an unusual presentation of intraductal papilloma显示文摘 | Emily T Thomas F Peter F | | 0，，01： | 1 |
| 18 | Experimental in-vestigation on the impact of aeration rate and stirrer speed on micro-aerobic batch fermentation 显示文摘 | Emily L W T Nandong J Samyudia Y | 2009 | Journal of Ap- plied Sciences2009，9，17： | 1 |
| 19 | Living with Ma'i Suka: Individual, Familial, Cultural, and Environmental Stress a- mong Patients with Type 2 Diabetes Melliitus and Their Caregivers in American Samoa显示文摘 | Emily E Corabelle T Stephen T | 2008 | Prev Chronic Dis2008，5，3： | 1 |
| 20 | Predator vocalizations affcet foraging trade-offs of Northern cardinals显示文摘 | Stanback M T Emily M P | 2010 | The Wilson journal of Ornithology2010，122，1： | 1 |
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