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4篇 您的检索式：作者名="Emmanuel Hermans"

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		题名	作者	年代	出处	被引量
	1	Fibroadhesive scarring of grafted collagen scaffolds interferes with implant–host neural tissue integration and bridging in experimental spinal cord injury显示文摘Severe traumatic spinal cord injury(SCI)results in a devastating and permanent loss of function,and is currently an incurable condition.It is generally accepted that future intervention strategies will require combinational approaches,including bioengineered scaffolds,to support axon growth across tissue scarring and cystic cavitation.Previously,we demonstrated that implantation of a microporous type-I collagen scaffold into an experimental model of SCI was capable of supporting functional recovery in the absence of extensive implant–host neural tissue integration.Here,we demonstrate the reactive host cellular responses that may be detrimental to neural tissue integration after implantation of collagen scaffolds into unilateral resection injuries of the adult rat spinal cord.Immunohistochemistry demonstrated scattered fibroblast-like cell infiltration throughout the scaffolds as well as the presence of variable layers of densely packed cells,the fine processes of which extended along the graft–host interface.Few reactive astroglial or regenerating axonal profiles could be seen traversing this layer.Such encapsulation-type behaviour around bioengineered scaffolds impedes the integration of host neural tissues and reduces the intended bridging role of the implant.Characterization of the cellular and molecular mechanisms underpinning this behaviour will be pivotal in the future design of collagen-based bridging scaffolds intended for regenerative medicine.	Haktan Altinova Sebastian Hammes Moniek Palm Jose Gerardo-Nava Pascal Achenbach Ronald Deumens Emmanuel Hermans Tobias Fuhrmann Arne Boecker Sabien Geraldine Antonia van Neerven Ahmet Bozkurt Joachim Weis Gary Anthony Brook	2019	Regenerative Biomaterials2019，6，2：	4
	2	Dose–response relationships within the parotid gland after radiotherapy for head and neck cancer显示文摘	Barbara Bussels Annelies Maes Patrick Flamen Philippe Lambin Katrien Erven Robert Hermans Sandra Nuyts Caroline Weltens Silvia Cecere Emmanuel Lesaffre Walter Van den Bogaert	2004	Radiotherapy and Oncology2004，，：	1
	3	Pertussis toxin-sensitive modulation of glutamate transport by endothelin-1 type A receptors in glioma cells显示文摘	Mustapha Najimi Jean-Marie Maloteaux Emmanuel Hermans	2004	BBA - Biomembranes2004，，2：	1
	4	In vitro evidence for impaired neuroprotective capacities of adult mesenchymal stem cells derived from a rat model of familial amyotrophic lateral sclerosis (hSOD1 G93A )显示文摘	Cédric Boucherie Anne-Sophie Caumont Jean-Marie Maloteaux Emmanuel Hermans	2008	Experimental Neurology2008，，2：	1

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