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| 1 | Hepatitis B-related events in autologous hematopoietic stem cell transplantation recipients显示文摘AIM: To investigate the frequency of occult hepatitis B, the clinical course of hepatitis B virus (HBV) reactivation and reverse seroconversion and associated risk factors in autologous hematopoietic stem cell transplantation (HSCT) recipients. METHODS: This study was conducted in 90 patients undergoing autologous HSCT. Occult HBV infection was investigated by HBV-DNA analysis prior to transplantation, while HBV serology and liver function tests were screened prior to and serially after transplantation. HBV-related events including reverse seroconversion and reactivation were recorded in all patients. RESULTS: None of the patients had occult HBV prior to transplantation. Six (6.7%) patients were positivefor HBV surface antigen (HBsAg) prior to transplantation and received lamivudine prophylaxis; they did not develop HBV reactivation after transplantation. Clinical HBV infection emerged in three patients after transplantation who had negative HBV-DNA prior to HSCT. Two of these three patients had HBV reactivation while one patient developed acute hepatitis B. Three patients had anti-HBc as the sole hepatitis B-related antibody prior to transplantation, two of whom developed hepatitis B reactivation while none of the patients with antibody to HBV surface antigen (anti-HBs) did so. The 14 anti-HBs-and/or anti-HBc-positive patients among the 90 HSCT recipients experienced either persistent (8 patients) or transient (6 patients) disappearance of anti-HBs and/or anti-HBc. HBsAg seroconversion and clinical hepatitis did not develop in these patients. Female gender and multiple myeloma emerged as risk factors for loss of antibody in regression analysis (P < 0.05). CONCLUSION: Anti-HBc as the sole HBV marker seems to be a risk factor for reactivation after autologous HSCT. Lamivudine prophylaxis in HbsAg-positive patients continues to be effective. | zcan eneli Zübeyde Nur zkurt Kadir Acar Seyyal Rota Sahika Zeynep Aki Zeynep Arzu Yegin Münci Yagci Seren zenirler Gülsan Türkz Sucak | 2010 | World Journal of Gastroenterology2010，16，14： | 3 |
| 2 | A novel drought-inducible gene,A TAF1,encodes a NAC family protein that negatively regulates the expression of stress-responsive genes in Arabidopsis显示文摘 | LU P L CH EN N Z AN R SU Z QI B S REN F CHEN J WANG X C | 2007 | Plant Molecular Biology2007，63，2： | 1 |
| 3 | Primary adrenal tuberculosis:role of computed tomography and CT-guided biopsy in diagnosis显示文摘 | Liatsikos EN Kalogeropoulou CP Papathanassiou Z | | 0，，： | 1 |
| 4 | -ghrelin, a novel radioligand for localizingGHs orphan receptors in human and rat tissue:up-regulationof receptors with athersclerosis显示文摘 | K atugam pola s D Pallikaros Z d av en p o rt AP | 2001 | Br J Pharmacol2001，134，1： | 1 |
| 5 | P53 overexpression as an indicator of overall survival and response to treatment in osteosarcomas显示文摘 | Papai Z Feja CN Hanna EN | 1997 | Pathol Oncol Res1997，3，1： | 1 |
| 6 | Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo显示文摘 | Shinuel Y W en I Fenghuang Z | 2007 | Blood2007，109，10： | 1 |
| 7 | The use of al- falfa, Medicago sativa as a natural carotenpid source in diets of goldfish, Carassius auratus 显示文摘 | YANAR M ER(~EN Z HUNT A O | 2008 | Aquaculture2008，284，1： | 1 |
| 8 | Vectoral secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells显示文摘 | Unemori EN Bouhana KS Werb Z | 1990 | J Biol Chem1990，265，： | 1 |
| 9 | The role of the extracellu- lar matrix protein mindin in airway response to environmental airways injury显示文摘 | FRUSH S LI Z POTYS EN | 2011 | Environmental Health Perspectives2011，119，10： | 1 |
| 10 | Degree-day formulations and applied in Turkey显示文摘 | Kadioglu M En Z | 1999 | Journal of Applied Meteorology1999，38，6： | 1 |
| 11 | Development of recombinant human epidermal growth factor ( rec-hEGF ) 显示文摘 | Hambali Z Ismail EN Somchit MN | 2009 | ResJIntSt2009，10，1： | 1 |
| 12 | Chemoen zymatic preparative separation of silybins A and B显示文摘 | K(i)en V Ga(z)ák R Purchartová K | | 0，，： | 1 |
| 13 | Hyaluronan Signaling during Ozone-Induced Lung Injury Requires TLR4,MyD88,and TIRAP显示文摘 | Li Z Potts-Kant EN Garantziotis S | | 0，，： | 1 |
| 14 | Type-2 fuzzy modeling for desulphurization of steel process original research article显示文摘 | Fazel Z M H Türks en I B Torabi K O | 2007 | Expert Systems with Applications2007，32，1： | 1 |
| 15 | Myo-cardin sumoylation transactivates cardiogenic genes in pluripotent10T1/2 fibroblasts显示文摘 | Wang J Li A Wang Z Feng X Olson EN Schwartz RJ | 2007 | Mol Cell Biol2007，27，2： | 1 |
| 16 | Influence of inter?mittent loading on SCC behavior for an X70 pipeline steel in a near neutral pH solution显示文摘 | Wang Z Y WangJ Q Han En H Ke W | 2007 | Materials and Corrosion2007，58，8： | 1 |
| 17 | 查看详情显示文摘 | Lu Y D He X Q En Y F Wang X Zhuang Z Q | | 0，，： | 1 |
| 18 | Flavin conlai- ning monooxygenase 3 genetic polymorphisms Glu158Lys and Glu308Gly and their relation to isehemie stroke 显示文摘 | Aysun Ttirkano~lu i~z~ elik Birsen Can Demirdi~en | 2013 | Gene2013，521，： | 1 |
| 19 | Controller area network (CAN) for computer integrated manufacturing systems显示文摘 | Nilüfer ?enes?z Murat Esin | 2004 | Journal of Intelligent Manufacturing2004，，4： | 1 |
| 20 | Inhibition of gastric emptying by acarbose is correlated with GLP-1 response and accompanied by CCK release显示文摘 | En?FY Imeryüz N Akin L | 2001 | Am J Physiol Gastrointest Liver Physiol2001，281，3： | 1 |
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