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7篇 您的检索式：作者名="Eng H Lo"

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		题名	作者	年代	出处	被引量
	1	Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed.	Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost	2019	Stroke & Vascular Neurology2019，4，4：	2
	2	Neurogenesis and apoptotic cell death显示文摘	Moskowitz Micharel A Lo Eng H	2003	Stoke2003，34，2：	1
	3	Mechanisms,challenges and opportunities in stroke 显示文摘	Eng H Lo Turgay Dalkara Michael A Moskowitz	2003	Nat Rev Neurosci2003，4，5：	1
	4	Neurogenesis and apoptotic cell death显示文摘	Moskowitz Michael A Lo Eng H	2003	Stroke2003，34，2：	1
	5	Neurogenesis and apoptotic cell death显示文摘	Moskowitx Michael A Lo Eng H	2003	Stroke2003，34，2：	1
	6	Neurogenesis and apoptotic cell death 显示文摘	Moskowitz MA Lo Eng H	2003	Stroke2003，34，2：	1
	7	Multiphasic roles for matrix metalloproteinases after stroke显示文摘	Anna Rosell Eng H Lo	2008	Current Opinion in Pharmacology2008，，1：	1

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