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| 1 | Striking elevation in incidence and prevalence of inflammatory bowel disease in a province of western Hungary between 1977-2001显示文摘AIM:An investigation into inflammatory bowel disease and colorectal cancer in Veszprem Province was conducted from 1977 to 2001.METHODS: Both hospital and outpatient records were collected and reviewed comprehensively. The majority of patients were followed up regularly.RESULTS:The population of the province was decreased from 386000 to 376000 during the period. Five hundred sixty new cases of ulcerative colitis (UC), 212 of Crohn's disease (CD), and 40 of indeterminate colitis (IC) were diagnosed. The incidence rates increased from 1.66 to 11.01 cases per 100 000 persons for UC, from 0.41 to 4.68 for CD and from 0.26 to 0.74 for IC. The prevalence rate at the end of 2001 was 142.6 for UC and 52.9 cases per 100 000 persons for CD. The peak onset age in UC patients was between 30 and 40 years, in CD between 20 and 30 years. A family history of IBD was present in 3.4% in UC and 9.9% in CD patients.Smoking increased the risk for CD (OR=1.94) while it decreased the risk for UC (OR=0.25). Twelve colorectal carcinomas were observed in this cohort, the cumulative colorectal cancer risk after 10 years in UC was 2%, after 20 years 8.8%, after 30 years 13.3%.CONCLUSION:The incidence and prevalence rates of IBD have increased steadily in Veszprem Province, now equivalent to that in Western European countries. Rapid increase in incidence rates supports a probable role for environmental factors. The rate of colorectal cancers in IBD is similar to that observed in Western countries. | Laszlo Lakatos Gabor Mester Zsuzsanna Erdelyi Mihaly Balogh Istvan Szipocs Gyorgy Kamaras Peter Laszlo Lakatos | 2004 | World Journal of Gastroenterology2004，10，3： | 17 |
| 2 | Perianal disease,small bowel disease,smoking,prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease显示文摘AIM:To assess the combined effect of disease phenotype, smoking and medical therapy [steroid, azathioprine(AZA), AZA/biological therapy] on the probability of disease behavior change in a Caucasian cohort of patients with Crohn's disease(CD).METHODS:Three hundred and forty well-characterized, unrelated, consecutive CD patients were analyzed(M/F:155/185, duration:9.4 ± 7.5 years) with a complete clinical follow-up.Medical records including disease phenotype according to the Montreal classification, extraintestinal manifestations, use of medications and surgical events were analyzed retrospectively.Patients were interviewed on their smoking habits at the time of diagnosis and during the regular follow-up visits.RESULTS:A change in disease behavior was observed in 30.8% of patients with an initially non-stricturing, non-penetrating disease behavior after a mean diseaseduration of 9.0 ± 7.2 years.In a logistic regression analysis corrected for disease duration, perianal disease, smoking, steroid use, early AZA or AZA/ biological therapy use were independent predictors of disease behavior change.In a subsequent Kaplan-Meier survival analysis and a proportional Cox regression analysis, disease location(P = 0.001), presence of perianal disease(P < 0.001), prior steroid use(P = 0.006), early AZA(P = 0.005) or AZA/biological therapy(P = 0.002), or smoking(P = 0.032) were independent predictors of disease behavior change.CONCLUSION:Our data suggest that perianal disease, small bowel disease, smoking, prior steroid use, early AZA or AZA/biological therapy are all predictors of disease behavior change in CD patients. | Peter Laszlo Lakatos Zsofia Czegledi Tamas Szamosi Janos Banai Gyula David Ferenc Zsigmond Tunde Pandur Zsuzsanna Erdelyi Orsolya Gemela Janos Papp Laszlo Lakatos | 2009 | World Journal of Gastroenterology2009，15，28： | 14 |
| 3 | Volume and grain boundary diffusion of implanted ^113Sn in aluminium显示文摘 | ERDELYI G FREITAG K RUMMEL G MEHRER H | 1991 | Applied Physics A: Solids and Surfaces1991，53，4： | 1 |
| 4 | Ambient formaldehyde detection with a laser spectrometer based on difference-frequency generation in PPLN显示文摘 | D. Rehle D. Leleux M. Erdelyi F. Tittel M. Fraser S. Friedfeld | 2001 | Applied Physics B Lasers and Optics2001，，8： | 1 |
| 5 | Homo-and heteroex- change of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system显示文摘 | Sperla G H B Szabo G Erdelyi F | 2003 | Br J Pharrnacol2003，139，3： | 1 |
| 6 | Novel Method for the Dynamic Synthesis of Cam Mechanisms with n Imposed Driving Force Profile显示文摘 | ERDELYI HTALABA D A | 2010 | Proceedings of the Institution of Mechanical Engi- neers2010，224，8： | 1 |
| 7 | Determination of waterwheel alternator steady-state reactances from flux plots显示文摘 | FUNCHS E F ERDELYI E A | 1972 | IEEE Transactions on Pow- er Apparatus and Systems1972，91，6： | 1 |
| 8 | High-speed videotopographic measurement of tear film build-up time显示文摘 | Nemeth J Erdelyi B Csakany B Gatspar P Soumelidis A Kahlesz F | 2002 | Invest Ophthalmol Vis Sci2002，43，6： | 1 |
| 9 | ABCC1 polymorphisms in anthracycline-induced cardiotoxicity in childhood acute lymphoblastic leukaemia显示文摘 | Semsei AF Erdelyi DJ Ungrari I | 2012 | Cell Biol Int2012，36，1： | 1 |
| 10 | Higher Transendental Functions显示文摘 | ERDELYI A MAGNUS W OBERHETTINGER F | 1955 | New york:McGaw-Hill1955，，： | 1 |
| 11 | Virtual prototyping of a car turn-signal switch using haptic feedback 显示文摘 | Hunor Erdelyi Doru Talaba | 2010 | Engineering with Computers2010，26，2： | 1 |
| 12 | Clinical and pathologic features of lineage 2 West Nile virus infections in birds of prey in Hungary 显示文摘 | Erdelyi K Ursu K Ferenczi E | 2007 | Vector Borne Zoonotic Dis2007，7，2： | 1 |
| 13 | In interaction with gender a common CYP3A4 polymorphism may influence the survival rate of chemotherapy for childhood acute lympho- blastic leukemia显示文摘 | Gezsi A Lautner Csorba O Erdelyi D J | 2015 | Pharmacogenomics J2015，15，3： | 1 |
| 14 | Detection of Hepatitis E virus in samples of animal origin collected in Hungary显示文摘 | FORGACH P NOWOTNY N ERDELYI K | 2010 | Vet Microbiol2010，143，： | 1 |
| 15 | Introducing foreign DNA into fish eggs with electroporated sperm as a carter Mol显示文摘 | Muller F Ivices Z Erdelyi F Pappe T | 1992 | Marine Biol Biotech1992，1，： | 1 |
| 16 | Determination of grainboundary diffusion coefficients by Auger electron spectroscopy显示文摘 | Erdelyi Z Girardeaux C Langer G A | 2000 | Applied Surface Science2000，，14： | 1 |
| 17 | The Synthesis of Starch-based Super Absorbent Resin显示文摘 | ERDELYI J | 1969 | Cellul Chem Technol1969，11，5： | 1 |
| 18 | Introduction of foreign genes into fish eggs with electroporated sperm as a carrior显示文摘 | Mueller F Ivics Z Erdelyi F | 1992 | Mol Mar Biol Biotechnol1992，1，： | 1 |
| 19 | Fractional integration and dual integral Equations显示文摘 | Erdelyi A Sneddon I N | 1962 | Can J Math1962，14，4： | 1 |
| 20 | Introducing foreign genes into fish eggs with electroporatd sperm as a cartier显示文摘 | Muller E Ivics Z Erdelyi F | 1992 | Mol Mar Biol Biotech1992，1，： | 1 |
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