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您的检索式：作者名="Eric Leclercq"
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| 1 | Morphing the BlobTree显示文摘 | Antoine Leclercq Samir Akkouche | 2000 | Computer Graphics Forum2000，19，4： | 1 |
| 2 | A randomized double-blind comparison of biventricular versus left ventricular stimulation for cardiac resynchronization therapy: The Biventricular versus Left Univentricular Pacing with ICD Back-up in Heart Failure Patients (B-LEFT HF) trial显示文摘 | Giuseppe Boriani Wolfgang Kranig Erwan Donal Leonardo Calo Michela Casella Nicolas Delarche Ignacio Fernandez Lozano Gerardo Ansalone Mauro Biffi Eric Boulogne Christophe Leclercq | 2010 | American Heart Journal2010，，6： | 1 |
| 3 | Effects of paraprobiotics on bile acid metabolism and liver health in largemouth bass(Micropterus salmoides)fed a cottonseed protein concentrate-based diet显示文摘Cottonseed protein concentrate is a sustainable fishmeal alternative in aquafeed.A 10-week experiment was conducted to investigate the effects of a cottonseed protein concentrate-based diet with and without multi-strain yeast fractions(MsYF)on growth,bile acid metabolism,and health in largemouth bass.Four hundred fish(54.0±0.0 g)were casually distributed into 16 tanks(4 replicates/diet).Fish were fed with 4 iso-nitrogen and iso-energetic diets 3 times daily,including a fishmeal diet(FM),a soy protein concentrate-based diet(SPC;replacing 81%fishmeal protein),a cottonseed protein concentrate-based diet(CPC;replacing 81%fishmeal protein),and a CPC diet supplemented with 800 mg/kg MsYF(CPCY).Results showed that the survival of SPC was the lowest,i.e.,48%,with no apparent diet effect among other treatments;we omitted the SPC in additional analyses.Fish fed cottonseed protein concentrate-based diets showed lower growth than FM(P<0.05).Fish fed CPC showed the highest nuclear dense hepatic phenotypes ratio(50%),followed by CPCY(33%)and FM(17%).Further,dietary CPC increased hepatic total cholesterol and triglyceride levels with concurrently increased cholesterol syn-thesis but decreased triglyceride synthesis-associated transcription levels(P<0.05).Furthermore,di-etary CPC increased bile acid synthesis but decreased bile acid transport-associated transcription levels(P<0.05),and then induced an increment of plasma cholic acid and hepatic chenodeoxycholic acid content and the decrement of genus Romboustia(P<0.05).Regarding the effect of MsYF,fish fed CPCY reduced hepatic lipid accumulation and total plasma bile acid content(P<0.05)compared to CPC,suggesting an improvement in liver health.Also,dietary MsYF could reverse the microbiota community structure showing a similar gut microbial composition to FM.In conclusion,81%of fishmeal protein replaced by cottonseed protein concentrate suppressed growth and liver health,while dietary MsYF might mitigate the negative impact of a high cottonseed protein concentrate level diet on liver functions via gut microbiota regulation. | Xiaoze Xie Xiaofang Liang Hao Wang Qiang Zhu Junjun Wang Ying Chang Eric Leclercq Min Xue Jie Wang | 2023 | Animal Nutrition2023，，2： | 0 |
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