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| 1 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 2 | Unified mechanisms of Ca2 + regulation across the Ca2 + channel family显示文摘 | DEMARIA C D ERICKSON M G | 2003 | Neuron2003，39，6： | 1 |
| 3 | Ther apeutic effects of massage therapy and handling touch on caregivers of patients undergoing autologous hematopoietic stem cell transplant 显示文摘 | Rexilius SJ Mundt C Erickson Megel M | 2002 | Oncol Nurs Forum2002，29，3： | 1 |
| 4 | The ovarian androgen producing cells:a review ofstructure/function relationships显示文摘 | ERICKSON G F MAGOFFIN D A DYER C A etal | 1985 | Endocr Rev1985，6，3： | 1 |
| 5 | WACS--wide-area stability and voltage control system: R g~ D and online demonstration 显示文摘 | TAYLOR C W ERICKSON D C MARTIN K E | 2005 | Proceedings of the IEEE2005，93，5： | 1 |
| 6 | A global model of natural volatile organic compound emission 显示文摘 | Guenther A B Hewitt C N Erickson D | 1995 | Journal of Geophysical Research1995，100，： | 1 |
| 7 | PAH loss during bioremediation of manufactured gas plant site soils显示文摘 | Erickson D C Loehr R C Neuhauser E F | 1993 | Water Res1993，27，5： | 1 |
| 8 | Summer meeting 2007-the problems with fresh produce:an overview显示文摘 | Doyle M P Erickson M C | 2008 | J Appl Microbiol2008，105，： | 1 |
| 9 | Be smart, exercise your heart: exercise effects on brain and cognition 显示文摘 | Hillman C H Erickson K I Kramer A F | 2008 | Neurosci2008，9，1： | 1 |
| 10 | A global mod- el of natural volatile organic compound emissions 显示文摘 | Guenther A Hewitt C N Erickson D | 1995 | Journal of Geophysical Research1995，100，5： | 1 |
| 11 | Problem and pathological gambling are associated with poorer mental and physical health in older adults显示文摘 | ERICKSON L MOLINA C A LADD G T | 2005 | Int J Geriatric Psych2005，20，8： | 1 |
| 12 | Plant enhanced remediation of glycol-based aircraft deicing fluids显示文摘 | GARRISON S DAVIS L C ERICKSON L E | 2001 | Waste Manage2001，5，3： | 1 |
| 13 | 显示文摘 | Halvorson R H Erickson R L Davidson C L | 2003 | Dental Materials2003，19，： | 1 |
| 14 | Soil sickness and its control显示文摘 | Huang H C Chou C H Erickson R S | 2006 | Allelo Pathy J2006，18，： | 1 |
| 15 | Soil sickness and its control 显示文摘 | Huang H C Chou C H Erickson R S | 2006 | Allelopathy Journal2006，18，1： | 1 |
| 16 | Conserving SF6 in magnesium melting operation显示文摘 | ERICKSON S C KING J F | 1998 | Foundry M & T1998，126，6： | 1 |
| 17 | A global model of natural volatile organic compound emissions 显示文摘 | Guenther A B Hewitt C N Erickson D | 1995 | J Geophys Res1995，100，： | 1 |
| 18 | Infection of alfal- fa pollen by sclemtinia sclerotiorum显示文摘 | Huang H C Kokko E G Erickson R S | 1997 | Phytoparasitica1997，25，1： | 1 |
| 19 | The role of mRNA stability and transcription in O6-methylguanine-DNA methyltransferase(MGMT)expression in Mer+ human tumor cells显示文摘 | KROES R A ERICKSON L C | 1995 | Carcinogenesis1995，16，： | 1 |
| 20 | A global model of natural volatile organic compound emissions显示文摘 | GUENTHER A HEWITT C N ERICKSON D | 1995 | Jour- nal o: Geophysical Research1995，100，： | 1 |
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