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| 1 | Video capsule endoscopy vs double-balloon enteroscopy in the diagnosis of small bowel bleeding:A systematic review and metaanalysis显示文摘AIM To compare the diagnostic accuracy of video capsule endoscopy(VCE) and double-balloon enteroscopy(DBE) in cases of obscure gastrointestinal bleeding(OGIB) of vascular origin.METHODS MEDLINE(via PubMed), LILACS(via BVS) and Cochrane/CENTRAL virtual databases were searched for studies dated before 2017. We identified prospective and retrospective studies, including observational, cohort, single-blinded and multicenter studies, comparing VCE and DBE for the diagnosis of OGIB, and data of all the vascular sources of bleeding were collected. All patients were subjected to the same gold standard method. Relevant data were then extracted from each included study using a standardized extraction form. We calculated study variables(sensitivity, specificity, prevalence, positive and negative predictive values and accuracy) and performed a meta-analysis using Meta-Disc software.RESULTS In the per-patient analysis, 17 studies(1477 lesions) were included. We identified3150 exams(1722 VCE and 1428 DBE) in 2043 patients and identified 2248 sources of bleeding, 1467 of which were from vascular lesions. Of these lesions, 864(58.5%) were diagnosed by VCE, and 613(41.5%) were diagnosed by DBE. The pretest probability for bleeding of vascular origin was 54.34%. The sensitivity of DBE was 84%(95%CI: 0.82-0.86; heterogeneity: 78.00%), and the specificity was92%(95%CI: 0.89-0.94; heterogeneity: 92.0%). For DBE, the positive likelihood ratio was 11.29(95%CI: 4.83-26.40; heterogeneity: 91.6%), and the negative likelihood ratio was 0.20(95%CI: 0.15-0.27; heterogeneity: 67.3%). Performing DBE after CE increased the diagnostic yield of vascular lesion by 7%, from 83% to90%.CONCLUSION The diagnostic accuracy of detecting small bowel bleeding from a vascular source is increased with the use of an isolated video capsule endoscope compared with isolated DBE. However, concomitant use increases the detection rate of the bleeding source. | Hélcio Pedrosa Brito Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Wanderley Marques Bernardo Dalton Marques Chaves Rogério Kuga Ethan Dwane Maahs Robson Kiyoshi Ishida Eduardo Turiani Hourneaux de Moura Eduardo Guimaraes Hourneaux de Moura | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，12： | 10 |
| 2 | MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors显示文摘 | Liu Xi Sempere Lorenzo F Ouyang Haoxu Memoli Vincent A Andrew Angeline S Luo Yue Demidenko Eugene Korc Murray Shi Wei Preis Meir Dragnev Konstantin H Li Hua DiRenzo James Bak Mads Freemantle Sarah J Kauppinen Sakari Dmitrovsky Ethan | 2010 | Journal of Clinical Investigation2010，，4： | 3 |
| 3 | Effect of CO2 and steam gasification reactions on the oxy- combustion of pulverized coal char显示文摘 | Ethan S H Christopher R S Manfred G | 2012 | Combustion and Flame2012，159，11： | 1 |
| 4 | Energy and material flow through the urban ecosystem 显示文摘 | Ethan H D Scott E | 2000 | Annual Review Energy Environment2000，25，： | 1 |
| 5 | Retinoid targets in cancer therapy antt cliemoprevention 显示文摘 | Dragnev Konstantin H Petty W Jeffrey Dmitrovsky Ethan | 2003 | Cancer Biology&Therapy2003，2，41： | 1 |
| 6 | Laparoscopic repair of acquired lumbar hernia 显示文摘 | Sakarya A Aydede H Ethan MY | 2003 | Surg Endosc2003，17，9： | 1 |
| 7 | Sodium valproate prophylaxis in childhood migraine 显示文摘 | Serdaroglu G Ethan E Tekgul H | 2002 | Headache2002，42，8： | 1 |
| 8 | Ondansetron, granisetron and dexamethasone compared for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: a randomized placebo-controlled study 显示文摘 | Erhan Y Ethan E Aydede H | 2008 | Surgical Endoscopy2008，22，6： | 1 |
| 9 | Synthetic lubricant basestocks from epoxidized soybean oil and guerbet alcohols显示文摘 | Hwang H Ethan S Z | 2006 | Industrial Crops and Products2006，23，： | 1 |
| 10 | Energy and material flow through the urban ecosystem 显示文摘 | Ethan H Decker Scott Elliott Felisa A | 2000 | Ann Rev Energy Environ2000，，25： | 1 |
| 11 | Mitochondrial H^sub 2^O^sub 2^ emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans显示文摘 | Anderson Ethan J Lustig Mary E Boyle Kristen E Woodlief Tracey L Kane Daniel A Lin Chien-Te Rice Jesse W Kang Li Rabinovitch Peter S Szeto Hazel H Houmard Joseph A Cortright Ronald N Wasserman David H Neufer P Darrell | 2009 | Journal of Clinical Investigation2009，，3： | 1 |
| 12 | Agonistic properties of cannabidiol at 5-HT1a receptors显示文摘 | Ethan BR Andrea B Brian H | 2005 | Neurochem Res2005，30，8： | 1 |
| 13 | Methane reforming kinetics within a Ni-YSZ SOFC anode support显示文摘 | Ethan S H Gaurav K G Zhu H Y | 2005 | Appl Catal A2005，95，1： | 1 |
| 14 | Condition monitoring techniques for electrical equipment-a literature survey显示文摘 | Ethan Song Y H | 2003 | IEEE Transactions on Power Delivery2003，18，1： | 1 |
| 15 | Effect of chromium supplementation on glucose metabolism and lipids显示文摘 | Ethan M Athina Tatsioni Alice H | 2007 | Diabetes Care2007，30，8： | 1 |
| 16 | Ondansetron, granisetron, and dexamethasone compared for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy 显示文摘 | Ethan Y Ethan E Aydede H | 2008 | Surg Endosc2008，22，6： | 1 |
| 17 | Coadministration of telaprevir and transcatheter arterial chemoembolization in hepatitis C virus-associated hepatocellular carcinoma显示文摘The use of directacting antiviral agents (e.g. , telaprevir, boceprevir) has improved response rates in patients with hepatitis C virus (HCV) genotype 1 infections. Substantial number of drug-drug interactions are anticipated with the use of telaprevir, a cytochrome P450 3A and P-glycoprotein substrate and inhibitor. Herein we describe a patient with HCV-associated hepatocellular carcinoma treated simultaneously with a telaprevir-containing regimen and localized chemo-therapy (transcatheter arterial chemoembolization) with doxorubicin. No clinically relevant interactions or adverse events developed while on antiviral therapy. | Harrys A Torres Parag Mahale Ethan D Miller Thein H Oo Catherine Frenette Ahmed O Kaseb | 2013 | World Journal of Hepatology2013，5，6： | 1 |
| 18 | Predicting the single-event error rate of a radiation hardenedby design microprocessor 显示文摘 | Cabanas-Holmen Manuel Cannon Ethan H and Amort Tony | 2011 | IEEE Transactions on NuclearScience2011，58，6： | 1 |
| 19 | A Real- Time Multi- Agent System Architecture for E-Commerce Applications 显示文摘 | Lisa C D Victor F W Lekshmi N Ethan H Oleg U | 2000 | Computer Standards & Interfaces2000，，22： | 1 |
| 20 | Strengths and Weaknesses of Quantum Computing显示文摘 | Bennett Charles H Ethan Bernstein | 1995 | Manuscript1995，51，4： | 1 |
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