|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Preoperative selection of patients with colorectal cancerliver metastasis for hepatic resection显示文摘Surgical resection of colorectal liver metastases(CRLM) has a well-documented improvement in survival. To benefit from this intervention, proper selection of patients who would be adequate surgical candidates becomes vital. A combination of imaging techniques may be utilized in the detection of the lesions. The criteria for resection are continuously evolving; currently, the requirements that need be met to undergo resection of CRLM are: the anticipation of attaining a negative margin(R0 resection), whilst maintaining an adequate functioning future liver remnant. The timing of hepatectomy in regards to resection of the primary remains controversial; before, after, or simultaneously. This depends mainly on the tumor burden and symptoms from the primary tumor. The role of chemotherapy differs according to the resectability of the liver lesion(s); no evidence of improved survival was shown in patients with resectable disease who received preoperative chemotherapy. Presence of extrahepatic disease in itself is no longer considered a reason to preclude patients from resection of their CRLM, providing limited extra-hepatic disease, although this currently is an area of active investigations. In conclusion, we review the indications, the adequate selection of patients and perioperative factors to be considered for resection of colorectal liver metastasis. | Rafif E Mattar Faisal A Al-alem Eve Simoneau Mazen Hassanain | 2016 | World Journal of Gastroenterology2016，22，2： | 13 |
| 2 | Hepatitis B genotypes: Relation to clinical outcome in patients with chronic hepatitis B in Saudi Arabia显示文摘AIM: To identify the most common hepatitis B virus (HBV) genotype in Saudi Arabia, and correlate the prevailing genotypes with the clinical outcome of patients. METHODS: Patients were consecutively recruited from the hepatology clinics of two tertiary care referral cen- ters. Patients were categorized into 4 different groups: group 1, patients with hepatitis B and normal liver en- zymes; group 2, patients with hepatitis B and abnormal liver enzymes but without cirrhosis; group 3, patients with hepatitis B and liver cirrhosis; group 4, patients with hepatitis B and hepatocellular carcinoma. All patients had a positive hepatitis B surface antigen (HBsAg). Ge- notyping of HBV was performed by nested PCR-mediated amplification of the target sequence and hybridization with sequence-specific oligonucleotides. RESULTS: Seventy patients were enrolled in this study. They were predominantly male (72.9%) in their mid- forty’s (mean age 47 years). Forty-nine (70%) patients were hepatitis B envelope antigen (HBeAg) negative. The majority of patients (64%) acquired HBV through unknown risk factors. Hepatitis B genotyping revealed that 57 patients (81.4%) were genotype D, 1 patient (1.4%) had genotype A, 1 patient (1.4%) had geno- type C, and 4 patients (5.7%) had genotype E, while 7 patients (10%) had mixed genotype (4 patients ADG, 1 patient DE, 1 patient DF, and 1 patient ADFG). Based on univariate analysis of genotype D patients, significant predictors of advanced liver disease were age, gender, aspartate transaminase, alanine transaminase, albumin,bilirubin, and alkaline phosphatase (all P < 0.001). In multivariate analysis decreased hemoglobin (r = -0.05; 95% CI: -0.08 to -0.03; P = 0.001) and albumin levels (r = -0.004; 95% CI: -0.007 to -0.001; P = 0.002) were highly significant predictors of advanced liver disease. In patients with HBV genotype D, HBeAg negativity was found to increase across advancing stages of liver dis- ease (P = 0.024). CONCLUSION: This study highlights that the vast ma- jority of Saudi patients with chronic hepatitis B have genotype D. No correlation could be observed between the different genotypes and epidemiological or clinical factors. The relationship between genotype D and HBeAg status in terms of disease severity needs to be further elucidated in larger longitudinal studies. | Ayman A Abdo Badr M Al-Jarallah Faisal M Sanai Ahmad S Hersi Khalid Al-Swat Nahla A Azzam Manal Al-Dukhayil Amira Al-Maarik Faleh Z Al-Faleh | 2006 | World Journal of Gastroenterology2006，12，43： | 7 |
| 3 | Six Minute Walk Test to assess functional capacity in chronic liver disease patients显示文摘AIM: To examine the utility of Six Minute Walk Test (6MWT) in patients with chronic liver disease (CLD). METHODS: Two hundred and fifty subjects between the ages of 18 and 80 (mean 47) years performed 6MWT and the Six Minute Walk Distance (6MWD) was measured. RESULTS: The subjects were categorized into four groups. Group A (n = 45) healthy subjects (control); group B (n = 49) chronic hepatitis B patients; group C (n = 54) chronic hepatitis C patients; group D (n = 98) liver cirrhosis patients. The four groups differed in terms of 6MWDs (P < 0.001). The longest distance walked was 421 ± 47 m by group A, then group B (390 ± 53 m), group C (357 ± 72 m) and group D (306 ± 111 m). The 6MWD correlated with age (r = -0.482, P < 0.01), hemoglobin (r = +0.373, P < 0.001) and albumin (r = +0.311, P < 0.001) levels. The Child-Pugh classification was negatively correlated with the 6MWD in cirrhosis (group D) patients (r = -0.328, P < 0.01). At the end of a 12 mo follow-up period, 15 of the 98 cirrhosis patients had died from disease complications. The 6MWD for the surviving cirrhotic patients was longer than for non-survivors (317 ± 101 vs 245 ± 145 m, P = 0.021; 95% CI 11-132). The 6MWD was found to be an independent predictor of survival (P = 0.024). CONCLUSION: 6MWT is a useful tool for assessing physical function in CLD patients. We suggest that 6MWD may serve as a prognostic indicator in patients with liver cirrhosis. | Hatem F Alameri Faisal M Sanai Manal Al Dukhayil Nahla A Azzam Khalid A Al-Swat Ahmad S Hersi Ayman A Abdo | 2007 | World Journal of Gastroenterology2007，13，29： | 5 |
| 4 | 5-Aminolevulinic acid alleviates herbicide-induced physiological and ultrastructural changes in Brassica napus显示文摘It is well known that application of 5-aminolevulinic acid(ALA) could promote the plant growth under abiotic stress in oilseed rape(Brassica napus L.). However, the specifics of its physiological and ultrastructural regulation under herbicide stress conditions are poorly understood. In the present study, alleviating role of ALA in B. napus was investigated under four levels of herbicide propyl 4-(2-(4,6-dimethoxypyrimidin-2-yloxy) benzylamino) benzoate(ZJ0273)(0, 100, 200 and 500 mg L–1) with or without 1 mg L–1 ALA treated for 48 or 72 h. Results showed that after 48 h of herbicide stress, the growth of rape seedlings was significantly inhibited with the successive increases of the ZJ0273 concentrations from 0 to 500 mg L–1, but this inhibition was obviously alleviated by exogenous application of ALA. However, when treatment time prolonged to 72 h, the recovery effects of ALA could not be evaluated due to the death of plants treated with the highest concentration of ZJ0273(500 mg L-1). Further, the root oxidizability and activities of antioxidant enzymes(superoxide dismutase, peroxidase and ascorbate peroxidase) were dramatically enhanced by the application of 1 mg L–1 ALA under herbicide stress. Therefore, plants treated with ALA dynamically modulated their antioxidant defenses to reduce reactive oxygen species(ROS) accumulation and malondialdehyde(MDA) content induced by herbicide stress. Additionally, exogenously applied ALA improved the ultrastructure's of chloroplast, mitochondria and nucleus, and induced the production of stress proteins. Our results suggest that ALA could be considered as a potential plant growth regulator for the improvement of herbicide tolerance through alleviation of the physiological and ultrastructural changes induced by the herbicide in crop production. | XU Ling Faisal Islam ZHANG Wen-fang Muhammad A Ghani Basharat Ali | 2018 | Journal of Integrative Agriculture2018，17，3： | 2 |
| 5 | Analytical Simulation and PRO- FAT II: A New Methodology and a Computer Automated Tool for Fault Tree Analysis in Chemical Process Industries 显示文摘 | Khan Faisal I Abbasi S A | 2000 | Journal of Hazardous Materials2000，，75： | 1 |
| 6 | Major accidents in process industriesand an analysis of causes and consequences显示文摘 | Khan Faisal I Abbasi S A | 1999 | Journ al of LossPreven-tion in the Process Industries1999，12，5： | 1 |
| 7 | Major accident in process in- dustries and an analysis of causes and consequence 显示文摘 | Khan Faisal I Abbasi S A | 1999 | Journal of Loss Prevention in the Process Industries1999，12，： | 1 |
| 8 | A novel voltage sag source detection method using TFR technique显示文摘 | Mohamed A Shareef H Faisal M F | 2010 | Interna- tional Review of Electrical Engineering2010，5，5： | 1 |
| 9 | A recursive pls-based soft sensor for prediction of the melt index duringgrade change operations in HDPE plant 显示文摘 | FAISAL A SALMAN N YEONG K Y | 2006 | Korean Journalof Chemical Engineering2006，26，1： | 1 |
| 10 | Analysis of single-effect evaporator desalination systems combined with vapor compression heat pumps显示文摘 | FAISAL A J HISHAM E D HISHAM E | 1997 | Desalination1997，114，3： | 1 |
| 11 | Identification of the c-kit gene mutations in biopsy tissues of mammary gland carcinoma tumor显示文摘 | Syed RH Hena N Faisal A | 2012 | J Egypt Natl Cane Inst2012，24，2： | 1 |
| 12 | Engineering properties of Leucaena leucocephala for prevention of slope failure 显示文摘 | Normaniza O Faisal H A Barakbah S S | 2008 | Ecological Engineering2008，32，3： | 1 |
| 13 | Design and evaluation of safety measures using a newly proposed显示文摘 | Faisal I Khana Tahir Husaina S A Abbasib | 2002 | Journal of Loss Prevention in the Process Industries2002，15，3： | 1 |
| 14 | Determi-nants of postoperative visual recovery in suprasellarmeningiomas显示文摘 | Galal A Faisal A Al-Werdany M | 2010 | Acta Neurochir(Wien)2010，152，1： | 1 |
| 15 | Heterogeneous photocatalytic degradation of an anthraquinone and a triphenylmethane dye derivative in aqueous suspensions of semiconductor显示文摘 | Tariq M A Faisal M Saquib M | 2008 | Dyes and Pigments2008，76，2： | 1 |
| 16 | SCAP a new methodology for safety management显示文摘 | Faisal I Khana Tahir Husaina S A Abbasib | 2001 | Journal of Hazardous Materials2001，87，： | 1 |
| 17 | The impact of culture and sociological and psychological issues on Muslim pa- tients with breast cancer in Pakistan显示文摘 | Banning M Hafeez H Faisal S et a/ | 2009 | Cancer Nurs2009，32，4： | 1 |
| 18 | Identification of multiple power quality disturbances using S-transform and rule based classification technique 显示文摘 | Faisal M F Mohamed A | 2009 | Journal ofAppliedSeiences2009，9，15： | 1 |
| 19 | TOPHAZOP: a Knowledge-based Software Tool for Conducting HAZOP in a Rapid, Efficient yet Inexpensive Manner 显示文摘 | Faisal I K Abbasi S A | 1997 | Journal of Loss Prevention in Process Industries1997，10，56： | 1 |
| 20 | Major Accidents in Process Industries and An Analysis of Causes and Consequences显示文摘 | Abbasi S A | 1999 | Journal of Loss Prevention in the Process Industries1999，12，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员