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| 1 | Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC. | James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts | 2013 | World Journal of Gastroenterology2013，19，39： | 9 |
| 2 | Intellectual property rights and economic growth 显示文摘 | Falvey R Foster N Greenway D | 2006 | Review of Development Economics2006，10，4： | 1 |
| 3 | Commercial Policy and IIT显示文摘 | Falvey R E | 1981 | Journal of International Economics1981，11，： | 1 |
| 4 | Bilayer vesicles of amphiphilic cyclodextrins:Host membranes that recognize guest molecules显示文摘 | Falvey P Lim C W Darcy R | 2005 | Chemistry-A European Journal2005，11，4： | 1 |
| 5 | Intellectual property rights and economic growth显示文摘 | FALVEY R FOSTER N GREENAWAY D | 2006 | Review of Development Economics2006，10，4： | 1 |
| 6 | Relative backwardness, absorp- tive capacity and knowledge spillovers 显示文摘 | Falvey R Foster N Greenaway D | 2007 | Economics Letters2007，97，3： | 1 |
| 7 | Commercial policy and intra-industry trade显示文摘 | FALVEY R E | 1981 | Journal of International Economics1981，11，4： | 1 |
| 8 | Relative Backwardness, Absorptive Capability and Knowledge Spillovers 显示文摘 | Falvey R Foster N Greenaway D | 2007 | EconomicsLetters2007，97，7： | 1 |
| 9 | Commercial Policy and Intra-Industry Trade显示文摘 | FALVEY R | 1981 | Joumal of International Economics1981，，11： | 1 |
| 10 | Intellectual property rights and economic growth显示文摘 | FALVEY R E FOSTER N GREENAWAY D | | 0，，04： | 1 |
| 11 | Mergers in open economies显示文摘 | Falvey R | 1998 | The World Economy1998，21，8： | 1 |
| 12 | North-South trade, knowledge spillovers and growth 显示文摘 | Falvey R Foster N Greenaway D | 2002 | Journal of Economic Integration2002，，17： | 1 |
| 13 | Imports, exports, knowledge spillovers and growth显示文摘 | FALVEY R N FOSTER D GREENAWAY | 2004 | Economies Letters2004，85，： | 1 |
| 14 | Commercial Policy and Intra-lndustry Trade显示文摘 | FALVEY R | 1981 | Journal of International Economics1981，，1： | 1 |
| 15 | Intellectual Property Rights and Economic Growth 显示文摘 | R Falvey N Foster D Greenaway | 2006 | Review of Development Economics2006，10，4： | 1 |
| 16 | Imports, Exports, Knowledge Spillovers and Growth 显示文摘 | Falvey R Foster N Greenaway D | 2004 | Economics Letters2004，85，2： | 1 |
| 17 | Northsouth Trade,Knowledge Spillovers and Growth显示文摘 | FALVEY R FOSTER N GREENAWAY D | 2002 | Journal of Economic Integration2002，17，4： | 1 |
| 18 | Tariff reforms with rigid wages显示文摘 | Falvey R Kreickemeier U | | 0，，： | 1 |
| 19 | Intellectual property rights and economic growth显示文摘 | FALVEY R FOSTER N GREENWAY D | 2006 | Review of Development Economics2006，10，4： | 1 |
| 20 | Imports, Exports, Knowledge Spillovers and Growth 显示文摘 | Falvey R Foster N Greenaway D | 2004 | Economic Letters2004，85，2： | 1 |
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