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| 1 | Biologically active phenols from Saussurea medusa 显示文摘 | Fan Chengqi Yue Jianmin | 2003 | Bioorg Med Chem2003,11,: | 1 |
| 2 | Novel alkaloids, paxdaphnines Aand B with unprecedented skeletons from the seeds of Daphniphyllum paxianum显示文摘 | FAN Chengqi YIN Sheng XUE Junjuan | 2007 | Tetrahedron2007,63,1: | 1 |
| 3 | Psoracorylifols A-E, five novel compounds with activity against helicobacterpylon from seeds of Psoralea corylifolia 显示文摘 | Yin Sheng Fan Chengqi Dong Lei | 2006 | Tetrahedron2006,62,11: | 1 |
| 4 | PEG包裹纳米金粒子作为新型CT造影剂的初步探索显示文摘目的探究聚乙二醇包裹纳米金粒子(PEGlatedAuNPs)作为新型CT造影剂的可行性。方法将7个不同浓度的PEGlatedAuNPs与非离子型碘造影剂碘普罗胺(Iopromide)进行体外CT扫描,比较衰减系数和成像能力;通过皮下注入和静脉注射方式进行动物体内CT的扫描,评估体内各脏器的强化特点。结果相同浓度的PEGlatedAuNPs较Iopromide衰减系数高,且随着浓度的增加两者CT值差异越来越大;在皮下形态稳定,能长时间停留而不易被吸收;在SD大鼠体内相容性较好;在体内循环时间长,主要经肝脏代谢。结论PEGlatedAuNPs是一种理想的CT分子显像造影剂。 | 张雅颖 侯雨希 刘日 尹伟 彭雯佳 弓静 FAN Chengqi | 2022 | 生物医学工程学进展2022,43,1: | 1 |
| 5 | A two-year(2020–2021)observation of marine phycotoxins in phytoplankton in typical mariculture areas of East China Sea显示文摘To learn the marine phycotoxins(MPTs)contamination status in mariculture areas in the East China Sea(ECS),from May 2020 to October 2021,80 net-concentrated phytoplankton samples were collected from 12 stations in three typical areas with high incidence of red tides,namely,Gouqi Island,Sandu’ao-Lianjiang,and Zhangzhou-Dongshan Island in ECS,and MPTs of the samples were detected.Six types of toxins were detected in 24 samples from 9 stations.Lipophilic marine toxins(LMTs)were more common and diverse in these areas.Pectenotoxin 2(PTX2)was the main lipophilic marine toxin(LMT)in the concentrated phytoplankton samples and the occurrence showed seasonal differences from north to south.According to the potential risks of pectenotoxin(PTXs)to seafood safety,it is suggested to execute regular monitoring on PTXs in ECS and a mandatory standard should be formulated based on the comprehensive analysis of in-situ monitoring and lab research.Meanwhile,contamination risks of cyclic imine toxins in the north and domoic acid(DA)in the south of ECS should also be paid with attention to.Only 2 paralytic shellfish toxins(PSTs),N-sulfocarbamoyl toxin C2(C2),and decarbamoyl gonyatoxin 3(dcGTX3),were found from spring samples in the north of ECS.As the biggest mussel culture county of China,Gouqi Island showed higher toxin diversity and the toxin detection rate was higher than the other two areas.In Gouqi Island area,PSTs were a serious potential threat in spring,and LMTs instead of PSTs became the main risk in summer-autumn seasons.To ensure the safety of seafood and marine environmental health,it is recommended to conduct long-term targeted tracking and monitoring of MPTs in this and similar mariculture areas. | Xiaoqing TIAN Chengqi FAN Yunyu TANG Haiyan ZHANG Wei KANG Sha CHEN Chongbin LI Ya’nan LU | 2022 | Journal of Oceanology and Limnology2022,40,6: | 1 |
| 6 | Biodiversity and phylogenetic analysis of the gut microbiome of Euphausia superba Dana from the Rose Sea of the Antarctic Ocean显示文摘Metabolites derived from marine symbiotic microorganisms have great potential as lead compounds for the discovery of novel marine drugs. Euphausia superba Dana, which lives in the Antarctic Ocean, is regarded as a new source of marine microbial natural products. However, no studies have examined the biodiversity of the symbiotic intestinal microbiome of E. superba. To address this issue, the species diversity and abundance of the gut microbiome of E. superba Dana from the Rose Sea of the Antarctic Ocean were analyzed by culture-independent high-throughput sequencing and pure culture methods. A comparison with gene databases revealed that the microbiome contained 61 known microbial species and a plethora of uncultivable microorganisms. Additionally, 7% of the species in the microbiome were currently unknown. The microbes belonged to 56 genera, eight of which, including Arthrobacter, Bacillus, Candidatus, Lactococcus, Lysinibacillus, Leuconostoc, Solibacillus, and Vibrio, were dominant, as were Vibrionaceae spp. Moreover, 81 microbial strains were isolated by the pure culture method, and they belonged to 36 genera, including Mobilicoccus, Rhodococcus, Arthrobacter, and Microbacterium. The results obtained by two different methods demonstrate the richness of the microbial biodiversity of the gut microbiome of E. superba, and it also suggests that they have good potential for the discovery of novel marine microbial species. | YUAN Lidong LI Lingzhi TIAN Xiaoqing TANG Yingying FAN Chengqi HUANG Hongliang YANG Qiao | 2016 | Advances in Polar Science2016,27,1: | 1 |