|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comprehensive review of autoantibodies in patients with hyper-IgM syndrome显示文摘Hyper-immunoglobulin M syndrome is an X-linked primary immunodeficiency disease caused by mutations in the CD40 ligand gene.The CD40 ligand has been recently highlighted as playing a key role in the pathogenesis of primary biliary cholangitis.In the present study,we assessed an extensive set of serum autoantibodies in a series of well-defined patients with hyper-immunoglobulin M syndrome.Serum,liver-related and liver-not-related autoantibodies IgG,IgM and IgA were tested by ELISA and standard indirect immunofluorescence in HEp-2 cells in 13 Tunisian patients(8 males and 5 females,aged 1–12 years)with hyper-immunoglobulin M syndrome during 1995–2012 and,as controls,21 age-and gender-matched blood donors.The level of IgM antibody against MIT3 was significantly higher in patients than in controls(35.8 vs 10.7,P=0.002).Half of the hyperimmunoglobulin M syndrome patients were found to be anti-MIT3 IgM positive vs none of the controls(Po0.0001).Twenty-three percent of patients were found to be anti-sp100 antibody positive vs only 0.05%of controls.By immunofluorescence,92.3%of patients were MIT3 IgM positive vs none of the controls.In conclusion,the IgM class of anti-MIT3 antibodies was shown to be present by both ELISA and immunofluorescence in most of the patients with hyper-immunoglobulin M syndrome.The presence of the hallmark of primary biliary cholangitis,a disease where the CD40 ligand is a key player,in an immunodeficiency disease caused by mutations in the CD40 ligand gene is very intriguing and opens new scenarios in understanding the immune pathogenesis of primary biliary cholangitis. | Mohamed-Ridha Barbouche Qubo Chen Marco Carbone Imen Ben-Mustapha Zakera Shums Mehdi Trifa Federica Malinverno Francesca Bernuzzi Haiyan Zhang Nourhen Agrebi Gary L Norman Christopher Chang M Eric Gershwin Pietro Invernizzi | 2018 | Cellular & Molecular Immunology2018，15，6： | 2 |
| 2 | Changes in histone H4 acetyla-tion during in vivo versus in vitro maturation of equine oocytes 显示文摘 | Federica F Valentina L Ghylfene G | 2012 | Basic Science of Reprod Medicine2012，18，5： | 1 |
| 3 | The effect-site concentra- tion of remifentanil blunting cardiovascular responses to tracheal intubation and skin incision during bispectral index-guided pro- pofol anesthesia 显示文摘 | Albertin A Casati A Federica L | 2005 | Anesth Analg2005，101，： | 1 |
| 4 | Identification of chlorogenic acid as a resistance factor for thrips in chrysanthemum 显示文摘 | KIRSTEN A L FEDERICA M YOUNG H C et a l | 2009 | Plant Physiology2009，150，3： | 1 |
| 5 | Development of a gas chromatography/mass spectrometry method to quantify several urinary monohydroxy metabolites of polycyclic aromatic hydrocarbons in occupationally exposed subjects显示文摘 | Campo L Federica R Silvia F | 2008 | Journal of Chromatography2008，，： | 1 |
| 6 | Leukaemia inhibitory factor enhances sheep fertilization in vitro via an influence on the oocyte显示文摘 | Federica L Kazutsugu M | 2006 | Theriogenology2006，，6： | 1 |
| 7 | The introduction of QF - PCR in prenatal diagnosis of fetal aneuploidies:time for reconsideration 显示文摘 | Umberto N Faustina L Federica NI | 2004 | Human Reproduction Update2004，10，6： | 1 |
| 8 | Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via en- hanced cardiac a-kit + cell proliferation and differentiation 显示文摘 | Federica L Antonia G Antonella Z | 2005 | Circ Res2005，97，8： | 1 |
| 9 | The effect-site concentration of remifentanil blunting cardiovascular responses to tracheal intubation and skin incision during Bispectral Index-Guided propofol anesthesia显示文摘 | Albertin A Casati A Federica L | 2005 | Anesth Analg2005，101，1： | 1 |
| 10 | Exogenous high-mobility group box-1 protein induces myocardial regenerationafter infarction via enhanced cardiac C-Kin+cell proliferationand differentiation显示文摘 | Federica L Antonia G Antonella Z | 2005 | Circ Res2005，97，8： | 1 |
| 11 | Somatic stem cell research for neural repair:current evidence and emerging perspectives显示文摘 | STEFANIA C FEDERICA L DIMITRA P | 2004 | J Cell Mol Med2004，8，3： | 1 |
| 12 | The effect-site concentration of remifentanil blunting cardiovascular responses to trachealintubation and skin incision during bispoctral index-guided propofol anesthesia 显示文摘 | Albertin A Casati A Federica L | 2005 | Anesth Analg2005，101，： | 1 |
| 13 | Mackay Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses显示文摘 | Federica S Antonio L Charles R | 1998 | Immunol Today1998，19，12： | 1 |
| 14 | CD1a-binding glycosphingolipids stimulating human autoreactive T-cells:synthesis of a family of sulfatides differing in the acyl chain moiety显示文摘 | FEDERICA C LAURA F GENNARO D L | 2002 | Tetrahedron2002，58，： | 1 |
| 15 | The effect-site concentration of remffentanil blunting cardiovascular responses to tracheal intubation and skin incision during bispectral index-guided propofol anesthesia显示文摘 | Albertin A Casati A Federica L | 2005 | Anesth Analg2005，101，1： | 1 |
| 16 | The effect-site concentration of remifentanil blunting cardiovascular responses to tracheal intubation and skin incision during bispectral index-guided propofol anesthesia 显示文摘 | Albertin A Casati A Federica L | 2005 | Anesth Analg2005，101，： | 1 |
| 17 | The effect-site concentration of renaifentanil blunting cardiovascular responses to tracheal intubation and skin incision during bispectral index-guided pmpofol anesthesia显示文摘 | AlbextinA Casati A Federica L | 2005 | Anesth Analg2005，101，1： | 1 |
| 18 | Biodiversity and potentials of marine-derived microorganisms显示文摘 | Federica S Linda C Ameriga L | 1999 | Biotechnology1999，70，： | 1 |
| 19 | The effect-site concentration of remifentanil blunting cardiovascular responses to tracheal intubation and skin incision during bispectral index-guided propofol anesthesia显示文摘 | Albertin A Casati A Federica L | | 0，，01： | 1 |
| 20 | The Oct4 homologue PouV and Nanog regulate pluripotency in chicken embryonic stem cells显示文摘 | Fabrice L Herve A Federica B | 2007 | Development2007，134，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员