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| 1 | Targeting DNA Double-Strand Breaks with TAL Effector Nucleases显示文摘 | Christian Michelle Cermak Tomas Doyle Erin L Schmidt Clarice Zhang Feng Hummel Aaron Bogdanove Adam J Voytas Daniel F | 2010 | Genetics2010，，2： | 3 |
| 2 | 全颗粒饲料对奶牛生产性能的影响显示文摘饲料中的中性洗涤纤维(NDF)含量和饲料颗粒直径是影响瘤胃功能的重要因素。试验评估了以颗粒饲料为主的奶牛瘤胃健康情况、NDF消化率和生产性能。选取8头荷斯坦母牛(336±30 d,体重346±35 kg),随机分配到交叉重复试验组中,奶牛安置于牛栏,自由采食。试验期为3周,前两周是适应期,最后一周为数据收集期。各组饲粮原料相同,但物理形式不同,分为全混合日粮(TMR)和颗粒料(直径=8 mm)。两组间物理有效NDF(pe NDF)不同,TMR组为39.8%,颗粒料组为11.8%。在试验过程中,干物质采食量(DMI)、饮水量、瘤胃反刍时间、瘤胃温度和pH情况均记录。3周后收集粪样,确定潜在的可消化NDF总消化率(pdNDF)。每阶段结束后计算平均日增重和饲料转化率。颗粒料组的DMI、DMI/体重和饮水量更高。而两组间平均日增重和饲料转化率无显著差异。颗粒料组的瘤胃反刍时间为241 min·d-1低于TMR组的507 min·d-1。饲料的不同物理外形对瘤胃温度、瘤胃pH无显著影响。TMR组的pdNDF总消化率为90.25%高于颗粒料组的86.82%。试验结果表明,动物易接受完整的颗粒饲料,DMI较高,且反刍时间减少,但瘤胃pH无显著变化。TMR组的pdNDF消化率显著增加。尽管两组奶牛在DMI和纤维消化方面表现不同,但总体表现相似,两组饲料的保存时间与其物理形式有关。在短期内,提供能满足NDF需求的完全颗粒饲料可改善瘤胃健康状况和动物生产性能,而较长时间的数据则需要进一步试验。 | Wang J Yang M Cao M Lin Y Che L Q Duraipandiyan V Al-Dhabi N A Fang Z F Xu S Y Feng B Liu G Wu D Bonfante E Palmonari A Mammi L Canestrari G Fustini M Formigoni A | 2016 | 饲料博览2016，0，12： | 2 |
| 3 | Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury显示文摘AIM To investigate the hypothesis that exposure to guanidinoacetate(GAA, a potent methyl-group consumer) either alone or combined with ethanol intake for a prolonged period of time would cause more advanced liver pathology thus identifying methylation defects as the initiator and stimulator for progressive liver damage.METHODS Adult male Wistar rats were fed the control or ethanolLieber De Carli diet in the absence or presence of GAA supplementation. At the end of 6 wk of the feeding regimen, various biochemical and histological analyses were conducted. RESULTS Contrary to our expectations, we observed that GAA treatment alone resulted in a histologically normal liver without evidence of hepatosteatosis despite persistence of some abnormal biochemical parameters. This protection could result from the generation of creatine from the ingested GAA. Ethanol treatment for 6 wk exhibited changes in liver methionine metabolism and persistence of histological and biochemical defects as reported before. Further, when the rats were fed the GAA-supplemented ethanol diet, similar histological and biochemical changes as observed after 2 wk of combined treatment, including inflammation, macroand micro-vesicular steatosis and a marked decrease in the methylation index were noted. In addition, rats on the combined treatment exhibited increased liver toxicity and even early fibrotic changes in a subset of animals in this group. The worsening liver pathology could be related to the profound reduction in the hepatic methylation index, an increased accumulation of GAA and the inability of creatine generated to exert its hepato-protective effects in the setting of ethanol.CONCLUSION To conclude, prolonged exposure to a methyl consumer superimposed on chronic ethanol consumption causes persistent and pronounced liver damage. | Natalia A Osna Dan Feng Murali Ganesan Priya F Maillacheruvu David J Orlicky Samuel W French Dean J Tuma Kusum K Kharbanda | 2016 | World Journal of Gastroenterology2016，22，38： | 2 |
| 4 | Competitive Quenching Fluorescence Immunoassay for Chlorophenols Based on Laser-Induced Fluorescence Detection in Microdroplets 显示文摘 | Nichkova M Feng J Sanchez-Baeza F | 2003 | Anal Chem2003，75，1： | 2 |
| 5 | Seasonal variation of solvent extractable organic compounds in the aerosols in Qingdao, China显示文摘 | Guo Z G Sheng L F Feng J L | 2003 | Atmospheric Environment2003，37，13： | 1 |
| 6 | Impedance specifications for stable DC distributed power systems 显示文摘 | FENG X LIU J LEE F C | 2002 | IEEE Transactions on Power Electronics2002，17，2： | 1 |
| 7 | Modeling ofanisotropic damage and creep deformation in brittle rocks显示文摘 | SHAO J F CHAU K T FENG X T | 2006 | International Journal of Rock Mechanics and Mining Sciences2006，43，4： | 1 |
| 8 | Asymmetric atalytic hydrogenation reactions in super critical carbodioxide显示文摘 | Feng S G Gross M F | 1995 | J Am Chem Soc1995，117，： | 1 |
| 9 | Adsorption of 2,4,6-trinitrotoluene on a novel adsorption material PEI/SiO2 显示文摘 | An F Gao B J Feng X Q | 2009 | Journal of Hazardous Materials2009，166，23： | 1 |
| 10 | Triblock copolymer syntheses of mesoporous silica with periodic 50 to 300 angstrom pores显示文摘 | ZHAO D FENG J HUO Q MELOSH N FREDRICKSON G H CHMELKA B F STUCKY G D | 1998 | Science1998，279，5350： | 1 |
| 11 | Narcissus analysis for cooled staring IR system 显示文摘 | He F Y Cui J C Feng S L | 2007 | SPIE2007，6772，67： | 1 |
| 12 | Seasonal variation of solvent extractable organic compounds in the aerosols in Qingdao, China显示文摘 | Guo Z G Sheng L F Feng J L | 2003 | Atmospheric Environment2003，37，13： | 1 |
| 13 | Bio-assay guided isolation and identication of α-glucosidase inhibitors from the leaves of Aquilaria sinensis显示文摘 | Feng J Yang X W Wang R F | 2011 | Phytochemistry2011，，72： | 1 |
| 14 | Concentration and mode of occurrence of trace elements in marine oil shale from the Bilong Co area,northern Tibet,China显示文摘 | FU X G WANG J ZENG Y H TAN F W FENG X L | | 0，，01： | 1 |
| 15 | 查看详情显示文摘 | Liao Y Wang Y Q Feng X X Wang W C Xu F J Zhang L Q | | 0，，： | 1 |
| 16 | Effect of Bi203 on physical, optical and structural properties of boron silicon bismuthate glasses 显示文摘 | GAO G HU L L FAN H Y WANG G N LI K F FENG S Y FAN S J CHEN H Y | 2009 | Optical Materials2009，32，： | 1 |
| 17 | A note on computational formulas for the Drazin inverse of certain block matrices 显示文摘 | Bu C J Feng C C Dong P F | 2012 | Appl Math Comput2012，38，1： | 1 |
| 18 | Effect of the Woods-Saxon nuclear distribution on the chiral magnetic field in Relativ- istic Heavy-ion Collisions显示文摘 | Mo Y J Feng S Q Shi Y F | 2013 | Physical Review C2013，88，88： | 1 |
| 19 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 20 | Improvement of efficiency and color purity utilizing two-step energy transfer for red organic light-emitting devices显示文摘 | Feng J Li F Cao W | 2002 | Appl Phys Lett2002，81，16： | 1 |
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