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您的检索式：作者名="FENG JingLiang"
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| 1 | The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry显示文摘Since the outbreak of coronavirus disease 2019(COVID-19),it has become a global pandemic.The spike(S)protein of etiologic severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specifically recognizes human angiotensin-converting enzyme 2(hACE2)as its receptor,which is recently identified as an interferon(IFN)-stimulated gene.Here,we find that hACE2 exists on the surface of exosomes released by different cell types,and the expression of exosomal hACE2 is increased by IFNα/β treatment.In particular,exosomal hACE2 can specifically block the cell entry of SARS-CoV-2,subsequently inhibit the replication of SARS-CoV-2 in vitro and ex vivo.Our findings have indicated that IFN is able to upregulate a viral receptor on the exosomes which competitively block the virus entry,exhibiting a potential antiviral strategy. | Junsong Zhang Feng Huang Baijin Xia Yaochang Yuan Fei Yu Guanwen Wang Qianyu Chen Qian Wang Yuzhuang Li Rong Li Zheng Song Ting Pan Jingliang Chen Gen Lu Hui Zhang | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 2 | Quantum optical devices based on four-wave mixing in hot rubidium vapor显示文摘In this paper,we briefly review the recent experimental progresses in quantum optics based on four-wave mixing(FWM) processes in hot rubidium vapor,particularly our two recent experiments in quantum information.We have experimentally produced strong quantum correlations between three bright beams generated by two cascaded FWM processes.The intensity difference squeezing with the cascaded system is enhanced to(-7.0±0.1)d B from the(-5.5±0.1)d B/(4.5±0.1)d B with only one FWM process.Also,this system can be easily extended to multiple modes using multiple FWM processes.Besides,we have also successfully realized a cascade all-optical transistor(AOT),which is driven by a very weak light beam about 800 photons in total.The required probe power for achieving a switching efficiency of 50% can be as low as 180 p W,and it can manipulate a light beam with power of 5.0×106 times more,which proves the cascade of the AOT.Both experiments may find wide applications in quantum information and optical communication. | FANG YaMi QIN ZhongZhong WANG HaiLong CAO LeiMing XIN Jun FENG JingLiang ZHANG WeiPing JING JieTai | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，6： | 0 |
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