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6篇 您的检索式:作者名="FENG Liangdong"
    题名 作者 年代 出处 被引量
1Preparation and adsorption characters of C( II )-imprinted chitosan/ attapulgite polymer显示文摘SHI Yingying ZHANG Qianghua FENG Liangdong 2014Korean Journal of Chemical Engineering2014,31,5:1
2Controllable synthesis of sodalite submicron crystals and microspheres from palygorskile clay using a two-step approach显示文摘Jiang Jinlong Gu Xu Feng Liangdong 2012Powder Technol2012,217,:1
3Dynamic determi-nation of domestic liquefied petroleum gas down to several ppmlevels using a Sr-doped Sn02 thick film gas sensor 显示文摘Feng Liangdong Huang Xingjiu Choi Yangkyu 2006Micro-chimica Acta2006,156,34:1
4Characterization of high-performance exfoliated natural rubber/organoclay nanocomposites显示文摘Li Peiyao Wang Li Song Guojun Yin Lanlan Qi Feng Sun Liangdong 2008Journal of Applied Polymer Science2008,109,:1
5New approaches for developing transient electrochemical multi-component gas sensors显示文摘Zhou Zhongbai Feng Liangdong Liu Wenjun Wu Zhigang 2001Sensors and Actuators2001,76,:1
6Secreted phosphoprotein 1 promotes angiogenesis of glioblastoma through upregulating PSMA expression via transcription factor HIF1α显示文摘Glioblastoma multiforme(GBM)is a highly vascularized malignant brain tumor.Our previous study showed that prostate-specific membrane antigen(PSMA)promotes angiogenesis of GBM.However,the specific mechanism underlying GBM-induced PSMA upregulation remains unclear.In this study,we demonstrate that the GBM-secreted cytokine phosphoprotein 1(SPP1)can regulate the expression of PSMA in human umbilical vein endothelial cells(HUVECs).Our mechanistic study further reveals that SPP1 regulates the expression of PSMA through the transcription factor HIF1α.Moreover,SPP1 promotes HUVEC migration and tube formation.In addition,HIF1α knockdown reduces the expression of PSMA in HUVECs and blocks the ability of SPP1 to promote HUVEC migration and tube formation.We further confirm that SPP1 is abundantly expressed in GBM,is associated with poor prognosis,and has high clinical diagnostic value with considerable sensitivity and specificity.Collectively,our findings identify that the GBM-secreted cytokine SPP1 upregulates PSMA expression in endothelial cells via the transcription factor HIF1α,providing insight into the angiogenic process and promising candidates for targeted GBM therapy.Wenjing Tu Hui Zheng Liangdong Li Changshuai Zhou Mingtao Feng Lei Chen Deheng Li Xin Chen Bin Hao Huaping Sun Yiqun Cao Yang Gao 2023Acta Biochimica et Biophysica Sinica2023,55,3:0
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