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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | N-type emitter surface passivation in c-Si solar cells by means of antireflective amorphous silicon carbide layers显示文摘 | Ferre R Martin I Ortega P | 2006 | Journal of Applied Phycology2006，100，73： | 1 |
| 3 | A heterogeneous modular robotic design for fast response to a diversity of tasks显示文摘 | Baca J Ferre M Aracil R | 2012 | Robotics andAutonomous Systems2012，60，4： | 1 |
| 4 | Platysma Myocutaneous Flap for Reconstruc-tion of Skin Defects in the Head and Neck显示文摘 | Puxeddu R Dennis S Ferreli C | 2008 | Br J Oral Maxillofac Surg2008，46，5： | 1 |
| 5 | Vitamin D down - regulates TRPC6 expression in podocyte injury and proteinuric glo- merular disease 显示文摘 | Sonneveld R Ferr S Hoenderop JGJ | 2013 | The American joumal of pathology2013，182，4： | 1 |
| 6 | Akt and ERK/Nri2 activation by PUFA oxidation- derived aldehydes upregulates FABP4 expression in human macrophages显示文摘 | Lazaro I Ferre R Masana L | 2013 | Atherosclerosis2013，230，2： | 1 |
| 7 | Adrenal cystic lesions: report of 12 surgically treated cases and review of the literature显示文摘 | Bellantone R Ferr ante A Raffaelli M | 1998 | J Endoerinol Invest1998，21，2： | 1 |
| 8 | Magnetization process in nickel and cobalt electrodeposited nanowires显示文摘 | Ferre R Ounadjela K Dubois S | 1997 | Physical Review B1997，56，14： | 1 |
| 9 | Influence of fruit on spur leafphotosynthesis and transpiration of Golden Deli-cious'apple显示文摘 | Curt R R Ferre D C | 1986 | HortScience1986，21，： | 1 |
| 10 | Application of unfold principal component analysis and parallel factor analysis to the exploratory analysis of olive oils by means of excitation-emission matrix显示文摘 | Guimet F Ferre J Boque R | 2004 | Analytica Chimica Acta2004，515，1： | 1 |
| 11 | Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain 显示文摘 | Ferre S Diamond I Goldberg S R | 2007 | Prog Neurobiol2007，83，5： | 1 |
| 12 | Spatial averaging of water content by time domain reflectometry: implications for twinrod probes with and without dielectric coatings 显示文摘 | Ferre P A Rudolph D L Kachanoski R G | 1996 | Water Resour Res1996，32，： | 1 |
| 13 | Magnetization reversal in cobalt and nickel electrodeposited nanowire显示文摘 | Qunadjela K Ferre R Lounil L | 1997 | J Applied Phys1997，81，8： | 1 |
| 14 | Crystalline silicon surface passivation by amorphous silicon carbide flms显示文摘 | VETTER M MARTIN I FERRE R | 2007 | Solar Energy Materials & Solar Cells2007，91，23： | 1 |
| 15 | Redundant regulation of meristem identity and plant architecture by FRUITFULL,APETALA1 and CAU-LIFLOWER显示文摘 | Ferrándiz C Gu Q Martienssen R Yanofsky M F | | 0，，： | 1 |
| 16 | Platysma myocutaneous flap for reconstruction of skin defects in the head and neck显示文摘 | Puxeddu R Dennis s Ferreli C | 2008 | Br J O- ral Maxillofac Surg2008，46，5： | 1 |
| 17 | 显示文摘 | Ferré R Ounadjela K George J M | 1997 | Phys RevB1997，56，14： | 1 |
| 18 | n-type emitter surface passivation in c-Si solar cells by means of antireflective amorphous silicon carbide layers显示文摘 | Ferre R Martin I Ortega P | 2006 | Journal of Applied Physics2006，100，： | 1 |
| 19 | HIV感染者蛋白酶抑制剂相关脂代谢异常受载脂蛋白a5-1131T-〉C基因变量明显影响显示文摘伴随高效抗反转录病毒治疗(包含蛋白酶抑制剂)相关高脂血症能加速动脉粥样硬化的形成。能影响极低密度脂蛋白产生和降解的载脂蛋白A—V(APOA5)基因在蛋白酶抑制剂诱导的高脂血症中起着重要的作用,尤其是在那些发生APOA5-1131T-〉C基因型变化的病人中。作者检测了229名HIV感染者5年脂蛋白变化情况。为了进行统计分析。作者根据服用蛋白酶抑制剂和APOA5—1131T-〉C基因型改变将所有病人进行分类。结果发现HIV感染者的频率是0.08。与普通人群相似。 | Guardiola M Ferre R Salazar J Clin Chem 欧强(摘) 张友祥(校) | 2006 | 世界感染杂志2006，6，6： | 1 |
| 20 | The FRUITFULL MADS-box gene mediates cell differentiation during Arabidopsis fruit development显示文摘 | GuQ Ferrándiz C Yanofsky M F Martienssen R | | 0，，： | 1 |
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