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| 1 | Triglyceride levels and apolipoprotein E polymorphism in patients with acute pancreatitis显示文摘BACKGROUND:Hypertriglyceridemia is an unusual cause of acute pancreatitis and sometimes considered to be an epiphenomenon.This study aimed to investigate the clinical and analytical features and the APOE genotypes in patients with acute pancreatitis and severe hypertriglyceridemia.METHODS:We undertook a one-year,prospective study of patients with acute pancreatitis whose first laboratory analysis on admission to the emergency department included measurement of serum triglycerides.The APOE genotype was determined and the patients answered an established questionnaire within the first 24 hours concerning their alcohol consumption,the presence of co-morbidities and any medications being taken.The patients' progression,etiological diagnosis,hospital stay and clinical and radiological severity were all recorded.RESULTS:Hypertriglyceridemia was responsible for 7 of 133 cases of pancreatitis (5%);the remaining cases were of biliary (53%),idiopathic (26%),alcoholic (11%) or other (5%) origin.Compared with these remaining cases,the patients with hypertriglyceridemia were significantly younger,had more relapses,and more often had diabetes mellitus.They usually consumed alcohol or consumed it excessively on the days before admission.Also,the ε4 allele of the APOE gene was more common in this group (P<0.05).CONCLUSION:One of 20 episodes of acute pancreatitis is caused by hypertriglyceridemia and it is linked to genetic (ε4 allele) and comorbid factors such as diabetes and,especially,alcohol consumption. | Radka Ivanova Susana Puerta Alfonso Garrido Ignacio Cueto Ana Ferro María José Ariza Andrés Cobos Pedro González-Santos Pedro Valdivielso | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，1： | 26 |
| 2 | A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility显示文摘Aromatase activity has commonly been associated with male infertility characterized by testicular dysfunction with low serum testosterone and/or testosterone to estradiol ratio.In this subset of patients,and particularly in those with hypogonadism,elevated levels of circulating estradiol may establish a negative feedback on the hypothalamic–pituitary–testicular axis by suppressing follicle-stimulating hormone(FSH)and luteinizing hormone(LH)production and impaired spermatogenesis.Hormonal manipulation via different agents such as selective estrogen modulators or aromatase inhibitors to increase endogenous testosterone production and improve spermatogenesis in the setting of infertility is an off-label option for treatment.We carried out a systematic review and meta-analysis of the literature of the past 30 years in order to evaluate the benefits of the use of aromatase inhibitors in the medical management of infertile/hypoandrogenic males.Overall,eight original articles were included and critically evaluated.Either steroidal(Testolactone)or nonsteroidal(Anastrozole and Letrozole)aromatase inhibitors were found to statistically improve all the evaluated hormonal and seminal outcomes with a safe tolerability profile.While the evidence is promising,future prospective randomized placebo-controlled multicenter trials are necessary to better define the efficacy of these medications. | Francesco Del Giudice Gian Maria Busetto Ettore De Berardinis Isabella Sperduti Matteo Ferro Martina Maggi Martin S Gross Alessandro Sciarra Michael L Eisenberg | 2020 | Asian Journal of Andrology2020，22，4： | 5 |
| 3 | Phase equilibria in the rare earth metals (R) -rich regions of the R-A1 systems (R = La, Ce, Pr, Nd) 显示文摘 | Saccone A Cardinale A M Delfino S Ferro R | 1996 | Zeitschrift fuer Metallkunde1996，87，2： | 1 |
| 4 | Association between low-grade disseminated intravascular coagulation and endotoxemia in patients with liver cirrhosis显示文摘 | Violi F Ferro D Basili S | 1995 | Gastroenterology1995，109，2： | 1 |
| 5 | Order of events in the yeast secretory pathway 显示文摘 | NOVICK P FERRO S SCHEKMAN R | 1981 | Cell1981，25，2： | 1 |
| 6 | Calomys callosus (Rodentia:Cricetidae) trophoblast cells as host cells to Toxoplasma gondii in early pregnancy显示文摘 | Ferro EA Bevilacqua E Favoreto-Junior S | 1999 | Parasitol Res1999，85，89： | 1 |
| 7 | Hyperfibrinolysis increases the risk of gastrointestinal hemorrhage in patients with advanced cirrhosis显示文摘 | Violi F Ferro D Basili S | 1992 | Hepatology1992，15，4： | 1 |
| 8 | Modelling the size selectivities of a trawl codend and an associated square mesh panel显示文摘 | Zuur G Fryer R J Ferro R S T | 2001 | ICES J Mar Sci2001，58，3： | 1 |
| 9 | Systemic clotting activation by lowgrade endotoxaemia in liver cirrhosis: a potential role for endothelial procoagulant activation显示文摘 | Ferro D Basili S Lattuada A | 1997 | ltal J Gastroenterol Hepatol1997，29，5： | 1 |
| 10 | Inhibition of vascular endothelial growth factor by octreotide in colorectal cancer patients显示文摘 | Cascinu S Del Ferro E Ligi M | 2001 | Cancer Invest2001，19，1： | 1 |
| 11 | Phase equilibria in the rare earth metalls (R)-Rich regions of the R-AI sestems (R= La, Ce, Pr, Nd) 显示文摘 | Saccone A Cardinale A M Delfino S Ferro R | 1996 | Z Metalkde1996，87，2： | 1 |
| 12 | Intraperative detection of disappearing colorectal liver metastases as a predictor of resid- ual disease显示文摘 | Ferro A Langwella S Russolillo N | 2012 | J Gastrointest Surg2012，16，4： | 1 |
| 13 | Physical activity prevents progression for cognitive impairment and vascular dementia显示文摘 | Verdelho A Madureira S Ferro JM | 2012 | Stroke2012，43，12： | 1 |
| 14 | Association between low-grade disseminated intravascular coagulation and endotoxemia in patients with liver cirrhosis显示文摘 | VIOLI F FERRO D BASILI S | 1995 | Thromb Res1995，77，3： | 1 |
| 15 | Recovery from aphasiaand neglect显示文摘 | Ferro JM Mariano G Madureira S | 1999 | Cerebrovasc Dis1999，9，5： | 1 |
| 16 | Hyperfibrinolysis resulting from clotting activation in patients with different degrees of cirrhosis显示文摘 | Violi F Ferro D Basili S | 1993 | Hepatology1993，17，1： | 1 |
| 17 | A follow-up study of cog- nitive impairment due to inferior cap sulargenu infarction 显示文摘 | Madureira S Guerreiro M Ferro JM | 1999 | J Neurol1999，246，9： | 1 |
| 18 | Influence of carbon nanotubes structure on the mechanical behavior of cement composites 显示文摘 | MUSSO S TULLIANI J FERRO ( | 2009 | Composites Science and Technology2009，69，11： | 1 |
| 19 | Simvastatin inhibits the mono cyte ex pression of proin flammatory cytokines in patients with hypercholesterolemia 显示文摘 | Ferro D Parrotto S Basili S | 2000 | Am Coil Cardiol2000，36，2： | 1 |
| 20 | Wear resistant CVD diamond tools for turning of sintered hardmetals 显示文摘 | Belmonte M Ferro P Fernandes A J S | 2003 | Diamond and related materials2003，，12： | 1 |
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