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	题名	作者	年代	出处	被引量
1	Amyloid β and free heme:bloody new insights into the pathogenesis of Alzheimer's disease显示文摘The cerebral formation of Amyloid β(Aβ) is a critical pathological feature of Alzheimer's disease(AD).An accumulation of this peptide as senile plaques(SP) was already reported by Alois Alzheimer,the discoverer of the disease.Yet the exact contribution of Aβ to AD development remains elusive.Moreover,while extensive cerebral Aβ formation leads to fibril formation in many species,AD-like symptoms apparently depend on the highly conserved N-terminal residues R5,Y10 and H13.The amino acids were also shown to lead to the formation of Aβ-heme complexes,which exhibit peroxidase activity in the presence of H_2O_2.Taking together these observations we propose that the formation and enzymatic activity of the named complexes may represent an essential aspect of AD pathology.Furthermore,Aβ is also known to lead to cerebral micro-vessel destruction(CAA) as well as to hemolytic events.Thus we suggest that the Aβ-derived cerebral accumulation of blood-derived free heme represents a likely precondition for the subsequent formation of Aβ-heme complexes.	Jorg Flemmig Marcel Zámocky A Alia	2018	Neural Regeneration Research2018，13，7：	1
2	Serine-proteases as plasminogen activators in terms of fibrinolysis显示文摘	Flemmig M Melzig MF	2012	J Pharm Pharmacol2012，64，：	1
3	Subgingivaldebridement efficacy of glycine powder air polishing显示文摘	Flemmig TF Hetzel M Topoll H	2007	J Periodontol2007，78，6：	1
4	Antimicrobial effects of mechanical debridement显示文摘	GREGOR J. PETERSILKA BENJAMIN EHMKE THOMAS F. FLEMMIG	2002	Periodontology 20002002，，1：	1
5	Human myeloperoxidase in innate and acquired immunity 显示文摘	Arnhold J Flemmig J	2010	Arch Biochem Biophys2010，500，1：	1
6	Randomized con- trolled trial assessing efficacy and safety of glycine powder air polishing in moderate to deep periodontal pockets 显示文摘	Flemmig TF Arushanov D Daubert D et at	2012	J Peri- odontal2012，83，4：	1
7	Oral biofilm-associated diseases: trends and implications for quality of life, systemic health and expenditures显示文摘	Beikler T Flemmig T F	2000	Periodontol2000，，1：	1
8	Role of fibroblast populations in peri-implantltis 显示文摘	Bordin S Flemmig TF Verardi S	2009	Int J Oral Maxillofac Implants2009，24，2：	1
9	A systematic review of efficacy of machine-driven and manual subgingival debridement in the treatment of chronic periodontitis 显示文摘	Tunkel J Heinecke A Flemmig TF	2002	J Clin Periodontol2002，，：	1
10	Implants in the medically compromised patient 显示文摘	Beikler T Flemmig TF	2003	Crit Rev Oral Biol Med2003，14，4：	1
11	Implants the medically compromised patient显示文摘	in Beiker T Flemmig T	2003	Crit Rev Oral Biol Med2003，14，：	1
12	Role of fibroblast populations in peri-implantitis 显示文摘	Bordin S Flemmig TF Verardi S	2009	Int J Oral Maxillofac Implants2009，24，2：	1
13	Randomized control ed trial assessing efficacy and safety of glycine powder air polishing in moderate-to-deep periodontal pockets显示文摘	Flemmig TF Arushanov D Daubert D		0，，04：	1
14	Efficacy and safety of adjunctive local moxifloxacin delivery in the treatment of periodontitis显示文摘	Flemmig TF Petersilka G Volp A	2011	J Periodontol2011，82，1：	1
15	Identification of Actinobacillus actinomycetemcomitans in subgingival plaque by PCR显示文摘	Flemmig TF Rudiger S Hotfmann U	1995	J Clin Microbiol1995，33，12：	1
16	Serine-proteases as plasminogen activators in terms of fibrinolysis显示文摘	Flemmig M Melzig MF	2012	J Pharmacol2012，64，：	1
17	Role of fibroblast populations in peri- implantit/s显示文摘	Bordin S Flemmig TF Verardi S	2009	Int J Oral Maxillofae Implants2009，24，2：	1
18	Antimicrobial efects of me- chanical debridement显示文摘	Petersilka GJ Ehmke B Flemmig TF	2002	Periodontol 20002002，28，1：	1
19	Antimicrobial effects of mechanical debridement 显示文摘	Petersilka GJ Ehmke B Flemmig TF	2002	Periodontol 20002002，28，1：	1
20	Controlled local delivery of tetracycline HCl in the treatment of peri-implant mucosal hyperplasia and mucositis:a controlled ease series显示文摘	Schenk G Flemmig TF Betz T		0，，：	1

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