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	题名	作者	年代	出处	被引量
1	Pharmacological approach to acute pancreatitis显示文摘The aim of the present review is to summarize the current knowledge regarding pharmacological prevention and treatment of acute pancreatitis (AP) based on experimental animal models and clinical trials. Somatostatin (SS) and octreotide inhibit the exocrine production of pancreatic enzymes and may be useful as prophylaxis against Post Endoscopic retrograde cholangiopancreatography Pancreatitis (PEP). The protease inhibitor Gabexate mesilate (GM) is used routinely as treatment to AP in some countries, but randomized clinical trials and a meta-analysis do not support this practice. Nitroglycerin (NGL) is a nitrogen oxide (NO) donor, which relaxes the sphincter of Oddi. Studies show conflicting results when applied prior to ERCP and a large multicenter randomized study is warranted. Steroids administered as prophylaxis against PEP has been validated without effect in several randomized trials. The non-steroidal anti-inflammatory drugs (NSAID) indomethacin and diclofenac have in randomized studies showed potential as prophylaxis against PEP. Interleukin 10 (IL-10) is a cytokine with anti-inflammatory properties but two trials testing IL-10 as prophylaxis to PEP have returned conflicting results. Antibodies against tumor necrosis factor-alpha (TNF-α) have a potential as rescue therapy but no clinical trials are currently being conducted. The antibiotics beta- lactams and quinolones reduce mortality when necrosis is present in pancreas and may also reduce incidence of infected necrosis. Evidence based pharmacological treatment of AP is limited and studies on the effect of potent anti-inflammatory drugs are warranted.	Ulrich Christian Bang Synne Semb Camilla Nφjgaard Flemming Bendtsen	2008	World Journal of Gastroenterology2008，14，19：	10
2	Investigation of the enzymatic activity of the Na + , K + - ATPase via isothermal titration microcalorimetry 显示文摘	RAIMUND N FLEMMING C RONALD J C	2010	Biochimiea et Biophysica Acta2010，，1797：	1
3	Annotated type and effect systems显示文摘	FLEMMING N	1996	ACM Computing Surveys(CSUR)1996，28，2：	1
4	Enzymatic characterization of lipid2based drug delivery systems显示文摘	Helena L W Flemming S N Mattias B	2005	Int J Pharm2005，298，32：	1
5	Serum concentrations of antibodies against vaccine toxoids in children显示文摘	CARSTEN H ESBEN B J FLEMMING N		0，，10：	1
6	Prognosis of hepatocellular carcinoma according to new staging classifications显示文摘	CaselitzM Masche N Flemming P	2004	Dtsch Med Wochenschr2004，129，33：	1
7	Tectonic and eustatic coastal changes during the last 10,000 years derived from archaeological data显示文摘	Flemming N C Webb C O		0，，：	1
8	Gap junctional hemichannel -mediated ATP release and hearing controls in the inner ear显示文摘	Zhao HB Yu N Flemming CR	2005	Proc Natl Acad Sci2005，102，18：	1
9	Gap junctional hemichannel -mediated ATP release and hearing controls in the inner ear 显示文摘	Zhao HB Yu N Flemming CR	2005	Proc Natl Acad Sci2005，102，18：	1
10	Enzymatic characterization of lipid-based drug delivery systems显示文摘	Helena L W Flemming S N Mattias B	2005	Int J Pharm2005，298，2：	1
11	A novel method for sensitive and specific detection of DNA methylation biomarkers based on DNA restriction during PCR cycling显示文摘	Kneip C Schmidt B Fleischhacker M Seegebarth A Lewin J Flemming N etal	2009	Biotechniques2009，47，3：	1
12	Use of a simulation laboratory to taain radiology residents in the management of acute radiologic emergencies显示文摘	Sarwani N Tappouni R Flemming D		0，，2：	1
13	Prognosis of hepatocellular carcinoma according to new staging clas- sifications 显示文摘	Caselitz M Masche N Flemming P	2004	Dtsch Med Wochenschr2004，129，33：	1
14	Prognosis of hepatocellular carcinoma according to new staging classifications显示文摘	Caselitz M Masche N Flemming P	2004	Dtsch Med Wochenschr2004，129，33：	1
15	Prognosis of hepatocellular carcinoma according to new staging classifications显示文摘	Caselitz M Masche N Flemming P	2004	Dtsch Med Wochenschr2004，129，33：	1
16	Microtubule alterationsand mutations induced by desoxyepothilone B:implications fordrug-target interactions显示文摘	VERRILS N M FLEMMING C L LIU M	2003	Chemistry & Biology2003，10，7：	1
17	Monomer composition and sequence of alginates from pseudomonas aeruginosa显示文摘	SCHURKS N WINGENDER J FLEMMING H C	2002	Int J Biol Macromol2002，30，：	1
18	Interaction between alginates and manganese cations : identification of preferred cation binding sites 显示文摘	EMMERICHS N WINGENDER J FLEMMING H C	2004	International Journal of Biological Macromolecules2004，34，：	1
19	Prognosis of hepatocellular carcinoma according to new staging classifications 显示文摘	Caselitz M Mascbe N Flemming P	2004	Dtsch Med Wochenschr2004，129，33：	1
20	Oxygen and renal hemodynamics in the conscious rat 显示文摘	Flemming B Seeliger E Wronski T Steer K Arenz N Persson PB	2000	J Am Soc Nephrol2000，11，1：	1

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