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| 1 | Cross-kingdom inhibition of breast cancer growth by plant miR159显示文摘MicroRNAs (miRNAs ) 是基因表示的批评管理者,并且在优核质的开发,生理学,和疾病施加广泛的影响。并行的高度在植物和动物在 miRNA 生物的续生说和行动的分子的基础被发现。最近的研究有趣地建议导出植物的 miRNAs 的一个潜在的跨王国的行动,通过饮食的吸入,在调整哺乳动物的基因表示。尽管在哺乳动物的标本检测的植物 miRNAs 的来源和范围仍然保持争论,这些起始的研究鼓舞了我们决定植物 miRNAs 是否能在西方的人的 sera 被检测并且这些植物 miRNAs 是否能影响与象癌症那样的人的疾病有关的基因表示和细胞的过程。这里,我们发现西方的施主 sera 包含了植物 miRNA miR159,其在浆液的丰富相反地在病人与乳癌发生和前进被相关。在人的 sera, miR159 主要在细胞外的泡被检测,并且对在 3 ′ 上建议发源植物的 2'-O-methylation 的钠 periodate 氧化抵抗;终端核糖。在乳癌房间然而并非非癌的乳房的上皮的房间,一合成 miR159 模仿能够由指向编码表明抄写因素的 Wnt 的 TCF7 禁止增长,在 MYC 蛋白质层次导致减少。miR159 的口头的管理显著地模仿在老鼠压制了异种皮移植胸肿瘤的生长。这些结果第一次证明植物 miRNA 能在哺乳动物禁止癌症生长。 | Andrew R Chin Miranda Y Fong George Somlo Jun Wu Piotr Swiderski Xiwei Wu Shizhen Emily Wang | 2016 | Cell Research2016，26，2： | 35 |
| 2 | Volumetric Analysis Predicts Hepatic Dysfunction in Patients Undergoing Major Liver Resection显示文摘 | Margo Shoup Mithat Gonen Michael D’Angelica William R Jarnagin Ronald P DeMatteo Lawrence H Schwartz Scott Tuorto Leslie H Blumgart Yuman Fong | 2003 | Journal of Gastrointestinal Surgery2003，，3： | 2 |
| 3 | Perioperative outcomes of major hepatic resections under low central venous pressure anesthesia: blood loss, blood transfusion, and the risk of postoperative renal dysfunction显示文摘 | Jose A Melendez Vittoria Arslan Mary E Fischer David Wuest William R Jarnagin Yuman Fong Leslie H Blumgart | 1998 | Journal of the American College of Surgeons1998，，6： | 2 |
| 4 | Regional brain asymmetries in major depression with or without an anxiety disorder:A quantitative eleetroencephalographie study显示文摘 | BRUDER G E FONG R TENKE C E | 1997 | Biol Psychiatry1997，41，： | 1 |
| 5 | Regional brain asymmetry in major depression with or without an anxiety disorder:A quantitative electroencephalographic study显示文摘 | Fong R Tenke CE | 1997 | Biological Psychiatry1997，41，： | 1 |
| 6 | Predictors and patterns of recurrence after resection of hepatocellular carcinoma显示文摘 | Charles Cha Yuman Fong William R Jarnagin Leslie H Blumgart Ronald P DeMatteo | 2003 | Journal of the American College of Surgeons2003，，5： | 1 |
| 7 | Repetitive segmental structure of the transducin β subunit:homology with the CDC4 gene and identification of related mRNAs显示文摘 | Fong H K Hurley J B Hopkins R S | 1986 | Proc Natl Acad Sci USA1986，83，7： | 1 |
| 8 | Relative informational efi3ciency of cash, futures, and options markets: The case of an emerging market 显示文摘 | Chiang R Fong W M | 2001 | Journal of Banking & Finance2001，，25： | 1 |
| 9 | Simultaneous liver and c, olorectal resections are safe for synchronous colorectal liver metastasis显示文摘 | Martin R Paty P Fong Y | 2003 | J Am Coll Surg2003，197，2： | 1 |
| 10 | Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: Towards targeting of cancer stem cells with phytochemicals显示文摘 | FONG D YEH A NAFTALOVICH R | 2010 | Cancer Letters2010，293，1： | 1 |
| 11 | Rice by-products: comparative extraction and precipitation of nitrogen from us and spanish bran and germ显示文摘 | Betschart A A Fong R Y Saunders R M | 1977 | Journal of Food Science1977，42，4： | 1 |
| 12 | Phase I trialinvolving the pharmacodynamic ( PD) study of circulatingtumour cells, of CP - 7 5 1 8 7 1 , a monoclonal antibody againstthe insulin - like growth factor 1 receptor ( IGF -1R ),with docetaxel ( D) in patients with advanced cancer显示文摘 | ATTARD G FONG P C MOLIFE R | | JC lin Oncol0，22，9： | 1 |
| 13 | Growth,nutrient storage,and release of dissolved organic nitrogen by Enteromorpha intestinalis in response to pulses of nitrogen and phosphorus显示文摘 | FONG P FONG J J FONG C R | 2004 | Aquatic Botany2004，78，： | 1 |
| 14 | Conical score for predicting recurrence after hepatic resection for metastatic colorectal carcinoma,An analysis of 1541 cases显示文摘 | FONG Y FORTNER J SUN R L | 1999 | Ann Surg1999，230，： | 1 |
| 15 | Zinc supplementation decreases hepatic copper accumulation in LEC rat: A model of Wilson' s disease 显示文摘 | Gonzalez B P Nino Fong R Gibson C J | 2005 | Biol Trace Elem Res2005，105，11： | 1 |
| 16 | Low-molecular-weight heparin for the treatment of acute ischemic stroke显示文摘 | Wong KS Yu YL Chan YW Tsoi TH Ahuja AT Chan FL Fong KY Law CB Wong A | 1995 | N Engl Med1995，333，： | 1 |
| 17 | Atomic force microscopystudies of Bowen basin coal macerals显示文摘 | Lawrie G A Gentle I R Fong C | 1997 | Fuel1997，76，1415： | 1 |
| 18 | Nitrogen versus phos- phorous limitation of algal biomass in shallow coastal la- goons显示文摘 | Fong P Zedler J B Donohoe R M | 1993 | Liminol Oeeanogr1993，38，： | 1 |
| 19 | Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states显示文摘 | Fong S S Joyce A R Palsson B O | 2005 | Genome Res2005，15，10： | 1 |
| 20 | Competition with macroalgae and benthic cyanobactenal limits phytoplankton abundance in experimental microcosms显示文摘 | Fong P Donohoe R M Zedler J B | 1993 | Mar Ecol Prog Ser1993，100，： | 1 |
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