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| 1 | Interaction between XRCC1 Polymorphisms and Intake of Long-Term Stored Rice in the Risk of Esophageal Squamous Cell Carcinoma:A Case-Control Study显示文摘Objective This study aimed to explore the roles of three common single nucleotide polymorphisms in the X‐ray repair cross‐complementing group‐1 gene (XRCC1) and of life style factors and their possible interactions in the risk of esophageal squamous cell carcinoma (ESCC) in China.Methods A population‐based case‐control study of 432 cases and 915 controls was conducted in Yangzhong County,Jiangsu Province,China.Subjects were interviewed by trained interviewers using a structured questionnaire that included questions on demographics and life style.XRCC1 genotypes were analyzed using a polymerase chain reaction based restriction fragment length polymorphism (PCR‐RFLP) assay.Unconditional logistic regression analysis was used to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for associations of ESCC with XRCC1 polymorphisms and lifestyle‐related factors.Results Both the drinking of river water and alcohol intake history were significantly associated with an increased risk of ESCC among men with aORs of 4.20 (95% CI:2.90‐6.07) and 2.03 (95% CI:1.43‐2.89),respectively.For women,the corresponding odds ratios were 8.37 (95% CI:5.09‐13.75) for river water drinking and 12.78 (95% CI:2.69‐60.69) for long‐term stored rice intake.After the XRCC1 G28152A polymorphism was adjusted for potential confounders,subjects with GA and AA genotypes had an increased risk for ESCC (aOR:1.21,95% CI:0.93‐1.56),compared with subjects with a GG genotype,and a positive multiplicative interaction between intake of long‐term stored rice and the XRCC1 G28152A polymorphism was observed (P=0.009).Conclusions Our findings suggest that both lifestyle‐related factors,including drinking river water,long‐term stored rice and alcohol intake,and the XRCC1 G28152A polymorphism were possible risk factors for ESCC,and that the XRCC1 G28152A polymorphism modified the effect of long‐term stored rice intake on the risk of ESCC among Chinese people. | YU HongJie FU ChaoWei WANG JianMing XUE HengChuan XU Biao | 2011 | Biomedical and Environmental Sciences2011,24,3: | 2 |
| 2 | High prevalence of hyperglycaemia and the impact of high household income in transforming Rural China 显示文摘 | FU Chaowei CHEN Yue WANG Fadi | 2011 | BMC Public Health2011,11,: | 1 |
| 3 | Polymorphisms of the vascular endothelial growth factor A gene and susceptibility to sporadic brain arteriovenous malformation in a Chinese population显示文摘 | Hongyan Chen Yuxiang Gu Wenting Wu Dan Chen Peiliang Li Weiwei Fan Daru Lu Fan Zhao Nidan Qiao Huijia Qiu Chaowei Fu Ying Mao Yao Zhao | 2010 | Journal of Clinical Neuroscience2010,,4: | 1 |
| 4 | A new DRIE cut-off material in SOG MEMS process显示文摘The silicon on glasses process is a common preparation method of micro-electro-mechanical system inertial devices,which can realize the processing of thick silicon structures.This paper proposes that indium tin oxides(ITO)film can serve as a deep silicon etching cut-off layer because ITO is less damaged under the attack of fluoride ions.ITO has good electrical conductivity and can absorb fluoride ions for silicon etching and reduce the reflection of fluoride ions,thus reducing the foot effect.The removal and release of ITO use an acidic solution,which does not damage the silicon structure.Therefore,the selection of the sacrificial layer has an excellent effect in maintaining the shape of the MEMS structure.This method is used in the preparation of MEMS accelerometers with a structure thickness of 100μm and a feature size of 4μm.The over-etching of the bottom of the silicon structure caused by the foot effect is negligible.The difference between the simulated value and the designed value of the device characteristic frequency is less than 5%.This indicates that ITO is an excellent deep silicon etch stopper material. | Chaowei Si Yingchun Fu Guowei Han Yongmei Zhao Jin Ning Zhenyu Wei Fuhua Yang | 2023 | Journal of Semiconductors2023,44,4: | 0 |
| 5 | Tuning the crystalline and electronic structure of ZrO_(2)via oxygen vacancies and nano-structuring for polysulfides conversion in lithium-sulfur batteries显示文摘The recent emergence of tetragonal phases zirconium dioxide(ZrO_(2))with vacancies has generated significant interest as a highly efficient and stable electrocatalyst with potential applications in trapping polysulfides and facilitating rapid conversion in lithium-sulfur batteries(LSBs).However,the reduction of ZrO_(2)is challenging,even under strong reducing atmospheres at high temperatures and pressures.Consequently,the limited presence of oxygen vacancies results in insufficient active sites and reaction interfaces,thereby hindering practical implementation.Herein,we successfully introduced abundant oxygen vacancies into ZrO_(2)at the nanoscale with the help of carbon nanotubes(CNTs-OH)through hydrogen-etching at lower temperatures and pressures.The introduced oxygen vacancies on ZrO_(2-x)/CNTs-OH can effectively rearrange charge distribution,enhance sulfiphilicity and increase active sites,contributing to high ionic and electronic transfer kinetics,strong binding energy and low redox barriers between polysulfides and ZrO_(2-x).These findings have been experimentally validated and supported by theory calculations.As a result,LSBs assembled with the ZrO_(2-x)/CNTs-OH modified separators demonstrate excellent rate performance,superior cycling stability,and ultra-high sulfur utilization.Especially,at high sulfur loading of 6 mg cm^(-2),the area capacity is still up to 6.3 mA h cm^(-2).This work provides valuable insights into the structural and functional optimization of electrocatalysts for batteries. | Shengnan Fu Chaowei Hu Jing Li Hongtao Cui Yuanyuan Liu Kaihua Liu Yanzhao Yang Meiri Wang | 2024 | Journal of Energy Chemistry2024,88,1: | 0 |