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您的检索式：作者名="Fabio Reale"
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| 1 | Differing Temporal Patterns of Onset in Subgroups of Patients With Intracerebral Hemorrhage显示文摘 | Stefano Passero Fabio Reale Giuseppe Ciacci Ettore Zei | 2000 | Stroke: Journal of the American Heart Association2000，，： | 2 |
| 2 | ^(11)C-PK11195 plasma metabolization has the same rate in multiple sclerosis patients and healthy controls:a cross-sectional study显示文摘^(11)C-PK11195 is a positron emitter tracer used for Positron Emission Tomography(PET)imaging of innate immune cell activation in studies of neuroinflammatory diseases.For the image quantitative analysis,it is necessary to quantify the intact fraction of this tracer in the arterial plasma during imaging acquisition(plasma intact fraction).Due to the complexity and costs involved in this analysis it is important to evaluate the real necessity of individual analysis in each 11C-PK11195 PET imaging acquisition.The purpose of this study is to compare 11CPK11195 plasma metabolization rate between healthy controls and multiple sclerosis(MS)patients and evaluate the interference of sex,age,treatment,and disease phenotype in the tracer intact fraction measured in arterial plasma samples.11C-PK11195 metabolization rate in arterial plasma was quantified by high performance liquid chromatography in samples from MS patients(n=50)and healthy controls(n=23)at 20,45,and 60 minutes after 11C-PK11195 injection.Analyses were also stratified by sex,age,treatment type,and MS phenotype.The results showed no significant differences in the metabolization rate of healthy controls and MS patients,or in the stratified samples.In conclusion,11C-PK11195 metabolization has the same rate in patients with MS and healthy controls,which is not affected by sex,age,treatment,and disease phenotype.Thus,these findings could contribute to exempting the necessity for tracer metabolization determination in all 11C-PK11195 PET imaging acquisition,by using a population metabolization rate average.The study procedures were approved by the Ethics Committee for Research Projects Analysis of the Hospital das Clinicas of the University of Sao Paulo Medical School(approval No.624.065)on April 23,2014. | Aline Morais de Souza Milena Sales Pitombeira Larissa Estessi de Souza Fabio Luiz Navarro Marques Carlos Alberto Buchpiguel Caroline Cristiano Real Daniele de Paula Faria | 2021 | Neural Regeneration Research2021，16，12： | 1 |
| 3 | Three X-ray flares near primary eclipse of the RS CVn binary XY UMa显示文摘We report on an archival X-ray observation of the eclipsing RS CVn binary XY UMa(P_(orb) ≈0.48 d). In two Chandra ACIS observations spanning 200 ks and almost five orbital periods, three flares occurred. We find no evidence for eclipses in the X-ray flux. The flares took place around times of primary eclipse, with one flare occurring shortly(< 0.125 P_(orb)) after a primary eclipse, and the other two happening shortly(< 0.05 P_(orb)) before a primary eclipse. Two flares occurred within roughly one orbital period(?φ≈1.024 P_(orb)) of each other. We analyze the light curve and spectra of the system, and investigate coronal length scales during both quiescence and flares, as well as the timing of the flares. We explore the possibility that the flares are orbit-induced by introducing a small orbital eccentricity, which is quite challenging for this close binary. | Hang Gong Rachel Osten Thomas Maccarone Fabio Reale Ji-Feng Liu Paul A. Heckert | 2016 | Research in Astronomy and Astrophysics2016，16，8： | 0 |
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