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| 1 | 秸秆还田方式对不同土壤条件下玉米苗期生长发育的影响显示文摘为探究不同秸秆还田方式对玉米苗期生长影响的生态生理机制,本试验选择3种土壤类型(黑土、黄土、酸土),设置2个还田方式(秸秆覆盖还田、秸秆混拌还田),以及黑土条件下2种石子处理方式(石子覆盖处理、石子混拌处理),比较处理间苗期地上部、地下部形态以及抗逆性生理指标的变化。结果表明:秸秆还田显著增加了玉米苗期株高、叶面积、干物质重、叶绿素荧光参数、根系长度、根系表面积、根尖数以及根系活跃吸收面积,其中秸秆混拌处理优于秸秆覆盖处理;秸秆还田降低了超氧化物歧化酶、过氧化氢酶活性和丙二醛含量,其中覆盖处理好于混拌处理;尽管黄土与黑土、酸土间肥力具有差异,但秸秆还田效果相同;两种石子处理均抑制根系的生长,在覆盖处理或混拌处理方式下秸秆还田处理均显著好于石子处理,因此,秸秆还田主要通过改变土壤生物化学性质促进根系生长和养分吸收,进而促进地上部的生长。 | 王帅 朱涵宇 杨占惠 姜籽竹 陶雨朝 刘昌壮 Jan M FAHEEM 李明 | 2022 | 生态学杂志2022，41，3： | 7 |
| 2 | Hepatitis C virus and neurological damage显示文摘Chronic hepatitis C virus(HCV) infection exhibits a wide range of extrahepatic complications, affecting various organs in the human body. Numerous HCV patients suffer neurological manifestations, ranging from cognitive impairment to peripheral neuropathy. Overexpression of the host immune response leads to the production of immune complexes, cryoglobulins, as well as autoantibodies, which is a major pathogenic mechanism responsible for nervous system dysfunction. Alternatively circulating inflammatory cytokines and chemokines and HCV replication in neurons is another factor that severely affects the nervous system. Furthermore, HCV infection causes both sensory and motor peripheral neuropathy in the mixed cryoglobulinemia as well as known as an important risk aspect for stroke. These extrahepatic manifestations are the reason behind underlying hepatic encephalopathy and chronic liver disease. The brain is an apt location for HCV replication, where the HCV virus may directly wield neurotoxicity. Other mechanisms that takes place by chronic HCV infection due the pathogenesis of neuropsychiatric disorders includes derangement of metabolic pathways of infected cells, autoimmune disorders, systemic or cerebral inflammation and alterations in neurotransmitter circuits. HCV and its pathogenic role is suggested by enhancement of psychiatric and neurological symptoms in patients attaining a sustained virologic response followed by treatment with interferon; however, further studies are required to fully assess the impact of HCV infection and its specific antiviral targets associated with neuropsychiatric disorders. | shilu mathew muhammed faheem sara m ibrahim waqas iqbal bisma rauff kaneez fatima ishtiaq qadri | 2016 | World Journal of Hepatology2016，8，12： | 3 |
| 3 | Porocarcinoma : a rare sweat gland malignaney显示文摘 | Asghar AH Mahmood H Faheem M | 2009 | J Coll Physicians Surg Pak2009，19，6： | 1 |
| 4 | Characterization of rfsputtered indium tin oxide thin films显示文摘 | Tariq B M Manzoor R A Faheem K A | 2004 | Mater Chem Phys2004，，84： | 1 |
| 5 | Therapeutic effects of20 gray radiotherapy over a week in the management of brain me-tastases显示文摘 | Asghar A H Mahmood H Faheem M | 2009 | J Pak Med Assoc2009，59，5： | 1 |
| 6 | A boundary value problem for functional differential equations of delay type显示文摘 | Rao MRM | 1985 | Math Anal Appl1985，109，1： | 1 |
| 7 | Characterization of if-sputtered indium tin oxide thin films 显示文摘 | TARIQ B M MANZOOR R A FAHEEM K A | 2004 | Mater Chem Phys2004，84，： | 1 |
| 8 | Spider-net within the N6, PVA and PU electrospun nanofiber mats using salt addition: Novel strategy in the eleetrospirming process显示文摘 | Nasser A M B Muzafar A K Faheem A S | 2009 | Polymer2009，50，： | 1 |
| 9 | Spider-net within the N6,PVA and PU electrospun nanofiber mats using saltaddition:novel strategy in the electrospinning process显示文摘 | NASSER B A M MUZAFAR A K FAHEEM A S | 2009 | Polymer2009，，50： | 1 |
| 10 | The effect of vitrification of immature bovine oocytes to the subse- quent in vitro development and gene expression显示文摘 | Faheem M S Baron E Carvalhais I | 2014 | Zygote2014，2610，： | 1 |
| 11 | Multiagent-based security for the wireless LAN显示文摘 | FAHEEM H M | | 0，，02： | 1 |
| 12 | Differences in mean and variability of heart rate and ambulatory rate-pressure product when valsartan or carvedilol is added to lisinopril显示文摘 | Izzo J L Jr Yedlapati S H Faheem S M | 2012 | J Am Soc Hypertens2012，6，6： | 1 |
| 13 | Multiple steady states detection in a packed-bed reactive distillation column using bifurcation analysis 显示文摘 | Ramzan N Faheem M Gani R Witt W | 2010 | Computers & Chemical Engineering2010，34，4： | 1 |
| 14 | Saturated absorption spectroscopy of acetylene gas inside large-core photonic bandgap fiber显示文摘 | Thapa R Knabe K Faheem M | 2006 | Optics Letters2006，31，16： | 1 |
| 15 | Carcinosarcoma of the breast显示文摘 | Abbasi MA Mahmood H Faheem M | 2012 | J Coil Physicians Surg Pak2012，22，5： | 1 |
| 16 | Fabrication of biomimetic placental barrier structures within a microfluidic device utilizing two-photon polymerization显示文摘The placenta is a transient organ,essential for development and survival of the unborn fetus.It interfaces the body of the pregnant woman with the unborn child and secures transport of endogenous and exogenous substances.Maternal and fetal blood are thereby separated at any time,by the so-called placental barrier.Current in vitro approaches fail to model this multifaceted structure,therefore research in the field of placental biology is particularly challenging.The present study aimed at establishing a novel model,simulating placental transport and its implications on development,in a versatile but reproducible way.The basal membrane was replicated using a gelatin-based material,closely mimicking the composition and properties of the natural extracellular matrix.The microstructure was produced by using a high-resolution 3D printing method– the two-photon polymerization(2PP).In order to structure gelatin by 2PP,its primary amines and carboxylic acids are modified with methacrylamides and methacrylates(GelMOD-AEMA),respectively.High-resolution structures in the range of a few micrometers were produced within the intersection of a customized microfluidic device,separating the x-shaped chamber into two isolated cell culture compartments.Human umbilical-vein endothelial cells(HUVEC)seeded on one side of this membrane simulate the fetal compartment while human choriocarcinoma cells,isolated from placental tissue(BeWo B30)mimic the maternal syncytium.This barrier model in combination with native flow profiles can be used to mimic the microenvironment of the placenta,investigating different pharmaceutical,clinical and biological scenarios.As proof-of-principle,this bioengineered placental barrier was used for the investigation of transcellular transport processes.While high molecular weight substances did not permeate,smaller molecules in the size of glucose were able to diffuse through the barrier in a time-depended manner.We envision to apply this bioengineered placental barrier for pathophysiological research,where altered nutrient transport is associated with health risks for the fetus. | Denise Mandt Peter Gruber Marica Markovic Maximillian Tromayer Mario Rothbauer Sebastian Rudi Adam Kratz Syed Faheem Ali Jasper Van Hoorick Wolfgang Holnthoner Severin Mühleder Peter Dubruel Sandra Van Vlierberghe Peter Ertl Robert Liska Aleksandr Ovsianikov | 2018 | International Journal of Bioprinting2018，4，2： | 1 |
| 17 | Molecular genetics o~ human primary microcephaly: an overview显示文摘 | Faheem M Naseer MI Rasool M | 2015 | BMC Med Genomics2015，8，1： | 1 |
| 18 | Sizedependent bending analysis of Kirchhoff nano-plates based on a modified couple-stress theory including surface effects显示文摘 | Shaat M Mahmoud FF Gao XL Faheem AF | 2014 | Intemational Journal of Machanical Sciences2014，，79： | 1 |
| 19 | Evaluating How Well Agent-based IDS Performe显示文摘 | Hegazy I M Faheem H M | 2005 | IEEE Potentials2005，24，2： | 1 |
| 20 | Role of endoscopic ultrasound and cyst fluid tumor markers in diagnosis of pancreatic cystic lesions显示文摘BACKGROUND Pancreatic cystic lesions(PCLs) are common in clinical practice. The accurate classification and diagnosis of these lesions are crucial to avoid unnecessary treatment of benign lesions and missed opportunities for early treatment of potentially malignant lesions.AIM To evaluate the role of cyst fluid analysis of different tumor markers such as cancer antigens [e.g., cancer antigen(CA)19-9, CA72-4], carcinoembryonic antigen(CEA), serine protease inhibitor Kazal-type 1(SPINK1), interleukin 1 beta(IL1-β), vascular endothelial growth factor A(VEGF-A), and prostaglandin E2(PGE2)], amylase, and mucin stain in diagnosing pancreatic cysts and differentiating malignant from benign lesions.METHODS This study included 76 patients diagnosed with PCLs using different imaging modalities. All patients underwent endoscopic ultrasound(EUS) and EUS-fine needle aspiration(EUS-FNA) for characterization and sampling of different PCLs.RESULTS The mean age of studied patients was 47.4 ± 11.4 years, with a slight female predominance(59.2%). Mucin stain showed high statistical significance in predicting malignancy with a sensitivity of 87.1% and specificity of 95.56%. It also showed a positive predictive value and negative predictive value of 93.1% and 91.49%, respectively(P < 0.001). We found that positive mucin stain, cyst fluid glucose, SPINK1, amylase, and CEA levels had high statistical significance(P < 0.0001). In contrast, IL-1β, CA 72-4, VEGF-A, VEGFR2, and PGE2 did not show any statistical significance. Univariate regression analysis for prediction of malignancy in PCLs showed a statistically significant positive correlation with mural nodules, lymph nodes, cyst diameter, mucin stain, and cyst fluid CEA. Meanwhile, logistic multivariable regression analysis proved that mural nodules, mucin stain, and SPINK1 were independent predictors of malignancy in cystic pancreatic lesions.CONCLUSION EUS examination of cyst morphology with cytopathological analysis and cyst fluid analysis could improve the differentiation between malignant and benign pancreatic cysts. Also, CEA, glucose, and SPINK1 could be used as promising markers to predict malignant pancreatic cysts. | Hussein Hassan Okasha Abeer Abdellatef Shaimaa Elkholy Mohamad-Sherif Mogawer Ayman Yosry Magdy Elserafy Eman Medhat Hanaa Khalaf Magdy Fouad Tamer Elbaz Ahmed Ramadan Mervat E Behiry Kerolis Y William Ghada Habib Mona Kaddah Haitham Abdel-Hamid Amr Abou-Elmagd Ahmed Galal Wael A Abbas Ahmed Youssef Altonbary Mahmoud El-Ansary Aml E Abdou Hani Haggag Tarek Ali Abdellah Mohamed A Elfeki Heba Ahmed Faheem Hani M Khattab Mervat El-Ansary Safia Beshir Mohamed El-Nady | 2022 | World Journal of Gastrointestinal Endoscopy2022，14，6： | 1 |
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