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| 1 | 由“到 laparoscopic 外科的桥 stenting ”的设法的尖锐 colorectal 阻塞: 我们的经验显示文摘 AIM: To verify the clinical results of the endoscopic stenting procedure for colorectal obstructions followed by laparoscopic colorectal resection with 'one stage anastomosis'. METHODS: From March 2003 to March 2009 in our surgical department, 48 patients underwent endoscopic stenting for colorectal occlusive lesion: 30 males (62.5%) and 18 females (37.5%) with an age range from 40 years to 92 years (median age 69.5). All patients enrolled in our study were diagnosed with an intestinal obstruction originating from the colorectal tract without bowel perforation signs. Obstruction was primitive colorectal cancer in 45 cases (93.7%) and benign anastomotic stricture in 3 cases (6.3%). RESULTS: Surgical resection was totally laparoscopic in 69% of cases (24 patients) while 17% (6 patients) of cases were video-assisted due to the local extension of cancer with infiltrations of surrounding structures (urinary bladder in 2 cases, ileus and iliac vessels in the others). In 14% of cases (5 patients), resection was performed by open surgery due to the high American Society of Anesthesiologists score and the elderly age of patients (median age of 89 years). We performed a terminal stomy in only 7 patients out of 35, 6 colostomies and one ileostomy (in a total colectomy). In the other 28 cases (80%), we performed bowel anastomosis at the same time as resection, employing a temporary ileostomy only in 5 cases. CONCLUSION: Colorectal stenting transforms an emergency operation in to an elective operation performable in a totally laparoscopic manner, limiting the confection of colostomy with its correlated complications. | Pierfrancesco Bonfante Luigi D’Ambra Stefano Berti Emilio Falco Massimo Vittorio Cristoni Romolo Briglia | 2012 | World Journal of Gastrointestinal Surgery2012,4,12: | 11 |
| 2 | Intravenous immune globulin suppresses angiogenesis in mice and humans显示文摘Human intravenous immune globulin(IVIg),a purified IgG fraction composed of~60%IgG1 and obtained from the pooled plasma of thousands of donors,is clinically used for a wide range of diseases.The biological actions of IVIg are incompletely understood and have been attributed both to the polyclonal antibodies therein and also to their IgG(IgG)Fc regions.Recently,we demonstrated that multiple therapeutic human IgG1 antibodies suppress angiogenesis in a target-independent manner via FcγRI,a high-affinity receptor for IgG1.Here we show that IVIg possesses similar anti-angiogenic activity and inhibited blood vessel growth in five different mouse models of prevalent human diseases,namely,neovascular age-related macular degeneration,corneal neovascularization,colorectal cancer,fibrosarcoma and peripheral arterial ischemic disease.Angioinhibition was mediated by the Fc region of IVIg,required FcγRI and had similar potency in transgenic mice expressing human FcγRs.Finally,IVIg therapy administered to humans for the treatment of inflammatory or autoimmune diseases reduced kidney and muscle blood vessel densities.These data place IVIg,an agent approved by the US Food and Drug Administration,as a novel angioinhibitory drug in doses that are currently administered in the clinical setting.In addition,they raise the possibility of an unintended effect of IVIg on blood vessels. | Reo Yasuma Valeria Cicatiello Takeshi Mizutani Laura Tudisco Younghee Kim Valeria Tarallo Sasha Bogdanovich Yoshio Hirano Nagaraj Kerur Shengjian Li Tetsuhiro Yasuma Benjamin J Fowler Charles B Wright Ivana Apicella Adelaide Greco Arturo Brunetti Balamurali K Ambati Sevim Barbasso Helmers Ingrid E Lundberg Ondrej Viklicky Jeanette HW Leusen J Sjef Verbeek Bradley D Gelfand Ana Bastos-Carvalho Sandro De Falco Jayakrishna Ambati | 2016 | Signal Transduction and Targeted Therapy2016,1,1: | 3 |
| 3 | SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells显示文摘 | De Falco E Porcelli D Torella AR Straino S Iachininoto MG Orlandi A | 2004 | Blood2004,104,12: | 1 |
| 4 | Agrobiodiversi- ty, farm profits and land fragmentation: Evidence from Bulgar- ia显示文摘 | FALCO S D PENOV I ALEKSIEV A | 2010 | Land Use Policy2010,27,3: | 1 |
| 5 | Expression and distribution of notch protein members in human placenta throughout pregnancy显示文摘 | De Falco M Cobellis L Giraldi D | 2007 | Placenta2007,28,23: | 1 |
| 6 | Expression and distribution of notch protein members in human placenta throughout pregnancy显示文摘 | De Falco M Cobellis L Giraldi D | 2007 | Placenta2007,28,2: | 1 |
| 7 | Severe nucleoside-associated lac tic acidosis in human immunodeficiency virus infected patients:report of 12 cases and review of the literature 显示文摘 | Falco V Rodriguez D Ribera E | 2002 | Clin Infect Dis2002,34,6: | 1 |
| 8 | Tailoring the porosity of chemically activated hydrothermal carbons: influence of the precursor and hydrothermal carbonization temperature 显示文摘 | FALCO C MARCO-LOZAR J SALINAS-TORRES D | 2013 | Carbon2013,62,2013: | 1 |
| 9 | Posterior fossa vestibular neurotomy as primary surgical treatment of Meniere's disease: a re-evaluation 显示文摘 | PARESCHI R DESTITO D FALCO RAUCCI A | 2006 | J Laryngol Otol2006,116,13: | 1 |
| 10 | Pharmacologic modulation by cetirizine of some adhesion molecules expression in psoriatic skin lesion显示文摘 | Caproni M Palleschi GM Falcos D | 1995 | Int J Dermatol1995,34,: | 1 |
| 11 | Change detection in VHR images based on morphological attribute profiles 显示文摘 | FALCO N MURA M D BOVOLO F | 2013 | IEEE Geoscience and Remote Sensing Letters2013,10,3: | 1 |
| 12 | SDF-1 involvement in endothelial phenotype and ischemia induced recruitment of bone marrow progenitor cells显示文摘 | De Falco E Porcelli D Torella AR | 2004 | Blood2004,104,12: | 1 |
| 13 | Expression and distribution of notch protein members in human placenta throughout pregnancy 显示文摘 | De Falco M Cobellis L Giraldi D | 2007 | Placenta2007,28,: | 1 |
| 14 | Carbon nanotubes as reinforcement of styrene-butadiene rubber显示文摘 | Falco A D Goyanes S Rubiolo G H | 2007 | Applied Surface Science2007,254,1: | 1 |
| 15 | Facing classification problems with particle swarm optimization 显示文摘 | FALCO D CIOPPA A D TARANTINO E | 2007 | Applied Soft Computing2007,,7: | 1 |
| 16 | SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells 显示文摘 | De Falco E Porcelli D Torella AR | 2004 | Blood2004,104,12: | 1 |
| 17 | Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients:evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity显示文摘 | Pende D Marcenaro S Falco M | 2009 | Blood2009,113,13: | 1 |
| 18 | Char- acterization of a cable - free system based on p - type MOSFET de- tectors for 'in vivo' entrance skin dose measurements in interven- tional radiology显示文摘 | Maria Daniela Falco Marco D Andrea Lidia Strigari | 2012 | Med Phys2012,39,8: | 1 |
| 19 | Phase synchronization approach to construction and analysis of stock correla- tion显示文摘 | Sultornsanee S Radhakrishnan S Falco D | 2011 | Procedia Computer Science2011,6,: | 1 |
| 20 | SDF-1 involvement in endot-helial phenotype and ischemia-induced recruitment of bone marrow p-rogenitor cells显示文摘 | De Falco E Porcelli D Torella AR | 2004 | Blood2004,104,: | 1 |