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| 1 | Use of probiotics for prevention of radiation-induced diarrhea显示文摘AIM: To investigate the efficacy of a high-potency probiotic preparation on prevention of radiation-induced diarrhea in cancer patients. METHODS: This was a double-blind, placebo-controlled trial. Four hundred and ninety patients who underwent adjuvant postoperative radiation therapy after surgery for sigmoid, rectal, or cervical cancer were assigned to either the high-potency probiotic preparation VSL#3 (one sachet t.i.d.,) or placebo starting from the first day of radiation therapy. Efficacy endpoints were incidence and severity of radiation-induced diarrhea, daily number of bowel movements, and the time from the start of the study to the use of loperamide as rescue medication. RESULTS: More placebo patients had radiation-induced diarrhea than VSL#3 patients (124 of 239 patients, 51.8%, and 77 of 243 patients, 31.6%; P < 0.001) and more patients given placebo suffered grade 3 or 4 diarrhea compared with VSL#3 recipients (55.4% and 1.4%, P < 0.001). Daily bowel movements were 14.7 ± 6 and 5.1 ± 3 among placebo and VSL#3 recipients (P < 0.05), and the mean time to the use of loperamide was 86 ± 6 h for placebo patients and 122 ± 8 h for VSL#3 patients (P < 0.001). CONCLUSION: Probiotic lactic acid-producing bacteria are an easy, safe, and feasible approach to protect cancer patients against the risk of radiation-induced diarrhea. | P Delia G Sansotta V Donato P Frosina G Messina C De Renzis G Famularo | 2007 | World Journal of Gastroenterology2007，13，6： | 29 |
| 2 | A patient with cerebral Whipple's disease and a stroke-like syndrome 显示文摘 | Famularo G Minisola G Simone C | 2005 | Scand J Gastroenterol2005，40，： | 1 |
| 3 | A patient with cerebral Whipple's disease and a stroke - like syndrome 显示文摘 | Famularo G Minisola G Simone C | 2005 | Scand J Gastroenterol2005，40，： | 1 |
| 4 | Eosinophilic gastroenteritis in a young man显示文摘 | Famularo G Prantera C Nunnari J | | 0，，： | 1 |
| 5 | Probiotic lactobacilli an innovative tool to correct the malabsorption syndrone of vegetarians显示文摘 | Famularo G De Simone C Pandey V | 2005 | Medical Hypotheses2005，65，6： | 1 |
| 6 | A patient with cerebral Whipple's disease and a stroke-like syndrome显示文摘 | Famularo G Minisola G De Simone C | 2005 | Scand J Gastroenterol2005，40，5： | 1 |
| 7 | Robust non- fragile LQ controllers: the static state feedback case 显示文摘 | Famularo D Dorato P Abdallah C T | 2000 | International Journal of Control2000，73，2： | 1 |
| 8 | Inflammatory bowel disease显示文摘 | Famularo G Trinchieri V De Simone C | | 0，，24： | 1 |
| 9 | Inosine pranobex in the treatment of HIV infection: a review显示文摘 | De Simone C Famularo G Tzantzoglou S | 1991 | Int J Immunopharmacol1991，131，： | 1 |
| 10 | Camitines and its congeners:a metabolic pathway to the regulation of immune response and inflammation显示文摘 | Famularo G De Simone C Trinchieri V | 2004 | Ann N Y Acad Sci2004，1033，： | 1 |
| 11 | Robust non-fragile LQ controllers: the static state feedback case显示文摘 | FAMULARO D DORATO P ABDALLAH C T | 1998 | International Journal of Control1998，，： | 1 |
| 12 | Robust non-fragile LQ controllers: the static state feedback case 显示文摘 | FAMULARO D DORATO P ABDALLAH C T | 2000 | Int J Control2000，73，2： | 1 |
| 13 | Detection of anti-erythropoietin antibodies in haemodialysis patients treated with recombinant human erythropoietin 显示文摘 | CASTELLI G FAMULARO A SEMINO C | 2000 | Pharmacol Res2000，41，3： | 1 |
| 14 | Pneumonia and sepsis caused by Gemella morbiUorum: an unusual association显示文摘 | Famularo G De Simone C Minisola G | 2006 | Intern Med2006，45，21： | 1 |
| 15 | Carnitine stands on its own in HIV infection treatment显示文摘 | Famularo G De Simone C Cifone G | 1999 | Archives of Internal Medicine1999，159，10： | 1 |
| 16 | Thromholysis enters the racea new era for acute ischemic stroke显示文摘 | Famularo C Polchi S Panegrossi A | 1998 | Eur J Emerg Med1998，5，2： | 1 |
| 17 | Eosinophilic gastroenteritis in a young man显示文摘 | Famularo G Prantera C Nunnari J | | 0，，： | 1 |
| 18 | Carnitines and its congeners:a metabolic pathway to the regulation of immune response and inflammation显示文摘 | FAMULARO G DE SIMONE C TRINCHIERI V | 2004 | Ann N Y Acad Sci2004，1033，： | 1 |
| 19 | Robust non- fragile LQ controllers: the static feedback case 显示文摘 | Famularo D Dorato P Abdallah C T | 2000 | International Journal of Control2000，73，2： | 1 |
| 20 | Detection of anti-erythropoictin antibodies in haemodialysis patients treated with recombinant human-erythropoietin 显示文摘 | Castelli G Famularo A Semino C | 2000 | Pharmacological Research2000，41，3： | 1 |
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