|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 2 | Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications 显示文摘 | Fang ZY Prins JB Marwick TH | 2004 | Endocrine reviews2004，25，4： | 1 |
| 3 | Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications显示文摘 | FANG ZY PRINS JB MARWICK TH | 2004 | Endocr Rev2004，25，4： | 1 |
| 4 | Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic α, β-unsaturated esters显示文摘 | Shie JJ Fang JM Kuo TH | 2005 | Bioorg Med Chem2005，13，17： | 1 |
| 5 | Relationship between longitudinal and radial contractility in subclinical diabetic heart disease显示文摘 | Fang ZY Leano R Marwick TH | 2004 | Clin Sci2004，106，1： | 1 |
| 6 | The effect of perineural invasion on overall survival in patients with gastric carcinoma显示文摘 | Luo TH Fang GE Bi JW | | 0，，07： | 1 |
| 7 | Diabetic cardiomyopathy : evidence, mecha- nisms, and therapeutic implications 显示文摘 | Fang ZY Prins JB Marwick TH | 2004 | Endocr Rev2004，25，4： | 1 |
| 8 | Diabetie cardiomyopathy: evidence, mechanisms, and therapeutic implications显示文摘 | FANG ZY PRINS JB TMARWICK TH | 2004 | Endocrine Reviews2004，25，4： | 1 |
| 9 | Electron paramagnetic resonance characterization of aluminum ion implantation-induced defects in 4H-SiC显示文摘Deep-level defects in silicon carbide(SiC)are critical to the control of the performance of SiC electron devices.In this paper,deep-level defects in aluminumion-implanted 4H-SiC after high-temperature annealingwere studied using electron paramagnetic resonance(EPR)spectroscopy at temperatures of 77 K and 123 K under different illumination conditions.Results showed that the main defect in aluminum ion-implanted 4H-SiC was the positively charged carbon vacancy(VC+),and the higher the doping concentration was,the higher was the concentration of VC+.Itwas found that the type of material defectwas independent of the doping concentration,although more VC+defects were detected during photoexcitation and at lower temperatures.These results should be helpful in the fundamental research of p-type 4H-SiC fabrication in accordance with functional device development. | Xiuhong Wang Zongwei Xua Mathias Rommel Bing Dong Le Song Clarence Augustine TH Tee Fengzhou Fang | 2019 | Nanotechnology and Precision Engineering2019，2，4： | 1 |
| 10 | Relationship between longitudinal and radial contractility in subclinical diabetic heart disease 显示文摘 | ] Fang ZY Leano R Marwick TH | 2004 | Clin Sci (Lond)2004，106，1： | 1 |
| 11 | Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications 显示文摘 | Fang ZY Prins JB Marwick TH | 2004 | Endocr Rev2004，25，4： | 1 |
| 12 | Association of severe coronary stenosis with subclinical left ventrieular dysfunction in the absence of infarction显示文摘 | Yuda S Fang ZY Marwick TH | 2003 | J Am Soc Echocardiogr2003，16，11： | 1 |
| 13 | Mechanisms of exercise training in patients with heart failure显示文摘 | Fang ZY Marwick TH | 2003 | American Heart Journal2003，145，： | 1 |
| 14 | Peritoneal infusion with cold saline decreased postoperative intra-abdominal adhesion fornation显示文摘 | Fang CC Chou TH Lin GS | | 0，，04： | 1 |
| 15 | Diabetic cardiomyopathy: evi- dence, mechanisms, and therapeutic implications显示文摘 | Fang ZY Prins JB Marwiek TH | 2004 | Endocr Rev2004，25，2： | 1 |
| 16 | Body-mass index and cancer mortality in the Asia-Pacific Cohort Studies Collaboration: pooled analyses of 424,519 participants显示文摘 | Parr CL Batty GD Lam TH Barzi F Fang X Ho SC Jee SH AnsaryMoghaddam A Jamrozik K Ueshima H Woodward M Huxley RR | 2010 | Lancet Oncol2010，11，8： | 1 |
| 17 | An observational study of ex- tracorporeal CPR for in-hospital cardiac arrest secondary to myo- cardial infarction 显示文摘 | Chou TH Fang CC Yen ZS | 2014 | Emerg Med J2014，31，6： | 1 |
| 18 | Modelling of mandiular movement 显示文摘 | Fang JJ Kuo TH | 2008 | Comput Biol Med2008，38，1112： | 1 |
| 19 | An observational study of ex- tracorporeal CPR for in-hospital cardiac arrest secondary to my- ocardial infarction 显示文摘 | Chou TH Fang CC Yen ZS | 2014 | Emerg Med J2014，31，6： | 1 |
| 20 | Diabetic eardiomyopathy: evidence,mechanisms,and therapeutic implications显示文摘 | Fang ZY Prins JB Marwick TH | 2004 | Endoc Rev2004，25，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员