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| 1 | Performance characterization of Ni60-WC coating on steel processed with supersonic laser deposition显示文摘Ni60-WC particles are used to improve the wear resistance of hard-facing steel due to their high hardness. An emerging technology that combines laser with cold spraying to deposit the hard-facing coatings is known as supersonic laser deposition. In this study, Ni60-WC is deposited on low-carbon steel using SLD. The microstructure and performance of the coatings are investigated through SEM, optical microscopy, EDS, XRD, microhardness and pin-on-disc wear tests. The experimental results of the coating processed with the optimal parameters are compared to those of the coating deposited using laser cladding. | Fang LUO Andrew COCKBURN Martin SPARKES Rocco LUPOI Zhi-jun CHEN William O'NEILL Jian-hua YAO Rong LIU | 2015 | Defence Technology(防务技术)2015，11，1： | 11 |
| 2 | Hardfacing steel with nanostructured coatings of Stellite-6 by supersonic laser deposition显示文摘The ability to manufacture coatings is critical to engineering design. Many components require the application of additional layers toenhance mechanical properties and protect against hostile environments. Supersonic laser deposition (SLD) is a novel coating methodbased on cold spray (CS) principles. In this technique, the deposition velocities can be significantly lower than those required foreffective bonding in CS applications. The addition of laser heat energy permits a change in the thermodynamic experience of impactingparticles, thereby offering a greater opportunity for efficient bonding at lower velocities as compared with the CS process. The workreported in this paper demonstrates the ability of the SLD process to deliver hardfacing materials to engineering surfaces. Stellite-6 hasbeen deposited on low-carbon steel tubes over a range of process parameters to establish the appropriate target power and traversespeeds for the coating formation. The coating properties and parameters were examined to determine the primary characteristics andgrain structure size. Their morphology and performance were studied through optical microscopy, scanning electron microscope(SEM), X-ray diffraction, hardness measurements and wear testing. The results have shown that SLD is capable of depositing layers ofStellite-6, with properties that are superior to those of their conventionally manufactured counterparts. | Rocco Lupoi Andrew Cockburn Chris Bryan Martin Sparkes Fang Luo William O’Neill | 2012 | Light(Science & Applications)2012，1，1： | 8 |
| 3 | Characteristics of Stellite 6 Deposited by Supersonic Laser Deposition Under Optimized Parameters显示文摘Stellite 6 powders were deposited on low carbon steel using SLD (supersonic laser deposition) under optimized parameters. The structure, line scan of elements and porosity of coating were examined and analyzed using SEM (scanning electron microscope), OM (optical microscope) and XRD (X-ray diffraction). The adhesion strength between coating and substrate was tested by PAT-ADHESION/TENSILE and E900STM adhesive. The results showed the deposition characteristics of optimized coating with N2 at a pressure of 3.0 MPa, a temperature of 450 ℃ and a laser power of 1.5 kW were compared with those of Stellite 6 coating deposited by the HVOF (high velocity oxygen fuel). | LUO Fang Lupoi Rocco Cockburn Andrew Sparkes Martin O'neill William YAO Jian-hua | 2013 | Journal of Iron and Steel Research(International)2013，20，2： | 4 |
| 4 | Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts显示文摘The accumulation and aggregation of alpha-synuclein(α-syn)in several tissue including the brain is a major pathological hallmark in Parkinson’s disease(PD).In this study,we show that α-syn can be taken up by primary human cortical neurons,astrocytes and skin-derived fibroblasts in vitro.Our findings that brain and peripheral cells exposed to α-syn can lead to impaired mitochondrial function,leading to cellular degeneration and cell death,provides additional evidence for the involvement of mitochondrial dysfunction as a mechanism of toxicity of α-syn in human cells. | Nady Braidy Wei-Ping Gai Ying Hua Xu Perminder Sachdev Gilles J Guillemin Xing-Mai Jiang J William O Ballard Martin P Horan Zhi Ming Fang Beng H Chong Daniel Kam Yin Chan | 2013 | Translational Neurodegeneration2013，2，1： | 4 |
| 5 | Eosinophilic Esophagitis in Adults is Associated with IgG4 and Not Mediated by IgE显示文摘 | Frederic Clayton John C. Fang Gerald J. Gleich Alfredo J. Lucendo Jose M. Olalla Laura A. Vinson Amy Lowichik Xinjian Chen Lyska Emerson Kristen Cox Molly A. O’Gorman Kathryn A. Peterson | 2014 | Gastroenterology2014，，： | 3 |
| 6 | Risk Factors for Posterior Compared to Anterior Ischemic Stroke: An Observational Study of the Registry of the Canadian Stroke Network显示文摘 | Subramanian G Silva J Silver F L Fang J Kapral M K Oczkowski W Gould L O’donnell M J | 2009 | Neuroepidemiology2009，，1： | 2 |
| 7 | Risk stratification in symptomatic intracranial atherosclerotic disease with conventional vascular risk factors and cerebral haemodynamics显示文摘Background and purpose Symptomatic intracranial atherosclerotic stenosis(sICAS)is associated with a considerable risk of recurrent stroke despite contemporarily optimal medical treatment.Severity of luminal stenosis in sICAS and its haemodynamic significance quantified with computational fluid dynamics(CFD)models were associated with the risk of stroke recurrence.We aimed to develop and compare stroke risk prediction nomograms in sICAS,based on vascular risk factors and these metrics.Methods Patients with 50%-99%sICAS confirmed in CT angiography(CTA)were enrolled.Conventional vascular risk factors were collected.Severity of luminal stenosis in sICAS was dichotomised as moderate(50%-69%)and severe(70%-99%).Translesional pressure ratio(PR)and wall shear stress ratio(WSSR)were quantified via CTA-based CFD modelling;the haemodynamic status of sICAS was classified as normal(normal PR&WSSR),intermediate(otherwise)and abnormal(abnormal PR&WSSR).All patients received guideline-recommended medical treatment.We developed and compared performance of nomograms composed of these variables and independent predictors identified in multivariate logistic regression,in predicting the primary outcome,recurrent ischaemic stroke in the same territory(SIT)within 1 year.Results Among 245 sICAS patients,20(8.2%)had SIT.The D2H2A nomogram,incorporating diabetes,dyslipidaemia,haemodynamic status of sICAS,hypertension and age≥50 years,showed good calibration(P for Hosmer-Lemeshow test=0.560)and discrimination(C-statistic 0.73,95%CI 0.60 to 0.85).It also had better performance in risk reclassification and provided larger net benefits in decision curve analysis,compared with nomograms composed of conventional vascular risk factors only,and plus the severity of luminal stenosis in sICAS.Sensitivity analysis in patients with anterior-circulation sICAS showed similar results.Conclusions The D2H2A nomogram,incorporating conventional vascular risk factors and the haemodynamic significance of sICAS as assessed in CFD models,could be a useful tool to stratify sICAS patients for the risk of recurrent stroke under contemporarily optimal medical treatment. | Xuan Tian Hui Fang Linfang Lan Hing Lung Ip Jill Abrigo Haipeng Liu Lina Zheng Florence S Y Fan Sze Ho Ma Bonaventure Ip Bo Song Yuming Xu Jingwei Li Bing Zhang Yun Xu Yannie O Y Soo Vincent Mok Ka Sing Wong Thomas W Leung Xinyi Leng | 2023 | Stroke & Vascular Neurology2023，8，1： | 2 |
| 8 | Arrayed CNx NT-RuO2 Nanocomposites Directly Grown on Ti-buffered Si Substrate for Supercapacitor Applications 显示文摘 | Fang W Chyan O Sun C | 2007 | Electrochem Commun2007，9，： | 1 |
| 9 | Face recognitionalgorithms surpass humans matchingfaces over changesinil-lu-mination显示文摘 | O’Toole AJ Phillips PJ Jiang Fang | 2007 | IEEE Transactions on Pattern Analysis andMachine Intelligence2007，29，8： | 1 |
| 10 | BRCAI is a selec- tive co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells 显示文摘 | Aprelikova O Pace A J Fang B | 2001 | J Biol Chem2001，276，25： | 1 |
| 11 | Electrochemical- thermal Modeling of Automotive Li Ion Batteries and Experimental Validation Using a Three-electrode Cell 显示文摘 | FANG W F KWON O J WANG C Y | 2010 | International Journal of Energy Research2010，34，2： | 1 |
| 12 | Rapid determination of the chloride diffusivity in concrete by applying an electrical fieht 显示文摘 | Fang L P Nilsson L O | 1992 | ACI Materials Journal1992，89，1： | 1 |
| 13 | An effective method for silver-staining DNA in large numbers of polyacrylamide gels 显示文摘 | Byun S O Fang Q Zhou H | 2009 | Analytical Biochemistry2009，385，1： | 1 |
| 14 | Binding Behavior of Calcium of Polyuronates: Comparison of Pectin with Alginate 显示文摘 | FANG Y AL-ASSAF S PHILLIPS G O | 2008 | Cabohydrate Polymers2008，72，： | 1 |
| 15 | Molecular cloning,character- rization and expression of goose Toll-like receptor 5 显示文摘 | FANG O PAN Z GENGS | 2012 | Mol Immuno12012，52，34： | 1 |
| 16 | Single-molecule atomic force microscopy on live cells compares aptamer and antibody rupture forces显示文摘 | O'donoghue M B Shi X Fang X | 2012 | Analytical and Bioanalytical Chemistry2012，402，10： | 1 |
| 17 | Arrayed CNx NT-RuO2 nanocomposites directly grown on Ti-buffered Si substrate for supercapacitor applications显示文摘 | FANG W C CHYAN O SUN C L | 2007 | Electrochemistry Communications2007，9，2： | 1 |
| 18 | A hybrid AlGaInAssilicon evanescent amplifier显示文摘 | PARK H FANG A W COHEN O | 2007 | IEEE Photonies Technology Letters2007，19，4： | 1 |
| 19 | Liquid phase sintering of functionally graded WC-Co composites 显示文摘 | FANG Z Z ESO 0 O | 2005 | Scripta Materialia2005，52，： | 1 |
| 20 | Overexpress ion of both VEGF-Aand VEGF-C in gastric cancercorrelates with prognosis, andsilencing of both is effectiveto inhibit cancer growth 显示文摘 | X i a o 1e i Wang X i m e i Chen Jianping Fang | | International journal ofclinical and experimentalpathology0，6，4： | 1 |
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