|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Two Dimension C_3N_4/MoS_2 Nanocomposites with Enhanced Photocatalytic Hydrogen Evolution under Visible Light Irradiation显示文摘MoS_2-decorated C_3N_4(C_3N_4/MoS_2) nanosheets hybrid photocatalysts were prepared by a simple sonication-impregnation method. Face-to-face lamellar heterojunctions were well established between two dimension(2D) C_3N_4 and MoS_2 nanosheets. The effects of MoS_2 content on the light absorption, charge transfer and photocatalytic activity of the hybrid samples were investigated. Characterization results show that MoS_2 nanosheets are well anchored on the face of C_3N_4 nanosheets and the composites have well dispersed layered morphology. After loading with MoS_2, the light absorption of composites was much improved, especially in visible-light region. The photocatalytic activities of C_3N_4/MoS_2 samples were evaluated based on the H_2 evolution under visible light irradiation(λ > 400 nm). When the loading amount of MoS_2 was increased to 5 wt%, the highest H_2 evolution rate(274 μmol·g^(-1)·h^(-1)) was obtained. Compared with samples obtained from direct impregnation method, sonication pretreatment is favorable for the formation of 2D layered heterojuctions and thus improve the photocatalytic activity. Slightly deactivation of C_3N_4/MoS_2 composites could be observed when recycled due to the mild photocorrosion of MoS_2. Based on the band alignments of C_3N_4 and MoS_2, a possible photocatalytic mechanism was discussed, where MoS_2 could efficiently promote the separation of the photogenerated carriers of C_3N_4. | 崔言娟 YANG Chuanfeng TANG Sheng ZHAO Yimeng CHEN Fangyan | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，1： | 2 |
| 2 | Simple hybrid dithiafulvenes-triphenylamine systems as dopant-free hole-transporting materials for efficient perovskite solar cells显示文摘Two extended hybrid conjugated systems based on a triphenylamine(TPA) core with two and three peripheral 1,4-dithiafulvenes(DTF) units coded WH-2 and WH-3 as hole-transporting materials(HTMs) applied in perovskite solar cells(PSCs) are synthesized by facile one-step reaction in good yield over 75%. DTF unit as electron donor can enhance the electron donating ability and the fusion of benzenic ring of TPA with DTF unit may lead to reinforced intermolecular interactions in the solid state. In addition,WH-2 and WH-3 exhibit a pyramid shape containing partial planarity and quasi three-dimensionality features, which is also conducive to enhancing the π-π stacking of molecules in the solid state. The above-mentioned structural characteristics make the two HTMs have good hole mobilities. As a result,WH-2 and WH-3 obtained the high intrinsic hole mobilities of 4.69 × 10^(-4)and 2.18 × 10^(-3)cm^(2)V^(-1)s^(-1)respectively. Finally, the power conversion efficiencies(PCEs) of PSCs with WH-2 and WH-3 as cost-effective dopant-free HTMs are 15.39% and 19.22% respectively and the PCE of PSC with WH-3 is on a par with that of PSC with Li-TFSI/t-BP doped Spiro-OMe TAD(19.67%). | Zhongquan Wan Yunpeng Zhang Jinyu Yang Jianxing Xia Fangyan Lin Xiaojun Yao Junsheng Luo Chunyang Jia | 2022 | Journal of Energy Chemistry2022，31，5： | 2 |
| 3 | A solid phase radioimmunoassay for free triiodothyronine in serum:assay development and validation显示文摘A solid phase radioimmunoassay for free triiodothyronine in serum was developed based on double-antibody coated tubes. The method was turned out to be reliable with good reproducibility, higher sensitivity and easy performance. The measurable range of FT3 in serum was 1.2 to 38 pmol/L. The mean coefficients of variation within and between assays were 1.79%-3.18% and 4.72%-9.31%, respectively. The FT3 concentrations in euthyroid serum as determined by this method were 2.8 to 7.8pmol/L. The FT3 values determined by this new method correlated well with those measured by a commercial radioimmunoassay (r=0.853). | LIU Fangyan ZHOU Meiying YIN Linxiang YANG Jianzhong HUA Chenglin (Shanghai Institute of Nuclear Research, the Chinese Academy of Sciences, Shanghai 201800 ) | 1999 | Nuclear Science and Techniques1999，10，1： | 1 |
| 4 | Multiple-scrolls chaotic attractor and circuit implementation显示文摘 | Qingdu Li Xiao-Song Yang Fangyan Yang | 2003 | Electron Lett2003，39，18： | 1 |
| 5 | A Rigorous Verification of Chaos in an Inertial Two-Neuron System 显示文摘 | YANG Xiaosong YANG Fangyan | 2004 | Chaos Solitons and Fractals2004，20，3： | 1 |
| 6 | A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism显示文摘Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity. | Lianju Qin Jing Zhang Yujie Xiao Kang Liu Yugui Cui Fangyan Xu Wenkai Ren Yanggang Yuan Chunyan Jiang Song Ning Xiaoxue Ye Ming Zeng Hanyang Qian Anning Bian Fan Li Guang Yang Shaowen Tang Zhihong Zhang Juncheng Dai Jing Guo Qiang Wang Bin Sun Yifei Ge Chun Ouyang Xueqiang Xu Jing Wang Yaoyu Huang Hongqing Cui Jing Zhou Meilian Wang Zhonglan Su Yan Lu Di Wu Jingping Shi Wei Liu Li Dong Yinbing Pan Baiqiao Zhao Ying Cui Xueyan Gao Zhanhui Gao Xiang Ma Aiqin Chen Jie Wang Meng Cao Qian Cui Li Chen Feng Chen Youjia Yu Qiang Ji Zhiwei Zhang Mufeng Gu Xiaojun Zhuang Xiaolin Lv Hui Wang Yanyan Pan Ling Wang Xianrong Xu Jing Zhao Xiuqin Wang Cuiping Liu Ningxia Liang Changying Xing Jiayin Liu Ningning Wang | 2022 | Journal of Molecular Cell Biology2022，14，2： | 1 |
| 7 | CD36 promotes tubular ferroptosis by regulating the ubiquitination of FSP1 in acute kidney injury显示文摘Reactive oxidative species(ROos)production-driven ferroptosis plays a role in acute kidney injury(Akl).However,its exact molecular mechanism is poorly understood.Scavenger receptor CD36 has important roles in oxidizing lipids,lipid accumulation,metabolic syndrome,and insulin resistance in chronic kidney disease,but its roles remain unexplored in AKl.The present study investigated the role and mechanism of CD36 in regulating proximal tubular cell ferroptosis and AKl.The expression of CD36 was found to be significantly up-regulated in AKI renal tissues and correlated with renal function,which might serve as an independent biomarker for AKl patients.Moreover,in adult mice subjected to AKl,deletion of CD36(CD36-/-)induced tubular cell Ros accumulation,ferroptosis activation,and renal injury.Mechanistically,combining LC-MS/MS,co-IP,and ubiquitination analyses revealed that CD36 could specifically bind to ferroptosis suppressor protein 1(FSP1)and regulate its ubiquitination at sites K16 and K24,leading to FSP1 degradation and progression of ferroptosis in AKl.The present results emphasize a novel mechanism of CD36 in cisplatin-induced AKl.The discovery of the special CD36 roles in promoting ferroptosis and AKI development by regulating the ubiquitination of FSP1 in proximal tubular cells may be potential therapeutic targets for AKl.Moreover,CD36 may play a key role in the progression of AKl.Therefore,targeting CD36 may provide a promising treatment option for AKI. | Yixin Ma Lili Huang Zheng Zhang Pengfei Yang Qingsong Chen Xujia Zeng Fangyan Tan Chunxia Wang Xiongzhong Ruan Xiaohui Liao | 2024 | Genes & Diseases2024，11，1： | 0 |
| 8 | The QseB/QseC two-component system contributes to virulence of Actinobacillus pleuropneumoniae by downregulating apf gene cluster transcription显示文摘Actinobacillus pleuropneumoniae(APP)is the major pathogen of porcine contagious pleuropneumoniae(PCP).The QseB/QseC two-component system(TCS)consists of the regulator QseB and the kinase QseC,which relates to quorum sensing(QS)and virulence in some bacteria.Here,we investigated the role of QseB/QseC in apf gene cluster(apfABCD)expression of APP.Our results have showed that QseB/QseC TCS can potentially regulate the expression of apf gene cluster.The△qseBC,△apfA,△apfB,△apfC and△apfD strains are more sensitive to acidic and osmotic stressful conditions,and exhibite lower biofilm formation ability than wild-type(WT)strain,whereas the complemented strains show similar phenotype to the wr strain.In additon,the mutants have defective antiphagocytosis,adhesion and invasion when they come into contact with the host cells.In experimental animal models of infection,mice infected with△qseBC,△apfA,△apfB,△apfC and △apfD strains showed lower mortality and bacterial loads in the lung and the blood than those infected with wr strain.In conclusion,our results suggest that QseB/QseC TCS contributes to stress resistance,biofilm formation,phagocytosis,adhesion,invasion and virulence by downregulating expression of apf gene cluster in A.pleuropneumoniae. | Benzhen Duan Wei Peng Kang Yan Feng Liu Jia Tang Feng ming Yang Huanchun Chen Fangyan Yuan Weicheng Bei | 2022 | Animal Diseases2022，2，1： | 0 |
| 9 | A bHLH transcription factor,CsSPT,regulates high-temperature resistance in cucumber显示文摘High-temperature stress threatens the growth and yield of crops. Basic helix-loop-helix(bHLH) transcription factors(TFs) have been shown to play important roles in regulating high-temperature resistance in plants. However, the bHLH TFs responsible for high-temperature tolerance in cucumbers have not been identified. We used transcriptome profiling to screen the high temperature-responsive candidate bHLH TFs in cucumber. Here, we found that the expression of 75 CsbHLH genes was altered under high-temperature stress. The expression of the CsSPT gene was induced by high temperatures in TT(Thermotolerant) cucumber plants. However, the Csspt mutant plants obtained by the CRISPR-Cas9 system showed severe thermosensitive symptoms, including wilted leaves with brown margins and reduced root density and cell activity.The Csspt mutant plants also exhibited elevated H_(2)O_(2) levels and down-regulated photosystem-related genes under normal conditions.Furthermore, there were high relative electrolytic leakage(REC), malondialdehyde(MDA), glutathione(GSH), and superoxide radical(O_(2)^(·-)) levels in the Csspt mutant plants, with decreased Proline content after the high-temperature treatment. Transcriptome analysis showed that the photosystem and chloroplast activities in Csspt mutant plants were extremely disrupted by the high-temperature stress compared with wildtype(WT) plants. Moreover, the plant hormone signal transduction, as well as MAPK and calcium signaling pathways were activated in Csspt mutant plants under high-temperature stress. The HSF and HSP family genes shared the same upregulated expression patterns in Csspt and WT plants under high-temperature conditions. However, most bHLH, NAC, and bZIP family genes were significantly down-regulated by heat in Csspt mutant plants. Thus, these results demonstrated that CsSPT regulated the high-temperature response by recruiting photosynthesis components, signaling pathway molecules, and transcription factors. Our results provide important insights into the heat response mechanism of CsSPT in cucumber and its potential as a target for breeding heat-resistant crops. | Yonggui Liang Chenyu Yang Fangyan Ming Bingwei Yu Zhihua Cheng Yixi Wang Zhengkun Qiu Xiaolan Zhang Bihao Cao Shuangshuang Yan | 2024 | Horticultural Plant Journal2024，10，2： | 0 |
| 10 | First Isolation and Identification of Shewanella xiamenensis from Diseased Nile Tilapia(Oreochromis niloticus L.)显示文摘A gram-negative,motile,and rod-shaped bacterium,strain JF02,was isolated from the liver of diseased GIFT( genetically improved farmed tilapia) in Hainan,China. The strain JF02 was lethal to GIFT,and most GIFT infected with JF02 exhibited the same clinical signs,such as black body,pale or focally necrosis of the gills,scale shedding,fin rot,liver hyperemia,and hydroabdomen. The 16 S rRNA gene sequences of strain JF02 showed 99. 7% similarity with that of Shewanella xiamenensis strain S4~T. In addition,the gyr B gene sequences of strain JF02 showed 99. 0% similarity with that of S. xiamenensis strain S4~T. Combining the results of morphological,physiological and biochemical characteristics,the isolated strain JF02 was confirmed to be S. xiamenensis. The chemotherapeutic antibiotics tests showed that the strain JF02 was sensitive to most antibiotics except for several common antibiotics that were frequently used in human medicines and treatment of bacterial diseases of fish,indicating that the strain JF02 has obtained many antibiotic resistance genes due to the long-term abuse of antibiotics in aquaculture. In this paper,it was the first time to report that the S. xiamenensis may be a potential pathogen for GIFT. It is time to promote awareness of the potential harm of this strain to the health of human and aquatic animals. | Jun MA Ning YANG Yan CHEN Fangyan JIANG Hai HUANG | 2018 | Agricultural Biotechnology2018，7，1： | 0 |
| 11 | Clonal variation in growth,PSII photochemical activity and polar metabolites in Pinus elliottii×P.caribaea显示文摘Pinus elliottii×P.caribaea is a widely planted commercial tree hybrid in South China.To investigate the potential of physiological parameters for clonal selection,cuttings of three clones(EH3,EH4 and EH5)and a control were grown in phosphorus treated pots.Significant variations to phosphorous,photosystem II activity and polar metabolite abundance in needles were noted among clones.Clone EH5 was the most P-responsive and had maximum height growth.The highest maximum quantum yield of PSII in the dark(F_(v)/F_(m)),maximum quantum yield of PSII in the light(F_(v)'/F_(m)')and the actual PSII efficiency(Φ_(PSII))values were also found in EH5.A total of 64 polar metabolites were identified,21 were regulated by phosphorous,while 28 accumulated differentially among the three clones.There were few overlapping responsive metabolites to phosphorous fertilization.In EH5,the abundance of maltotriitol,neohesperidin and raffinose were highest,whereas galactinol and shikimic acid were lower compared with EH3 and EH4.The results reveal that physiological traits were genetically controlled and might be useful for selecting clones with high phosphorous utilization efficiency. | Wenbing Guo Fencheng Zhao Yang Liu Zhen Li Huishan Wu Yiliang Li Fangyan Liao | 2022 | Journal of Forestry Research2022，33，1： | 0 |
| 12 | Chelation of lithium ion with crown ether for eliminating adverse effects caused by Li-TFSI/tBP doping system in Spiro-OMeTAD显示文摘Lithium bis(trifluoromethanesulfonyl)imide(Li-TFSI)/4-tert-butylpyridine(tBP)is a classic doping system for the hole transport material Spiro-OMeTAD in typical n-i-p structure perovskite solar cells(PSCs),but this system will cause many problems such as high hygroscopicity,Li+migration,pinholes and so on,which hinder PSC from maintaining high efficiency and stability for long-term.In this work,an effective strategy is demonstrated to improve the performance and stability of PSC by replacing t BP with 12-crown-4.The chelation of 12-crown-4 with Li+not only improves the doping effect of Li-TFSI,but also perfectly solves the problems caused by the Li-TFSI/tBP system.The PSC based on this strategy achieved a champion power conversion efficiency(PCE)over 21%,which is significantly better than the pristine device(19.37%).More importantly,the without encapsulated device based on Li-TFSI/12-crown-4 still maintains 87%of the initial PCE even after 60 days exposure in air,while the pristine device only maintains 22%of the initial PCE under the same aging conditions.This strategy paves a novel way for constructing efficient and stable PSCs. | Zhongquan Wan Hui Lu Jinyu Yang Yunpeng Zhang Fangyan Lin Jianxing Xia Xiaojun Yao Junsheng Luo Chunyang Jia | 2022 | Journal of Energy Chemistry2022，31，11： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员