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| 1 | Effects of percutaneous varicocele repair on testicular volume:results from a 12-month follow-up显示文摘Varicocele is a comm on fin ding in men. Varicocele correcti on has bee n advocated for young patients with testicular hypotrophy, but there is a lack of morphofunctional follow-up data. We assessed whether percutaneous treatment of left varicocele is associated with testicular 'catch-up growth' in the following 12 months by retrospectively reviewing data from an electronic database of 10 656 patients followed up in our clinic between 2006 and 2016. We selected all young adults (<35 years) with left varicocele who un derwe nt percuta neous treatment, had a minimum of 12 mon ths' ultraso und imagi ng follow-up, and had no other con ditions affecting testicular volume. One hundred and fourteen men (mean±standard deviation [s.d.] of age: 22.8 ± 5.4 years) met the inclusion and exclusion criteria. Left testicular hypotrophy (LTH), defined as a >20% difference between left and right testicular volume at baseline, was observed in 26 (22.8%) men. Participants with LTH (mean±s.d.: 14.5 ± 2.7 ml) had lower baseline testicular volume compared to those without LTH (mean±s.d.: 15.7 ± 3.8 ml;P= 0.032). Repeated measures mixed models showed a sign ifica nt in teraction betwee n LTH and time posttreatme nt when correcting for baseli ne left testicular volume (β= 0.114, 95% confidence interval [Cl]: 0.018-0.210, P=0.020), resulting in a catch-up growth of up to 1.37 ml per year (95% Cl: 0.221- 2.516). Age at intervention was also associated with reduced testicular volume (-0.072 ml per year, 95% Cl:-0.135--0.009;P = 0.024). Percutaneous treatment of left varicocele in young adults with LTH can result in catch-up growth over 1 year of follow-up. The reproductive and psychological implicati ons of these findings n eed to be confirmed in Ion ger and larger prospective studies. | Andrea Sansone Danilo Alunni Fegatelli Carlotta Pozza Giorgio Fattorini Rosa Lauretta Marianna Minnetti Francesco Romanelli Pierleone Lucatelli Mario Corona Mario Bezzi Francesco Lombardo Andrea Lenzi Daniele Gianfrilli | 2019 | Asian Journal of Andrology2019，21，4： | 8 |
| 2 | ABCB1 and ABCB19 auxin transporters have synergistic effects on early and late Arabidopsis anther development显示文摘Arabidopsis abcb1 abcb19 double mutants defective in the auxin transporters ABCB1/PGP1 and ABCB19/PGP19 are altered in stamen elongation, anther dehiscence and pollen maturation. To assess the contribution of these transporters to stamen development we performed phenotypic, histological analyses, and in situ hybridizations on abcb1 and abcb19 single mutant fl owers. We found that pollen maturation and anther dehiscence are precocious in the abcb1 but not in the abcb19 mutant. Accordingly, endothecium ligni fication is altered only in abcb1 anthers. Both abcb1 and abcb1 abcb19 stamens also show altered early development, with asynchronous anther locules and a multilayer tapetum. DAPI staining showed that the timing of meiosis is asynchronous in abcb1 abcb19 anther locules, while only a small percentage of pollen grains are nonviable according to Alexander's staining. In agreement, TAM(TARDY ASYNCHRONOUS MEIOSIS), as well as BAM2(BARELY ANY MERISTEM)—involved in tapetal cell development—are overexpressed in abcb1 abcb19 young fl ower buds. Corre spondingly, ABCB1 and ABCB19 mRNA localization supports the observed phenotypes of abcb1 and abcb1 abcb19 mutant anthers. In conclusion, we provide evidence that auxin transport plays a signi ficant role both in early and late stamen development: ABCB1 plays a major role during anther development, while ABCB19 has a synergistic role. | Valentina Cecchetti Patrizia Brunetti Nadia Napoli Laura Fattorini Maria Maddalena Altamura Paolo Costantino Maura Cardarelli | 2015 | Journal of Integrative Plant Biology2015，57，12： | 2 |
| 3 | Nonlinear surface EMG analysis to detect changes of motor unit conduction velocity and synchronization显示文摘 | FARINA D FATTORINI L FELICI F | 2002 | J Appl Physiol2002，93，： | 1 |
| 4 | Levobupivacaine versus race- micbupivacaine for spinal Anaesthesia in orthopaedic major surgery 显示文摘 | Fattorini F Ricei Z Rocco A | 2006 | Minerva Anesth2006，72，7： | 1 |
| 5 | Antioxidant efficiency in early life stages of the antarctic silverfish,Pleuragramma antarcticum:responsiveness to pro-oxidant conditions of platelet ice and chemical exposure显示文摘 | Nigro F M Benedetti M Fattorini | | 0，，： | 1 |
| 6 | Seasonal,spatial and inter-annual variations of trace metals in mussels from the Adriatic sea:a regional gradient for arsenic and implications for monitoring the impact of off-shore activities显示文摘 | FATTORINI D NOTTI A DI MENTO R | | 0，，10： | 1 |
| 7 | Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug-resistant Mycobacterium tuberculosis infection in BALB/c mice显示文摘 | Fattorini L Tan D Iona E | | 0，，： | 1 |
| 8 | Nonlinear surface EMG analysis to detect changes of motor unit conduction velocity and synchronization显示文摘 | Farina D Fattorini L Felici F | 2002 | J Appl Physiol2002，93，： | 1 |
| 9 | Resistance to beta-lactams in Mycobacterium fortuitum 显示文摘 | Fattorini L Orefici G Jin S H | 1992 | Antimicrob Agents Chemother1992，36，5： | 1 |
| 10 | Loss of heterozygosity and K-ras gene mutations in gastric cancer显示文摘 | G. N. Ranzani B. Renault N. S. Pellegata P. Fattorini E. Magni F. Bacci D. Amadori | 1993 | Human Genetics1993，，3： | 1 |
| 11 | Necessarsy and sufficient conditions for optimal controls in viscous flow problems显示文摘 | FATTORINI H O SRITHARAN S S | 1994 | Proceedings of the Royal Society of Edinburgh1994，124，2： | 1 |
| 12 | Existence of optimal control for viscous flow problems显示文摘 | FATTORINI H O SRITHARAN S S | 1992 | Proceedings: Mathematical and Physical Sciences1992，439，： | 1 |
| 13 | Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug - resis- tant Mycobacterium tuberculosis infectionin BALB/c mice显示文摘 | Fattorini L Tan D Iona E | 2003 | Antimi- crob Agents Chemothera2003，47，1： | 1 |
| 14 | Thrombotic microangiopathy in pregnancy显示文摘 | Angelo A D Fattorini A Crippa L | 2009 | Thromb Res2009，123，7： | 1 |
| 15 | To fit or not to fit? A poorly fitting proce dure produces inconsistent results when the species-are a relationship is used to locate hotspots显示文摘 | Fattorini S | 2007 | Biodiversi ty and Consernation2007，16，9： | 1 |
| 16 | Extensively drug-resistant (XDR) tuberculosis an old and new threat显示文摘 | Fattorini L Migliori GB Cassone A | 2007 | Ann Ist Super Sanita2007，43，4： | 1 |
| 17 | Strategies for the development of new tuberculosis vaccines显示文摘 | Fattorini L | 2007 | Minerva Med2007，98，2： | 1 |
| 18 | Seed rain in high altituderestoration plots in Switzerland显示文摘 | Urbanska K W Fattorini M | 2000 | Restoration Ecol-ogy’2000，8，： | 1 |
| 19 | Biceps brachii myoelectric and oxygenation changes during static and sinu- soidal isometric exercises显示文摘 | Felici F Quaresima V Fattorini L | 2009 | J Electromyogr Kinesiol2009，19，2： | 1 |
| 20 | Motor performance changes induced by muscle vibration显示文摘 | Luigi Fattorini Aldo Ferraresi Angelo Rodio Gian Battista Azzena Guido Maria Filippi | 2006 | European Journal of Applied Physiology2006，，1： | 1 |
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