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| 1 | Combined genome-wide association study and transcriptome analysis reveal candidate genes for resistance to Fusarium ear rot in maize显示文摘Fusarium ear rot,caused by Fusarium verti-cillioides,is a devastating fungal disease in maize that re-duces yield and quality;moreover,F.verticillioides pro-duces fumonisin mycotoxins,which pose serious threats to human and animal health.Here,we performed a genome-wide association study(GWAS)under three en-vironmental conditions and identified 34 single-nucleotide polymorphisms(SNPs)that were significantly associated with Fusarium ear rot resistance.With reference to the maize B73 genome,69 genes that overlapped with or were adjacent to the significant SNPs were identified as potential resistance genes to Fusarium ear rot.Comparing transcriptomes of the most resistant and most susceptible lines during the very early response to Fusarium ear rot,we detected many differentially expressed genes enriched for pathways related to plant immune responses,such as plant hormone signal transduction,phenylpropanoid bio-synthesis,and cytochrome P450 metabolism.More than one-fourth of the potential resistance genes detected in the GWAS were differentially expressed in the tran-scriptome analysis,which allowed us to predict numbers of candidate genes for maize resistance to ear rot,in-cluding genes related to plant hormones,a MAP kinase,a PR5-like receptor kinase,and heat shock proteins.We propose that maize plants initiate early immune responses to Fusarium ear rot mainly by regulating the growth-defense balance and promoting biosynthesis of defense compounds. | Lishan Yao Yanmei Li Chuanyu Ma Lixiu Tong Feili Du Mingliang Xu | 2020 | Journal of Integrative Plant Biology2020，62，10： | 13 |
| 2 | First-principle calculation of distorted T-carbon as a promising anode for Li-ion batteries with enhanced capacity, reversibility, and ion migration properties显示文摘Carbon group element-based materials are the most widely used anode materials for Li-ion batteries(LIBs).However,their performance is limited by the low capacity(eg,graphite)or high-volume changes(eg,Si and Sn).Therefore,exploring high-performance anode materials is quite appealing and promising.By first-principle calculations in this study,we found that distorted T-carbon(DTC)as a desired LIB anode shows properties of the enhanced capacity,decreased volume change,and the increased ion migration.The origin of such improved properties is attributed to the interconnected tunnels and large cavities of the carbon skeleton.The theoretical specific capacity of DTC is found to be 558 mAh/g,which is 1.5 times higher than that of commercial graphite anodes.Interestingly,the volume change of the DTC anode is only 3%at the full-lithiation state(one-fifth of that of the commercial graphite anode),which can overcome the pulverization problem in most high-capacity anode materials and attain a longer cycling lifetime.Both transition state calculations and molecular dynamics simulations demonstrate that the Li-ion migration barrier is less than 0.1 eV and the Li-ion vacancy is only 0.2 eV,enabling its promising rate performance.This study provides a new and effective strategy to improve the anode properties of LIBs. | Jianrui Feng Chao Yang Lijie Zhang Feili Lai Lei Du Xiaohua Yang | 2020 | Carbon Energy2020，2，4： | 0 |
| 3 | Preferential depletion of CD2^(low) plasmacytoid dendritic cells in HIV-infected subjects显示文摘Plasmacytoid dendritic cells(pDCs)are decreased in number and are functionally impaired in HIV act reasons for pDCs depletion are still unknown.It was recently reported that pDCs can be divided into two functionally distinct populations based on their CD2 expression level.To determine how the CD2high and CD2^(low) populations are affected by HIV infection,we analyzed their frequencies in the peripheral blood of HIV-infected subjects and healthy controls.We found that the CD2^(low) pDC subset was preferentially depleted in infected individuals.The frequency of CD2^(low) pDCs correlated with the CD41 T-cell count but not with the plasma viral load.This finding furthers our understanding of the causes and consequences of pDC depletion during HIV infection. | Qiumei Du Yanmei Jiao Wei Hua Rui Wang Feili Wei Yunxia Ji Peishuang Du Yong-Jun Liu Hao Wu Liguo Zhang | 2011 | Cellular & Molecular Immunology2011，8，5： | 0 |
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