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| 1 | Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study显示文摘AIM To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwan Residents military male cohort.METHODS We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study. Cases of chronic hepatitis B(n = 121) were defined by personal history and positive detection of hepatitis B surface antigen. Cases of nonalcoholic steatohepatitis(n = 129) were defined by alanine transaminase level > 60 U/L, liver ultrasound finding of steatosis, and absence of viral hepatitis A, B or C infection. All other study participants were defined as unaffected(n = 3419). Physical fitness was evaluated by performance in 3000-m run, 2-min sit-ups, and 2-min push-ups exercises, with all the procedures standardized by a computerized scoring system. Multiple linear regression analysis was used to determine the relationship.RESULTS Chronic hepatitis B negatively correlated with 2-min push-up numbers(β =-2.49, P = 0.019) after adjusting for age, service specialty, body mass index, systolic and diastolic blood pressures, current cigarette smoking, alcohol intake status, serum hemoglobin, and average weekly exercise times. Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time(β = 11.96, P = 0.084) and negatively correlated with 2-min sit-up numbers(β =-1.47, P = 0.040). CONCLUSION Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males, and future study should determine the underlying mechanism. | Yu-Jung Chen Kai-Wen Chen Yu-Leung Shih Fang-Ying Su Yen-Po Lin Fan-Chun Meng Felicia Lin Yun-Shun Yu Chih-Lu Han Chih-Hung Wang Jia-Wei Lin Tsai-Yuan Hsieh Yi-Hwei Li Gen-Min Lin | 2017 | World Journal of Gastroenterology2017，23，25： | 2 |
| 2 | The Gβy-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation显示文摘 | Lisheng Li Wanze Chen Yaoji Liang Huabin Ma Wenjuan Li Zhenru Zhou Jie Li Yan Ding Junming Ren Juan Lin Felicia Han Jianfeng Wu Jiahuai Han | 2014 | Cell Research2014，24，4： | 2 |
| 3 | A Processual Analysis of Knowledge Transfer from Foreign MNEs to Chinese Suppliers 显示文摘 | Jing- Lin Duanmua Felicia M Fai | 2007 | International Business Review2007，16，4： | 1 |
| 4 | A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development显示文摘 | Juan Lin Hanjie Li Min Yang Junming Ren Zhe Huang Felicia Han Jian Huang Jianhui Ma Duanwu Zhang Zhirong Zhang Jianfeng Wu Deli Huang Muzhen Qiao Guanghui Jin Qiao Wu Yinghui Huang Jie Du Jiahuai Han | 2013 | Cell Reports2013，，1： | 1 |
| 5 | A processual analysis of knowledge transfer: from foreign MNEs to Chinese suppliers 显示文摘 | Jing - Lin Duanmua Felicia M F | 2007 | International Business Review2007，，16： | 1 |
| 6 | Current Problems in Surgery: Gastric Cancer显示文摘 | Clancy J. Clark Richard C. Thirlby Vicent Picozzi Drew B. Schembre Felicia P. Cummings Eugene Lin | 2006 | Current Problems in Surgery2006，，： | 1 |
| 7 | Tsunami hazard from the subduction megathrust of the South China Sea: Part I. Source characterization and the resulting tsunami显示文摘 | Kusnowidjaja Megawati Felicia Shaw Kerry Sieh Zhenhua Huang Tso-Ren Wu Yunung Lin Soon Keat Tan Tso-Chien Pan | 2008 | Journal of Asian Earth Sciences2008，，1： | 1 |
| 8 | Rationale and design of the cardiorespiratory fitness and hospitalization events in armed forces study in Eastern Taiwan显示文摘AIM To investigate the association between cardiorespiratory fitness and hospitalization events in a cohort of large voluntary arm forces in Taiwan. METHODS The cardiorespiratory fitness and hospitalization events in armed forces(CHIEF) is a retrospective cohort consisting of more than 4000 professional military members aged 18-50 years in Eastern Taiwan. All participants received history taking, physical examination, chest radiography, 12-lead electrocardiography, blood tests for cell counts and fasting glucose, lipid profiles, uric acid, renal function and liver function in the Hualien Armed Forces General Hospital during 2014. In addition, participants were required to undergo two indoor resistant exercise tests including 2-min push-up and 2-min sit-up, both scored by infrared sensing, and one outdoor endurance 3000-m none weight-bearing running test, the main indicator of cardiorespiratory fitness in the Military Physical Training and Testing Center in Eastern Taiwan in 2014. RESULTS Hospitalization events for cardiovascular disease, acute kidney injury, rhabdomyolysis, severe infectious disease, acute psychiatric illness, diabetes, orthopedic surgery and mortality will be identified in the National Insurance Research Database for 10 years. CONCLUSION CHIEF will be among the largest Eastern Asian armed forces cohort, in which physical status was strictly evaluated to follow up the hospitalization events for severe illness. | Gen-Min Lin Yi-Hwei Li Chung-Jen Lee Jeng-Chuan Shiang Ko-Huan Lin Kai-Wen Chen Yu-Jung Chen Ching-Fen Wu Been-Sheng Lin Yun-Shun Yu Felicia Lin Fung-Ying Su Chih-Hung Wang | 2016 | World Journal of Cardiology2016，8，8： | 0 |
| 9 | Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD~ homeostasis and contributes to longevity显示文摘滋养的察觉到小径和他们的规定响应改变营养素在他们的新陈代谢和生长上同意房间控制。调整滋养的察觉到的因素能也调制长寿。察觉到象察觉到葡萄糖的 PKA,察觉到氮的岩山和 S6 kinase 相当或相同的事物 Sch9 那样的小径的营养素的减少的活动在酵母, Saccharomyces cerevisiae,和更高的优核质被连接了到增加的寿命。最近,减少了氨基酸察觉到 SPS 小径也被显示增加酵母寿命的活动。由减少的 SPS 活动的寿命扩展要求提高的 NAD +( 菸碱腺嘌 dinucleotide,氧化形式) 并且菸碱核糖甙(NR,一位 NAD + 先锋) 动态平衡。维持足够的 NAD + 水池被显示了在寿命扩展,而是因素调整 NAD + 新陈代谢和动态平衡起关键作用完全没被理解。最近, NAD + 新陈代谢也被连接到在酵母察觉到 PHO 小径的磷酸盐(Pi ) 。正规 PHO 激活要求 Pi 饥饿。有趣地,没有 Pi 饥饿的 NAD + 弄空是足够的导致 PHO 激活,增加 NR 生产和动员。而且,发信号的 SPS 看起来与表明部件调整 NR/NAD + 动态平衡的 PHO 同时工作。这些研究建议那 NAD + 新陈代谢多半被控制由或与多重滋养的察觉到小径协调了。确实, PHO, PKA,岩山和 Sch9 跨规定小径被报导潜在地影响 NAD + 新陈代谢;不过详细的机制仍然保持不清楚。这评论讨论酵母长寿相关滋养的察觉到小径和寿命扩展, NAD + 动态平衡的规定,和在滋养的察觉到之中的串音的可能的机制小径和 NAD + 动态平衡。 | Felicia Tsang Su-Ju Lin | 2015 | Frontiers in Biology2015，10，4： | 0 |
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