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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Oxygen sensitivity of cloned voltage-gated K + channels expressed in the pulmonary vasculature 显示文摘 | Hulme J T Coppock E A Felipe A | 1999 | Circulation Research1999，85，： | 1 |
| 3 | Cavitary pulmonary metastases in transitional cell carcinoma of urinary bladder 显示文摘 | Rovirosa A Salud A Felip E | 1992 | Urol Int1992，48，1： | 1 |
| 4 | Cavitary pulmonary metastases in transitional cell carcinoma of the urinary bladder 显示文摘 | Rovirosa A Salud A Felip E | 1992 | Urotlnt1992，48，1： | 1 |
| 5 | Effect of the oxygen transfer coefficient on xylitol production from sugarcane bagasse hydrolysate by continuous stirred-tank reactor fermentation 显示文摘 | MARTINEZ E A SILVA S S FELIPE M G A | 2000 | Applied Biochemistry and Biotechnology2000，8486，： | 1 |
| 6 | Batch xylitol production from wheat straw hemicellulosic hydrolysate using Candida guilliermondii in a stirred tank reactor显示文摘 | Larissa Canilha Joo B Almeida e Silva Maria G A Felipe | 2003 | Biotechnology Letters2003，25，： | 1 |
| 7 | Cavitary pulmonary metastases in transitional cell carcinoma of the urinary bladder 显示文摘 | Rovirosa A Salud A Felip E | 1992 | Urol Int1992，48，1： | 1 |
| 8 | Lung cancer survival in Germany : A population -based analysis of 132,612 lung Cancer patients 显示文摘 | Andrea E Lina J Felipe A | 2015 | Lung Cancer2015，90，3： | 1 |
| 9 | Symptom and quality of life results of an international randomised phase llI study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer 显示文摘 | Bottomley A Debruyne C Felip E | 2008 | Eur J Cancer2008，44，15： | 1 |
| 10 | Soil amendments reduce trace element solubility in a eontarninated soil and allow regrowth of natural vegetation显示文摘 | Madejon E Mora A P Felipe E | 2006 | Environ Poll2006，139，： | 1 |
| 11 | Oxygen sensitivity of cloned voltage-gated K + channels expressed in the pulmonary vasculature显示文摘 | Hulme J T Coppock E A Felipe A | 1999 | Circulation Research1999，85，： | 1 |
| 12 | Cavitary pulmonary metastases in transitional cell carcinoma of the urinary bladder显示文摘 | Rovirosa A Salud A Felip E | 1992 | Urol Int1992，48，1： | 1 |
| 13 | A hOVe; anti-apoptosis gene: Reexprossion of survivin messenger RNA as a prognosis marker in non-small cell lung cancer显示文摘 | Monzo M Roseu R Felip E et a/ | 1999 | J Clin Onvol1999，17，7： | 1 |
| 14 | E unum pluribus:multiple proteins from a self-processing polyprotein显示文摘 | de Felipe P Luke G A Hughes L E | | 0，，02： | 1 |
| 15 | Cavitary pulmonary metastases in transitional cell carcinoma of urinary bladder显示文摘 | Rovirosa A Salud A Felip E | 1992 | Urol Int1992，48，1： | 1 |
| 16 | Symptom and quality of life results of an international randomised phase Ⅲ study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer显示文摘 | Boomley A Debruyne C Felip E | 2008 | Eur J Cancer2008，44，15： | 1 |
| 17 | A takagi-sugeno model with fuzzy inputs viewed from multidimensional interval analysis显示文摘 | Felipe F A Julio G E | 2003 | Fuzzy Sets and Systems2003，135，1： | 1 |
| 18 | The influence of pH,temperature and hydrolysate concentration on the removal of volatile and non-volatile compounds from sugarcane bagasse hemicellulosic hydrolysate treated with activated charcoal before or after vacuum evaporation显示文摘 | Rodrigues R C L B Felipe M G A Almeida E | 2001 | Braz J Chem Eng2001，18，： | 1 |
| 19 | Poor-prognosis colon canceris defined by a molecularly distinct subtype and devel-ops from serrated precursor lesions显示文摘 | Felipe De Sousa E M Wang X Jansen M Fessler E Trinh A de Rooij LP | 2013 | Nat Med2013，19，： | 1 |
| 20 | Jasmonate modulates development and light-regulated alkaloid biosynthesis in Catharanthus Roseus显示文摘 | FLOTAAND V FELIPE A D E L V | 1998 | Phytochemistry1998，49，2： | 1 |
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