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| 1 | 肠道菌群促进血管紧张素Ⅱ诱导的高血压和血管功能障碍显示文摘肠道微生物对宿主生理反应及对免疫功能的发展来说必不可少。肠道菌群对血压和全身血管功能等这些由免疫细胞功能决定的生理过程的影响知之甚少。方法:与常规饲养的小鼠(conventionally raised rats,CONV-R)比较,未受任何细菌影响的无菌小鼠(GF)表现出较为严重的全身性辅助性T细胞1型滞后。 | 刘莉 叶鹏 Karbach SH Schnfelder T Brandao I Wilms E Hrmann N Jckel S Schüler R Finger S Knorr M Lagrange J Brandt M Waisman A Kossmann S Schüfer K Münzel T Reinhardt C Wenzel P | 2016 | 中华高血压杂志2016，24，10： | 5 |
| 2 | Psychiatric side effects of pegylated interferon alfa-2b as compared to conventional interferon alfa-2b in patients with chronic hepatitis C显示文摘AIM: To assess systematically the spectrum and extent of depressive symptoms comparing patient groups receiving peginterferon or conventional interferon.METHODS: Ninety-eight patients with chronic hepatitis C and interferon-based therapy (+ribavirin) were consecutively enrolled in a longitudinal study. Patients were treated with conventional interferon alfa-2b (48/98patients; 5 MIU interferon alfa-2b thrice weekly) or peginterferon alfa-2b (50/98 patients; 80-150 μgpeginterferon alfa-2b) in combination with weight-adapted ribavirin (800-1 200 mg/d). Repeated psychometric testing was performed before, three times during and once after antiviral therapy: Depression was evaluated by the Hospital Anxiety and Depression Scale (HADS), anger/hostility by the Symptom Checklist-90 Items Revised (SCL-90-R).RESULTS: Therapy with pegylated interferon alfa-2bproduces comparable scores for depression (ANOVA:P = 0.875) as compared to conventional interferon.Maximums of depression scores were even higher and cases of clinically relevant depression were frequent during therapy with peginterferon. Scores for anger/hostility were comparable for both therapy subgroups.CONCLUSION: Our findings suggest that the extent and frequency of depressive symptoms in total are not reduced by peginterferon. Monitoring and management of neuropsychiatric toxicity especially depression have to be considered as much as in antiviral therapy with unmodified interferon. | Michael R Kraus Arne Sch(a|¨)fer Herbert Csef Michael Scheurlen | 2005 | World Journal of Gastroenterology2005，11，12： | 5 |
| 3 | 型煤用粘结剂的种类和成分显示文摘0 前言粘结剂指的是可把粉煤粘结起来制成型煤的物质。凡是与煤亲合且能在冷却和硬化后形成坚实固体的物质,均可作为型煤粘结剂。型煤粘结剂的历史可上(?)到16世纪中叶,但直到1832年由E.Marsais申请的专利才带来了技术上的突破。他采用煤焦油沥青作为粘结剂,明显地提高了型煤强度。直到1976年,煤焦油沥青一直是最主要的型煤粘结剂。但是,在1974年颁布了严格的环保条例,限制了煤焦油沥青的广泛应用。因此人们转而采用石油沥青或木质素磺酸盐水溶液作为代用粘结剂。人们也曾对聚氨酯等塑性物料作了不少实验。 | H.G.Sch(a|¨)fer 林文元 | 1989 | 煤炭综合利用译丛1989，，3： | 2 |
| 4 | Use of the heartrail Ⅱ catheter as a distal stent delivery device: an extended case series显示文摘 | Mamas A Eichh? fer J Hendry C | 2009 | Eurointervention2009，5，2： | 1 |
| 5 | Laparoscopic versus open splenectomy for nontraumatic diseases显示文摘 | Maurus CF Sch(a)fer M Müller MK | | 0，，： | 1 |
| 6 | PRG1:a novel early-response gene transcriptionally induced by pituitary adenylate cyclase activating polypeptide in a pancreatic carcinoma cell line显示文摘 | Sch(a)fer H Trauzold A Siegel EG | 1996 | Cancer Res1996，56，11： | 1 |
| 7 | Cloning,sequencing,and characterization of a heat-and alkali-stable type Ⅰ pullulanase from Anaerobranca gottschalkii显示文摘 | Bertoldo C Armbrecht M Becker F Sch(a)fer T Antranikian G Liebl W | | 0，，06： | 1 |
| 8 | Obesity prevalence from a European perspective:a systematic review显示文摘 | Pischon T Reinhold T | 2008 | Public Health2008，8，： | 1 |
| 9 | Therapy of malignant hypertension with permanent carotid sinus nerve stimulation显示文摘 | Both A Reidemeister JC Ho fer I | 1973 | Verh Dtsch Ges Inn Med1973，79，： | 1 |
| 10 | Renewable energy powered membrane technology:salt and inorganic contaminant removal by nanofiltration/reverse osmosis显示文摘 | Richards L A Richards B S Sch(a)fer A I | | 0，，1： | 1 |
| 11 | Physical and microstructuralproperties of biodegradable films based on pea starch and PVA显示文摘 | Cano A I Cháfer M Chiralt A | 2015 | Journal of Food Engineering2015，167，12： | 1 |
| 12 | The impact of NOx,CO and VOC emissions on the air quality of Zurich airport显示文摘 | Schürmann G Sch(a)fer A K Jahn C | | 0，，01： | 1 |
| 13 | Vascular ul- trasound for the pre-operative evaluation prior to ar teriovenous fistula formation for haemodialysis: re- view of the evidence显示文摘 | Ferring M Henderson J Wilmink A | 2008 | Nephrol Dial Transplant2008，23，6： | 1 |
| 14 | Adipokines and thrombosis显示文摘 | SCH(A)FER K KONSTANTINIDES S | 2011 | Clin Exp Pharmacol Physiol2011，38，12： | 1 |
| 15 | Successional changes in the genetic diversity of a marine bacterial assemblage during confinement显示文摘 | SCH(A)FER H SERVAIS P MUYZER G | 2000 | Arch Microbiol2000，173，： | 1 |
| 16 | Diffusion tensor magnetic reso-nance imaging of the breast: a pilot study显示文摘 | Bahzer PA Sch fer A DietzelM | 2011 | Eur RadiO12011，21，1： | 1 |
| 17 | Hay fever and predictive value of prick test and specific IgE antibodies:a prospective study in children显示文摘 | Sch(a)fer T Hoelscher B Adam H | 2003 | Pediatr Allergy Immunol2003，14，2： | 1 |
| 18 | Hypoxia reduces the inhibitory effect of IL-1β on chondrogenic differentiation of FCS-free expanded MSC显示文摘 | Felka T Sch(a)fer R Schewe B | 2009 | Osteoarthritis Cartilage2009，17，： | 1 |
| 19 | A highly specific system for efficient enzymatic removal of tags from recombinant proteins显示文摘 | SCH?FER F SCH?FER A STEINERT K | 2002 | J Biomol Tech2002，13，3： | 1 |
| 20 | Vascular ul- trasound for the pre-operative evaluation prior to ar teriovenous fistula formation for haemodialysis: re- view of the evidence显示文摘 | Ferring M Henderson J Wilmink A | 2008 | Nephrol Dial Trans plant2008，25，6： | 1 |
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