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您的检索式：作者名="Fidelis H A"
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| 1 | Immuno-haematologic and virologic responses and predictors of virologic failure in HIV-1 infected adults on first-line antiretroviral therapy in Cameroon显示文摘Background:Contemporary data on the immunologic,haematologic and virologic responses and predictors of virologic failure after initiation of free antiretroviral treatment in Cameroon are needed to evaluate the current treatment-monitoring algorithm and to complement efforts to scale-up and improve on the management of HIV infections.Methods:This was a cross-sectional study conducted between October 2010 and June 2012.A total of 951 participants aged 18-74 years were recruited from selected approved HIV treatment centres of the Northwest and Southwest regions.This comprised 247 males and 704 females.Demographic,self-reported risk behaviours and socioeconomic data were obtained using a structured questionnaire.Full blood and CD4+T-cell counts were done using standard automated techniques.Determination of viral load(VL)was done using Abbott RealTime HIV-1 m2000™system.Data was analysed using SPSS version 17.The statistical significance level was P<0.05.Results:The median duration of antiretroviral therapy(ART)was 24 months.The population mean CD4+T-cell count was 255.3 cells/μL[95%CI,236.8-273.9].Overall,45.9%,43.8%and 10.2%of the participants had CD4+T-cell counts of<200 cells/μL,200-499 cells/μL and>500 cells/μL respectively.Anaemia was present in 26.2%of the participants with 62.3%,25.7%and 12%described as mild,moderate and severe anaemia respectively.Virologic failure occurred in 23.2%of the participants with 12.3%having VL>10,000 RNA copies/mL.Meanwhile 76.8%of patients attained adequate viral suppression with 40.8%having undetectable viral load.The age group 18-29 years(p=0.024),co-infection with tuberculosis(p=0.014),anaemia(p=0.028)and distance from the treatment centre(p=0.011)independently predicted virologic failure.Conclusion:The majority of the participants achieved adequate viral suppression after≥6 months of ART.Despite these favourable immuno-haematologic and virologic outcomes,the National AIDS Control Program should step-up efforts to improve on antiretroviral drug distribution,as well as proper assessment and management of anaemia,foster early diagnosis and treatment of tuberculosis and enhance treatment adherence counselling especially in younger patients. | Henry D Meriki Kukwah A Tufon Mbunkah H Afegenwi Bernard A Nyindem Pascal N Atanga Damian N Anong Fidelis Cho-Ngwa Theresa Nkuo-Akenji | 2014 | Infectious Diseases of Poverty2014，3，1： | 3 |
| 2 | Surface nitriding of Ti-6A1-4V alloy with a high power CO21aser 显示文摘 | Abboud J H FidelI A F Benyounis K Y | 2008 | Optics and Laser Technology2008，40，： | 1 |
| 3 | Biologicalactivities of sulfated polysaccharides from tropical seaweeds显示文摘 | Costa L S Fidelis G P Cordeiro S L R M Oliveira D A Sabry R B G CSmara L T D B Nobre MSS PCosta J Almeida-Lima E H C Farias E L Leite H A 0 Rocha | 2010 | Biomedicine & Pharmacotherapy2010，64，1： | 1 |
| 4 | 饲料摄入量对内洛尔公牛胴体性状和肉质的影响显示文摘试验选取内洛尔公牛127头,分为低剩余饲料摄入量(RFI)和高剩余饲料摄入量,通过3个选择线和5个试验来确定RFI和胴体品质、肉品质之间的关系。对生产性能、胴体性状和背最长肌进行评估。包括RFI的固定效应、选择线、RFI等级和选择线之间的相互作用作为混合模型的主要变量,屠宰年龄作为协变量,并在试验过程中随机安排,通过T检验比较。平均饲料采食量差异为0.962 kg·d^(-1),低RFI组动物消耗量为0.479kg·d^(-1),高RFI组消耗量为0.483kg·d^(-1),高于预期水准。不同RFI组间各检测指标无差异,RFI对胴体、肉质无不利影响。低RFI可提高内洛尔公牛饲料效率和肉品质。 | Fidelis H A Bonilha S F M Tedeschi L O Branco R H Cyrillo J N S G Mercadante M E Z | 2017 | 饲料博览2017，0，8： | 0 |
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