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| 1 | 血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。 | 刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L | 2018 | 中华高血压杂志2018，26，10： | 27 |
| 2 | Tenecteplase Reperfusion therapy in Acute ischaemic Cerebrovascular Events-Ⅱ (TRACE Ⅱ): rationale and design显示文摘Background and purpose Tenecteplase(TNK)is a promising agent for treatment of acute ischaemic stroke(AIS).We hypothesised that recombinant human TNK tissue-type plasminogen activator(rhTNK-tPA)is non-inferior to rt-PA in achieving excellent functional outcome at 90 days,when administered within 4.5 hours of ischaemic stroke onset.Methods and design Tenecteplase Reperfusion therapy in Acute ischemic Cerebrovascular Events(TRACE)is a phase Ⅲ,multicentre,prospective,randomised,open-label,blinded-end point non-inferiority study.Patients eligible for intravenous thrombolysis therapy are randomised to rhTNK-tPA 0.25 mg/kg(single bolus)to a maximum of 25 mg or rt-PA 0.9 mg/kg(10%bolus+90%infusion/1 hour)to a maximum of 90 mg.Medications considered necessary for the patient’s health may be given at the discretion of the investigator during 90-day follow-up.Study outcomes The primary study outcome is excellent functional outcome defined as modified Rankin Scale(mRS)0–1 at 90 days.Secondary efficacy outcomes include favourable functional outcome defined as mRS≤2 at 90 days,ordinal distribution of mRS and major neurological improvement on the National Institutes of Health Stroke Scale.Safety outcomes are symptomatic intracranial haemorrhage within 36 hours and death from any cause.Discussion There is no completed registration study of TNK in AIS worldwide.TRACE Ⅱ strives to provide evidence for a new drug application for rhTNK-tPA in AIS within 4.5 hours through a well-designed and rigorously executed randomised trial in China. | Shuya Li Bruce C V Campbell Lee H Schwamm Marc Fisher Mark Parsons Hao Li Yuesong Pan Yongjun Wang | 2022 | Stroke & Vascular Neurology2022，7，1： | 2 |
| 3 | Occurrence of Daspartic acid and N-Methyl-D-Aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release显示文摘 | Aniello D M Fiore D Fisher G H | 2000 | FASEB J2000，14，： | 2 |
| 4 | Further insights into the no-reflow phenomenon after primary angioplasty in acute myocardial infarction:the role of microthromboemboli显示文摘 | Sakuma T Leong-Poi H Fisher NG | 2003 | J Am Soc Echocardiogr2003，16，： | 1 |
| 5 | Reducing the PAPR of multiearrier modulation by seleeted mapping显示文摘 | Bauml R W Fisher R H | 2000 | IEEE Transactions on Communication2000，32，1： | 1 |
| 6 | Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model显示文摘 | Jaeschke H Fisher MA Lawson JA | 1998 | J Immunol1998，160，7： | 1 |
| 7 | Petrology and Crystallization History of Multiphase Sulfide Droplets in a Mafic Dike from Uruguay:Implications for the Origin of Cu-Ni-PGE Sulfide Deposits显示文摘 | Prichard H M Hutchinson D Fisher P C | 2004 | Economic Geology2004，99，： | 1 |
| 8 | Reynolds stress and TKE production in an estuary with a tidal bore显示文摘 | SIMPSON J H FISHER N R WILES P | 2004 | Estuarine Coastal and Shelf Science2004，60，4： | 1 |
| 9 | Relationship of pretreatment transurethral resection of the prostate to survival without distant metastases in patients treated with ^125I-implantation for localized prostatic cancer显示文摘 | Fowler J E Jr Fisher H A Kaiser D L | 1984 | Cancer1984，53，9： | 1 |
| 10 | Knowledge acquisition via incremental conceptual clustering 显示文摘 | FISHER D H | 1987 | Machine Learning1987，2，： | 1 |
| 11 | Redox regulation of tyro- sine phosphorylation in human spermatozoa and its role in human spermatozoa and its role in human sperm function 显示文摘 | Aitken R J Paterson M Fisher H | 1995 | J Cell Sci1995，108，： | 1 |
| 12 | Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma- linolenic acid in ventilated patients with acute lung injury显示文摘 | Singer P Theilla M Fisher H | 2006 | Crit Care Med2006，34，4： | 1 |
| 13 | Mixing and dispersion in estuaries显示文摘 | FISHER H B | 1976 | Annual Review of Fluid Mechanics1976，8，： | 1 |
| 14 | Relative Consumption, Eco- nomic Growth, and Taxation 显示文摘 | Waher H Fisher Franz X Hof | 2000 | Journal of Economics2000，，3： | 1 |
| 15 | Myocardial and microcirculatory Rinetics of BR14,a nove thirdgeneration intravenous ultrasound contrast agent显示文摘 | Christiansen JP Leong-Poi H | 2002 | J Am Coll Cardiol2002，39，3： | 1 |
| 16 | Visualizing the Signatures of Social Roles in Online Discussion Groups显示文摘 | Welser H Gleave E Fisher D | 2007 | Journal of Social Structure2007，8，2： | 1 |
| 17 | Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenehymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model 显示文摘 | Jaeschke H Fisher MA Lawson JA | 1998 | J Immunol1998，160，7： | 1 |
| 18 | ELID grinding of silicon wa- fers: A literature review 显示文摘 | Liu J H Pei Z J Fisher G R | 2007 | Int J Mach Tools Manuf2007，47，34： | 1 |
| 19 | Vaccination for neuroprotection in the mouse optic nelwe:Implications for opticneuropathies显示文摘 | Fisher J Levkovitch-Verbin H Schori H | 2001 | J Neurosei2001，21，1： | 1 |
| 20 | Operative intervention in delivery is associated with compromised early mother-infant interaction显示文摘 | Rowe M H J Fisher J R | 2001 | British Journal of Obstetrics and Gynaecology2001，108，10： | 1 |
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