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| 1 | Therapy with stem cells in inflammatory bowel disease显示文摘Inflammatory bowel disease(IBD) affects a part of the young population and has a strong impact upon quality of life. The underlying etiology is not known, and the existing treatments are not curative. Furthermore, a significant percentage of patients are refractory to therapy. In recent years there have been great advances in our knowledge of stem cells and their therapeutic applications. In this context, autologous hematopoietic stem cell transplantation(HSCT) has been used in application to severe refractory Crohn's disease(CD), with encouraging results. Allogenic HSCT would correct the genetic defects of the immune system, but is currently not accepted for the treatment of IBD because of its considerable risks. Mesenchymal stem cells(MSCs) have immune regulatory and regenerative properties, and low immunogenicity(both autologous and allogenic MSCs). Based on these properties, MSCs have been used via the systemic route in IBD with promising results, though it is still too soon to draw firm conclusions. Their local administration in perianal CD is the field where most progress has been made in recent years, with encouraging results. The next few years will be decisive for defining the role of such therapy in the management of IBD. | María del Pilar Martínez-Montiel Gonzalo Jesús Gómez-Gómez Ana Isabel Flores | 2014 | World Journal of Gastroenterology2014，20，5： | 13 |
| 2 | Stem cell therapy in inflammatory bowel disease: A promising therapeutic strategy?显示文摘Inflammatory bowel diseases are inflammatory, chronic and progressive diseases of the intestinal tract for which no curative treatment is available. Research in other fields with stem cells of different sources and with immunoregulatory cells(regulatory T-lymphocytes and dendritic T-cells) opens up new expectations for their use in these diseases. The goal for stem cell-based therapy is to provide a permanent cure. To achieve this, it will be necessary to obtain a cellular product, original or genetically modified, that has a high migration capacity and homes into the intestine, has high survival after transplantation, regulates the immune reaction while not being visible to the patient's immune system, and repairs the injured tissue. | Ana I Flores Gonzalo J Gómez-Gómez ángeles Masedo-González M Pilar Martínez-Montiel | 2015 | World Journal of Stem Cells2015，7，2： | 7 |
| 3 | Thrombotic risk factors in patients with liver cirrhosis: Correlation with MELD scoring system and portal vein thrombosis development显示文摘 | Maria Assunta Zocco Enrico Di Stasio Raimondo De Cristofaro Marialuisa Novi Maria Elena Ainora Francesca Ponziani Laura Riccardi Stefano Lancellotti Angelo Santoliquido Roberto Flore Maurizio Pompili Gian Lodovico Rapaccini Paolo Tondi Giovanni Battista G | 2009 | Journal of Hepatology2009，，4： | 5 |
| 4 | Thrombotic risk factors in patients with liver cirrhosis: Correlation with MELD scoring system and portal vein thrombosis development显示文摘 | Maria Assunta Zocco Enrico Di Stasio Raimondo De Cristofaro Marialuisa Novi Maria Elena Ainora Francesca Ponziani Laura Riccardi Stefano Lancellotti Angelo Santoliquido Roberto Flore Maurizio Pompili Gian Lodovico Rapaccini Paolo Tondi Giovanni Battista G | 2009 | Journal of Hepatology2009，，4： | 2 |
| 5 | Role of serum cytokine profile in ulcerative colitis assessment显示文摘 | Manuel Luis Rodríguez‐Perlvárez Valle García‐Sánchez Carlos Manuel Villar‐Pastor Raál González Eva Iglesias‐Flores Jordi Muntane Federico Gómez‐Camacho | 2012 | Inflamm Bowel Dis2012，，10： | 2 |
| 6 | Snail is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells显示文摘 | Olmeda D Moreno-Bueno G Flores JM | 2007 | Cancer Res2007，67，11： | 1 |
| 7 | Digestion of biological materials using the microwave-assisted sample combustion technique 显示文摘 | Mesko M F Moraes D P Barin J S Dressler V L Knapp G Flores E M M | 2006 | Microchem Journal2006，82，： | 1 |
| 8 | Suppression of performance curve instability of an axial-flow pump by using a double-inlet-nozzle 显示文摘 | Perez Flores P Kosyna G Wulff D | 2008 | International Journal of Rotating Machinery2008，，53： | 1 |
| 9 | Efficacy of beta2-agonists in bronchiolitis:a reappraisal and meta-analysis显示文摘 | Flores G Horwitz RI | 1997 | Pediatrics1997，100，21： | 1 |
| 10 | Feelings of patients on the waiting list for a kidney transplant显示文摘 | Flores R V Thome E G | 2004 | Rev Bras En- ferm2004，57，6： | 1 |
| 11 | Insecticidal toxin in root exudates from Bt corn显示文摘 | SAXENA D FLORES S STOTZKY G | 1994 | Mol Ecol1994，3，： | 1 |
| 12 | Infl uence of preparation methods and Zr and Y promoters on Cu/ZnO catalysts used for methanol steam reforming显示文摘 | Sanches S G Flores J H Avillez R R D | 2012 | Int J Hydrogen Energy2012，37，8： | 1 |
| 13 | Application of microwave induced combustion in closed vessels for carbon black-containing elastomers decomposition 显示文摘 | Moraes D P Mesko M F Mello P A Paniz J N G Dressler V L Knapp G Flores E M M | 2007 | Spectrochim Acta : Part B2007，62，： | 1 |
| 14 | Capillary electrophoresis determination of methotrexate, leucovorin and folic acid in human urine显示文摘 | FLORES J R PENALVO G C MANSILLA A E | 2005 | Journal of Chromatography B2005，819，： | 1 |
| 15 | Efficacy of beta2-agonists in bronchiolitis: a reappraisal and meta-analysis显示文摘 | Flores G Horwitz RI | 1997 | Pediatrics1997，100，21： | 1 |
| 16 | 4D tropospheric tomo- graphy using GPS slant wet delays显示文摘 | Flores A Ruffini G Rius A | 2000 | Annales Geo- physicae2000，18，2： | 1 |
| 17 | Prevalence of vitamin D deficiency among overweight and obese US children 显示文摘 | Turer CB Lin H Flores G | 2013 | Pediatrics2013，131，1： | 1 |
| 18 | Assessment of chaos-based FM signals for range-Doppler imaging 显示文摘 | FLORES B C SOLIS E A THOMAS G | 2003 | IEEE Proceedings-Radar Sonar and Navigation2003，150，4： | 1 |
| 19 | Small-strain shear modulus and strength of cement-treated clay显示文摘 | FLORES RD V EMIDIO G D IMPE W F V | 2010 | Geotechnical Testing Journal2010，33，1： | 1 |
| 20 | Acrylic Bone Ce-ments Modified With Bioactive Filler显示文摘 | C F Jasso-Gastinel S G Enriquez J Flores | 2009 | Macromolecular Sym-posia2009，，： | 1 |
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