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57篇 您的检索式：作者名="Florent C"

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	题名	作者	年代	出处	被引量
1	Automatic camera calibration based on robot calibration显示文摘	MALIK M MUDAR S FLORENT C	1999	IEEE Instrumentation and Measurement Technology Conference1999，2，：	2
2	Artificial aeration to increase pollutant removal efficiency of constructed wetlands in cold climate显示文摘	CLAUDIANE O P FLORENT C YVES C	2006	Ecological Engineering2006，27，3：	1
3	Measurement of the specific surface area of 176 snow samples using methane adsorption at 77 K显示文摘	Lot'c Legagneux Axel Cabanes Florent Domine	2002	Journal of Geophysical Research2002，107，17：	1
4	Novel two-step SnOJSnO water-splitting cycle for solar ther- mochemical production of hydrogen 显示文摘	STEPHANE A PATRICE C FLORENT L	2008	International Journal of Hydrogen Energy2008，33，：	1
5	Docosa- hexaenoic acid prevents neuronal apoptosis induced by solu- ble amyloid-beta oligomers 显示文摘	Florent S Malaplate-Armand C Youssef I	2006	Neurochem2006，96，：	1
6	Theobroma cacao improves bone growth by modulating defective ciliogenesis in a mouse model of achondroplasia显示文摘A gain-of-function mutation in the fibroblast growth factor receptor 3 gene(FGFR3)results in achondroplasia(ACH),the most frequent form of dwarfism.Constitutive activation of FGFR3 impairs bone formation and elongation and many signal transduction pathways.Identification of new and relevant compounds targeting the FGFR3 signaling pathway is of broad importance for the treatment of ACH,and natural plant compounds are prime drug candidate sources.Here,we found that the phenolic compound(-)-epicatechin,isolated from Theobroma cacao,effectively inhibited FGFR3’s downstream signaling pathways.Transcriptomic analysis in an Fgfr3 mouse model showed that ciliary mRNA expression was modified and influenced significantly by the Indian hedgehog and PKA pathways.(-)-Epicatechin is able to rescue mRNA expression impairments that control both the structural organization of the primary cilium and ciliogenesis-related genes.In femurs isolated from a mouse model(Fgfr3^(Y367C/+))of ACH,we showed that(-)-epicatechin eliminated bone growth impairment during 6 days of ex vivo culture.In vivo,we confirmed that daily subcutaneous injections of(-)-epicatechin to Fgfr3^(Y367C/+) mice increased bone elongation and rescued the primary cilium defects observed in chondrocytes.This modification to the primary cilia promoted the typical columnar arrangement of flat proliferative chondrocytes and thus enhanced bone elongation.The results of the present proof-of-principle study support(-)-epicatechin as a potential drug for the treatment of ACH.	Ludovic Martin Nabil Kaci Catherine Benoist-Lasselin Marine Mondoloni Suzanne Decaudaveine Valentin Estibals Maxence Cornille Léa Loisay Justine Flipo Benoît Demuynck Maria de la Luz Cádiz-Gurrea Florent Barbault Salvador Fernández-Arroyo Laurent Schibler Antonio Segura-Carretero Emilie Dambroise Laurence Legeai-Mallet	2022	Bone Research2022，10，1：	1
7	Artificial aeration to increase pollutant removal efficiency of constructed wetlands in cold climate显示文摘	Claudiane O P Florent C Yves C	2006	Ecological Engineering2006，3，：	1
8	Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers 显示文摘	Florent S Malaplate-Armand C Youssef I	2006	J Neurochem2006，96，2：	1
9	artificial aeration to increase pollutant removal efficiency of constructed wetlands in cold climate 显示文摘	Claudiane O Florent C Yves C	2006	Ecol Eng2006，27，3：	1
10	Effect of plant species on water quality at the outlet of a sludge treatment wetland显示文摘	VINCENT G FLORENT C MARGIT K	2012	Water Research2012，46，16：	1
11	Artificial aeration to increase pollutant removal efficiency of constructed wetlands in cold climate显示文摘	Claudiane O P Florent C Yves C	2006	Ecological Engineering2006，27，：	1
12	Influence of chronic lactulose ingestion on the colonic metabolism of lactulose in man (an in vivo study) 显示文摘	Florent C Flourie B Leblond A	1985	J Clin Invest1985，75，2：	1
13	First steps of in situ surface-enhanced Raman scattering during shipboard experiments显示文摘	Olivier P Emmanuel R Florent C	2010	Applied Spectroscopy2010，64，10：	1
14	Twenty-four-hour monitoring of intragastirc acidity:comparisonbetween lansoprazole 30mg and pantoprazole 40 mg显示文摘	Florent C Formtier S	1997	Eur J Castro Hepatol1997，9，2：	1
15	Carbon Nanotube-filled Polymer Composites Numerical Simulation of Electrical Conductivity in Three-dimensional Entangled Fibrous Networks显示文摘	FLORENT D ReMY D LAURENT C	2006	Acta Materialia2006，54，11：	1
16	Targeting of antitumor drugs with monoclonal antibodies 显示文摘	Monneret C Florent J C	2013	Bull Cancer2013，87，11：	1
17	Emergency liver transplantation for acute liver failure 显示文摘	PAUWELS A MOSTEFA-KARA N FLORENT C	1993	J Hepatol1993，17，：	1
18	Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceraraide pathway显示文摘	Malaplatc Armand C Florent Bechard S		0，，01：	1
19	Images as sets of ln- cally weighted features显示文摘	TEOF1LO DE C GABRIELA C FLORENT P	2012	Computer Vision and Image Undetand- ing2012，116，1：	1
20	Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers显示文摘	Florent S Malaplate Armand C Youssef I	2006	J Neurochem2006，96，2：	1

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