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| 1 | Development of a petroleum knowledge tutorial system for university and corporate training显示文摘The increasingly rapid development of the disciplines of petroleum engineering and petroleum geology has led to new methodologies and interpretation techniques forming new knowledge that should be offered quickly and efficiently to modern engineers and geologists. This need is equally important for students as well as for young professionals. Access and training to all scientific information is necessary to ensure success in their future careers. Today, e-learning has become a common medium for the management and distribution of on-line educational content. Learning Management Systems (LMSs) were not only developed to handle a large variety of multimedia content that provides an organized knowledge repository used to accelerate access to information and skill acquisition; but, LMSs can also keep detailed statistics on the use of the available material offering a powerful training and educational tool. In this document, the Petroleum Knowledge Tutorial System, an LMS platform offering a variety of online educational and training options to petroleum engineers and geologists, is presented. It was created using Moodle, open- source software that can be used to create on-line courses. The platform covers fundamental educational concepts in a structured way. It follows an optimized 'workflow' that can be applied not only to solve a specific exercise but also any similar problem encountered over the course of one's career. The platform was designed to offer a repository of learning material in various forms and to favor user-platform interactions It can be used for training and evaluation purposes through exercises and problem solving that the user can perform online by using browsing software along with Internet access. Special tools were created and implemented on the platform to assist the user in completing a variety of tasks including performing exercises involving calculations with given data and plots of points or lines on graphs without leaving the learning environment. Furthermore, videos with detailed explanations follow each learning module and provide the full solution to every exercise. The LMS automatically keeps a large statistical database including the users' access to activities on the platform that can be exported and further processed to improve the platform functionality and evaluate the users' performance. | Verga Francesca Benetatos Christoforos Sacchi Quinto Carta Roberto | 2012 | Petroleum Science2012，9，1： | 1 |
| 2 | An Improved Treatment of Long-term Pressure Data for Capturing Information 显示文摘 | Dario Viberti Francesca Verga Paolo Delbosco | 2007 | SPE Reservoir Evaluation Engineering2007，10，4： | 1 |
| 3 | An improved treatment of long-term pressure data for capuring information显示文摘 | Dario Viberti Francesca Verga Paolo Delbosco | 2007 | SPE Reservoir Evaluation & Engineering2007，10，4： | 1 |
| 4 | Simulation of unconventional well tests with the finite volume method显示文摘The finite volume method has been successfully applied in several engineering fields and has shown outstanding performance in fluid dynamics simulation. In this paper, the general framework for the simulation of near-wellbore systems using the finite volume method is described. The mathematical model and the numerical model developed by the authors are presented and discussed. A radial geometry in the vertical plane was implemented so as to thoroughly describe near-wellbore phenomena. The model was then used to simulate injection tests in an oil reservoir through a horizontal well and proved very powerful to correctly reproduce the transient pressure behavior. The reason for this is the robustness of the method, which is independent of the gridding options because the discretization is performed in the physical space. The model is able to describe the phenomena taking place in the reservoir even in complex situations, i.e. in the presence of heterogeneities and permeability barriers, demonstrating the flexibility of the finite volume method when simulating non-conventional tests. The results are presented in comparison with those obtained with the finite difference numerical approach and with analytical methods, if possible. | CANCELLIERE Michel VERGA Francesca | 2012 | Petroleum Science2012，9，3： | 1 |
| 5 | Liver-side of inflammatory bowel diseases:Hepatobiliary and druginduced disorders显示文摘Hepatobiliary disorders are among the most common extraintestinal manifestations in inflammatory bowel diseases(IBD),both in Crohn’s disease and ulcerative colitis(UC),and therefore represent a diagnostic challenge.Immunemediated conditions include primary sclerosing cholangitis(PSC)as the main form,variant forms of PSC(namely small-duct PSC,PSC-autoimmune hepatitis overlap syndrome and IgG4-related sclerosing cholangitis)and granulomatous hepatitis.PSC is by far the most common,presenting in up to 8%of IBD patients,more frequently in UC.Several genetic foci have been identified,but environmental factors are preponderant on disease pathogenesis.The course of the two diseases is typically independent.PSC diagnosis is based mostly on typical radiological findings and exclusion of secondary cholangiopathies.Risk of cholangiocarcinoma is significantly increased in PSC,as well as the risk of colorectal cancer in patients with PSC and IBD-related colitis.No disease-modifying drugs are approved to date.Thus,PSC management is directed against symptoms and complications and includes medical therapies for pruritus,endoscopic treatment of biliary stenosis and liver transplant for end-stage liver disease.Other nonimmune-mediated hepatobiliary disorders are gallstone disease,whose incidence is higher in IBD and reported in up to one third of IBD patients,non-alcoholic fatty liver disease,pyogenic liver abscess and portal vein thrombosis.Druginduced liver injury(DILI)is an important issue in IBD,since most IBD therapies may cause liver toxicity;however,the incidence of serious adverse events is low.Thiopurines and methotrexate are the most associated with DILI,while the risk related to anti-tumor necrosis factor-αand anti-integrins is low.Data on hepatotoxicity of newer drugs approved for IBD,like anti-interleukin 12/23 and tofacitinib,are still scarce,but the evidence from other rheumatic diseases is reassuring.Hepatitis B reactivation during immunosuppressive therapy is a major concern in IBD,and adequate screening and vaccination is warranted.On the other hand,hepatitis C reactivation does not seem to be a real risk,and hepatitis C antiviral treatment does not influence IBD natural history.The approach to an IBD patient with abnormal liver function tests is complex due to the wide range of differential diagnosis,but it is of paramount importance to make a quick and accurate diagnosis,as it may influence the therapeutic management. | Stefano Mazza Sara Soro Maria Chiara Verga Biagio Elvo Francesca Ferretti Fabrizio Cereatti Andrea Drago Roberto Grassia | 2021 | World Journal of Hepatology2021，13，12： | 1 |
| 6 | Anxiety and depression in COPD patients: The roles of gender and disease severity显示文摘 | Fabiano Di Marco Massimo Verga Manuela Reggente Francesca Maria Casanova Pierachille Santus Francesco Blasi Luigi Allegra Stefano Centanni | 2006 | Respiratory Medicine2006，，10： | 1 |
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