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| 1 | Monitoring earthquakes with gravity meters显示文摘Seismic waves from a magnitude 8.3 earthquake in Japan were consistently recorded by five nearly identical gPhone gravity meters in Colorado. Good correlation was also found in the response of two different types of gravity meters and a standard seismometer in Walferdange, Luxembourg to an earthquake of magnitude 8.2 in Japan, indicating that all of them were capable of measuring the surface waves reliably. The gravity meters, however, recorded 11 separate arrivals of Raleigh waves, while the seismometer only one. Thus the gravity meters may be useful for obtaining new information in the study of seismic velocities, attenuation and dispersion. | T.M. Niebauer Jeff MacQueen Daniel Aliod Olivier Franci | 2011 | Geodesy and Geodynamics2011，2，3： | 10 |
| 2 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008，，5： | 8 |
| 3 | Juvenile polyposis syndrome显示文摘Juvenile polyposis syndrome is a rare autosomal dominant syndrome characterized by multiple distinct juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer.The cumulative life-time risk of colorectal cancer is 39% and the relative risk is 34.Juvenile polyps have a distinctive histology characterized by an abundance of edematous lamina propria with inflammatory cells and cystically dilated glands lined by cuboidal to columnar epithelium with reactive changes.Clinically,juvenile polyposis syndrome is defined by the presence of 5 or more juvenile polyps in the colorectum,juvenile polyps throughout the gastrointestinal tract or any number of juvenile polyps and a positive family history of juvenile polyposis.In about 50%-60% of patients diagnosed with juvenile polyposis syndrome a germline mutation in the SMAD4 or BMPR1A gene is found.Both genes play a role in the BMP/TGF-beta signalling pathway.It has been suggested that cancer in juvenile polyposis may develop through the socalled 'landscaper mechanism' where an abnormal stromal environment leads to neoplastic transformation of the adjacent epithelium and in the end invasive carcinoma.Recognition of this rare disorder is important for patients and their families with regard to treatment,follow-up and screening of at risk individuals.Each clinician confronted with the diagnosis of a juvenile polyp should therefore consider the possibility of juvenile polyposis syndrome.In addition,juvenile polyposis syndrome provides a unique model to study colorectal cancer pathogenesis in general and gives insight in the molecular genetic basis of cancer.This review discusses clinical manifestations,genetics,pathogenesis and management of juvenile polyposis syndrome. | Lodewijk AA Brosens Danielle Langeveld W Arnout van Hattem Francis M Giardiello G Johan A Offerhaus | 2011 | World Journal of Gastroenterology2011，17，44： | 7 |
| 4 | Symptom management during and after treatment with concurrent chemoradiotherapy for oropharyngeal cancer:A review of the literature and areas for future research显示文摘Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatmentrelated toxicity.Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and disfiguring surgery,treatment related toxicities are often difficult to control.Acute toxicities include mucositis,skin desquamation,depression,cachexia,fatigue and nausea and vomiting.Failure to control these symptoms can adversely affect the patient's ability to complete their treatment regimen.Although there are many promising new treatments in the area of symptom management for this patient population,a review of the literature reflects the need for more research. | Heidi Mason Mary Beth De Rubeis Nancy Burke Melissa Shannon Danielle Karsies Gregory Wolf Avi Eisbruch Francis Worden | 2016 | World Journal of Clinical Oncology2016，7，2： | 5 |
| 5 | A multi‐institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer显示文摘 | Edward J. Kim Edgar Ben‐Josef Joseph M. Herman Tanios Bekaii‐Saab Laura A. Dawson Kent A. Griffith Isaac R. Francis Joel K. Greenson Diane M. Simeone Theodore S. Lawrence Daniel Laheru Christopher L. Wolfgang Terence Williams Mark Bloomston Malcolm J. Moo | 2013 | Cancer2013，，15： | 3 |
| 6 | A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection显示文摘 | Jean–Charles Nault Aurélien De Reyniès Augusto Villanueva Julien Calderaro Sandra Rebouissou Gabrielle Couchy Thomas Decaens Dominique Franco Sandrine Imbeaud Francis Rousseau Daniel Azoulay Jean Saric Jean–Frédéric Blanc Charles Balabaud Paulette Bioulac | 2013 | Gastroenterology2013，，1： | 3 |
| 7 | Tumor Progression While on Chemotherapy: A Contraindication to Liver Resection for Multiple Colorectal Metastases?显示文摘 | René Adam Gerard Pascal Denis Castaing Daniel Azoulay Valerie Delvart Bernard Paule Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，6： | 2 |
| 8 | Imaging of retroperitoneal ganglioneuroma显示文摘 | Philippe Otal Sana Mezghani Sala Hassissene Geert Maleux Daniel Colombier Hervé Rousseau Francis Joffre | 2001 | European Radiology2001，，6： | 2 |
| 9 | No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting显示文摘 | Francis Jacob Mara Meier Rosmarie Caduff Darlene Goldstein Tatiana Pochechueva Neville Hacker Daniel Fink Viola Heinzelmann-Schwarz | 2011 | Gynecologic Oncology2011，，3： | 2 |
| 10 | Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy: A Model to Predict Long-term Survival显示文摘 | René Adam Valérie Delvart Gérard Pascal Adrian Valeanu Denis Castaing Daniel Azoulay Sylvie Giacchetti Bernard Paule Francis Kunstlinger Odile Ghémard Francis Levi Henri Bismuth | 2004 | Annals of Surgery2004，，4： | 2 |
| 11 | Tumor Marker Evolution: Comparison with Imaging for Assessment of Response to Chemotherapy in Patients with Colorectal Liver Metastases显示文摘 | Robbert J. Haas Dennis A. Wicherts Eduardo Flores Michel Ducreux Francis Lévi Bernard Paule Daniel Azoulay Denis Castaing Antoinette Lemoine René Adam | 2010 | Annals of Surgical Oncology2010，，4： | 2 |
| 12 | Nutritional aspects of chronic obstructive pulmonary disease显示文摘 | Daniel AK Francis C Steven MS | 2008 | Proc Am Thorac Soc2008，5，： | 1 |
| 13 | New concept in the treatment of Ureteral calculi显示文摘 | Daniel J Painter Francis X | 2001 | Curt Opin urol2001，，11： | 1 |
| 14 | Nutritional aspects of chronic obstructive pulmonary disease显示文摘 | Daniel AK Francis C Steven MS | 2008 | Proc Am Thorac Soc2008，5，： | 1 |
| 15 | Bietti Crystalline Corneoretinal Dystrophy Is Caused by Mutations in the Novel Gene CYP4V2显示文摘 | Anren Li Xiaodong Jiao Francis L. Munier Daniel F. Schorderet Wenliang Yao Fumino Iwata Mutsuko Hayakawa Atsushi Kanai Muh Shy Chen Richard Alan Lewis John Heckenlively Richard G. Weleber Elias I. Traboulsi Qingjiong Zhang Xueshan Xiao Muriel Kaiser-Kupfe | 2004 | The American Journal of Human Genetics2004，，5： | 1 |
| 16 | Changes in stiffness induced by hindlimb suspension in rat Achilles tendon显示文摘 | Maria Izabel Almeida-Silveira Daniel Lambertz Chantal Pérot Francis Goubel | 2000 | European Journal of Applied Physiology2000，，3： | 1 |
| 17 | Genetic Linkage of Bietti Crystallin Corneoretinal Dystrophy to Chromosome 4q35显示文摘 | Xiaodong Jiao Francis L. Munier Fumino Iwata Mutsuko Hayakawa Atsushi Kanai June Lee Daniel F. Schorderet Muh-Shy Chen Muriel Kaiser-Kupfer J. Fielding Hejtmancik | 2000 | The American Journal of Human Genetics2000，，5： | 1 |
| 18 | DNA methylating and demethylating treatments modify phenotype and cell wall differentiation state in sugarbeet cell lines显示文摘 | Adisa Causevic Alain Delaunay Sa?da Ounnar Michel Righezza Francis Delmotte Franck Brignolas Daniel Hagège Stéphane Maury | 2005 | Plant Physiology and Biochemistry2005，，7： | 1 |
| 19 | Genetic Evidence of Middle East Respiratory Syndrome Coronavirus(MERS-Cov) and Widespread Seroprevalence among Camels in Kenya显示文摘We describe the first genome isolation of Middle East respiratory syndrome coronavirus(MERS-CoV) in Kenya. This fatal zoonotic pathogen was first described in the Kingdom of Saudi Arabia in 2012. Epidemiological and molecular evidence revealed zoonotic transmission from camels to humans and between humans. Currently, MERS-CoV is classified by the WHO as having high pandemic potential requiring greater surveillance. Previous studies of MERS-CoV in Kenya mainly focused on site-specific and archived camel and human serum samples for antibodies. We conducted active nationwide cross-sectional surveillance of camels and humans in Kenya, targeting both nasal swabs and plasma samples from 1,163 camels and 486 humans collected from January 2016 to June 2018. A total of 792 camel plasma samples were positive by ELISA. Seroprevalence increased with age, and the highest prevalence was observed in adult camels(82.37%, 95%confidence interval(CI) 79.50–84.91). More female camels were significantly seropositive(74.28%, 95% CI 71.14–77.19)than male camels(P \ 0.001)(53.74%, 95% CI 48.48–58.90). Only 11 camel nasal swabs were positive for MERS-CoV by reverse transcription-quantitative PCR. Phylogenetic analysis of whole genome sequences showed that Kenyan MERSCoV clustered within sub-clade C2, which is associated with the African clade, but did not contain signature deletions of orf4 b in African viruses. None of the human plasma screened contained neutralizing antibodies against MERS-CoV. This study confirms the geographically widespread occurrence of MERS-CoV in Kenyan camels. Further one-health surveillance approaches in camels, wildlife, and human populations are needed. | Sheila Ommeh Wei Zhang Ali Zohaib Jing Chen Huajun Zhang Ben Hu Xing-Yi Ge Xing-Lou Yang Moses Masika Vincent Obanda Yun Luo Shan Li Cecilia Waruhiu Bei Li Yan Zhu Desterio Ouma Vincent Odendo Lin-Fa Wang Danielle E.Anderson Jacqueline Lichoti Erick Mungube Francis Gakuya Peng Zhou Kisa-Juma Ngeiywa Bing Yan Bernard Agwanda Zheng-Li Shi | 2018 | Virologica Sinica2018，33，6： | 1 |
| 20 | Poor sleep quality predicts onset of either major depression or subsyndromal depression with irritability during interferon-alpha treatment显示文摘 | Peter L. Franzen Daniel J. Buysse Mordechai Rabinovitz Bruce G. Pollock Francis E. Lotrich | 2009 | Psychiatry Research2009，，1： | 1 |
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