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6篇 您的检索式:作者名="Franco Aversa"
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1Optimal management of a patient with recurrent nasopharyngeal carcinoma显示文摘Nasopharyngeal carcinoma is rare in western countries, accounting for less than 1% of all malignancies. Despite prognosis is satisfactory for newly diagnosed, non-metastatic disease, management of recurrent disease is challenging, with a survival expectancy of approximately 6 mo with the use of chemotherapy as the sole salvage treatment. We report a case of recurrent nasopharyngeal carcinoma treated with a combination of chemotherapy, radiotherapy and surgery in the context of a multidisciplinary approach. A durable complete response was achieved.Francesco Perri Italo Dell’Oca Paolo Muto Concetta Schiavone Corrado Aversa Franco Fulciniti Raffaele Solla Giuseppina Della Vittoria Scarpati Carlo Buonerba Giuseppe Di Lorenzo Francesco Caponigro 2014World Journal of Clinical Cases2014,2,7:8
2Photodynamic purging of alloreactive T cells for adoptive immunotherapy after haploidentical stem cell transplantation显示文摘Katia Perruccio Fabiana Topini Antonella Tosti Alessandra Carotti Teresa Aloisi Franco Aversa Massimo F. Martelli Andrea Velardi 2007Blood Cells Molecules and Diseases2007,,1:1
3Prospects for dendritic cell vaccination against fungal infections in hematopoietic transplantation显示文摘Katia Perruccio Silvia Bozza Claudia Montagnoli Silvia Bellocchio Franco Aversa Massimo Martelli Francesco Bistoni Andrea Velardi Luigina Romani 2004Blood Cells, Molecules and Diseases2004,,:1
4The haploidentical option for high-risk haematological malignancies显示文摘Franco Aversa Yair Reisner Massimo F. Martelli 2007Blood Cells Molecules and Diseases2007,,1:1
5Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO显示文摘Innate responses combine with adaptive immunity to generate the most effective form of anti-Aspergillus immune resistance.Whereas the pivotal role of dendritic cells in determining the balance between immunopathology and protective immunity to the fungus is well established,we determined that epithelial cells(ECs)also contributes to this balance.Mechanistically,EC-mediated protection occurred through a Toll-like receptor 3/Toll/IL-1 receptor domain-containing adaptor-inducing interferon(TLR3/TRIF)-dependent pathway converging on indoleamine 2,3-dioxygenase(IDO)via non-canonical nuclear factor-kB activation.Consistent with the high susceptibility of TRIF-deficient mice to pulmonary aspergillosis,bone marrow chimeric mice with TRIF unresponsive ECs exhibited higher fungal burdens and inflammatory pathology than control mice,underexpressed the IDO-dependent T helper 1/regulatory T cell(Th1/Treg)pathway and overexpressed the Th17 pathway with massive neutrophilic inflammation in the lungs.Further studies with interferon(IFN)-c,IDO or IL-17R unresponsive cells confirmed the dependency of immune tolerance to the fungus on the IFN-c/IDO/Treg pathway and of immune resistance on the MyD88 pathway controlling the fungal growth.Thus,distinct immune pathways contribute to resistance and tolerance to the fungus,to which the hematopoietic/non-hematopoietic compartments contribute through distinct,yet complementary,roles.Antonella de Luca Silvia Bozza Teresa Zelante Silvia Zagarella Carmen D’Angelo Katia Perruccio Carmine Vacca Agostinho Carvalho Cristina Cunha Franco Aversa Luigina Romani 2010Cellular & Molecular Immunology2010,7,6:1
6Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation显示文摘Mauro Di Ianni Franca Falzetti Alessandra Carotti Adelmo Terenzi Beatrice Del Papa Katia Perruccio Loredana Ruggeri Paolo Sportoletti Emanuela Rosati Pierfrancesco Marconi Brunangelo Falini Yair Reisner Andrea Velardi Franco Aversa Massimo F. Martelli 2011Best Practice & Research Clinical Haematology2011,,3:1
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