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| 1 | Effect of low molecular weight heparin (enoxaparin) on congenital cataract surgery显示文摘AIM: To assess the efficacy of intracameral enoxaparin (a low-molecular-weight heparin) infusion, in variable doses on postoperative inflammatory response in congenital cataract surgery.METHODS: It is a prospective, randomized controlled trial. Eighty eyes of 53 children with congenital cataract were enrolled in this study. Every eye had primary posterior capsulorrhexis and intraocular lens (IOL) implantation after lens aspiration. The eyes were divided into 4 equal groups. In group 1 balanced salt solution (BSS) without enoxaparin was used as an irrigation solution. Whereas in group 2, 3 and 4, 40mg, 20mg and 10mg enoxaparin in 500mL BSS was used respectively. The inflammatory response in the anterior chamber was compared among the groups with slit-lamp biomicroscopy.RESULTS: The mean follow-up period was (17.75±3.95) months in group 1, (18.00±5.15) months in group 2, (19.20±5.47) months in group 3 and (18.65±5.16) months in group 4. Mean number of inflammatory cells in the anterior chamber in group 1 was significantly higher than that of group 2, 3, 4 (P<0.001). There was fibrin formation in the anterior chambers of 3 eyes in group 1 and one eye in group 4. There was synechiae formation in 3 eyes of group 1 and one eye of group 4. There was no significant difference among the groups by means of fibrin or synechiae formation (P>0.05). There were IOL precipitates in 4 eyes of group 1 and 2 eyes of group 4. IOL precipitate formation was significantly higher in group 1 than that of group 2 and 3 in which there was no IOL precipitate (P=0.048). There was IOL subluxation in only one eye of group 1, 3 and 4 while no subluxation was observed in group 2 (P>0.05). There was no statistically significant difference detected about IOL subluxation occurance in all 4 groups (P>0.05). CONCLUSION: Complications of cataract surgery in congenital cataract patients associated with postoperative inflammatory response found to be decreased with the use of enoxaparin in intraocular infusion solutions. Furthermore according to our results the anti-inflammatory effect of enoxaparin was dose dependant. | Ihsan aa Alparslan Sahin Abdullah Kürsat Cingü Seyhmus Ari Fuat Alakus Yasin inar | 2012 | International Journal of Ophthalmology(English edition)2012，5，5： | 3 |
| 2 | Single injection of triamcinolone versus three repeated injections of bevacizumab for treatment of diabetic macular edema显示文摘 | Mehmet Ta? Veysi ?ner Mehmet Fuat Alaku? Fatih Mehmet Türkcü Yal??n ??can Kemal Yüksel | 2013 | International Ophthalmology2013，，4： | 1 |
| 3 | Investigation of corneal topographic and densitometric properties of Wilson's disease patients with or without a Kayser-Fleischer显示文摘Background:To investigate the topographic measurements and densitometry of corneas in Wilson's disease(WD)patients with or without a Kayser-Fleischer ring(KF-r)compared to healthy individuals.Methods:This cross-sectional study included 20 WD patients without a KF-r(group I),18 WD patients with a KF-r(groupⅠ),and 20 age-matched controls(group Ⅱ).The Pentacam high-resolution imaging system is used to determine corneal topographic measurements and densitometry.Results:Mean age for groups Ⅰ,Ⅱ and Ⅲ was 25.40±6.43 years(14-36 years),25.38±6.96 years(16-39 years),and 23.60±6.56 years(17-35 years),respectively(P=0.623).There was no significant difference between the groups in terms of the anterior corneal densitometry values(P>0.05),while the 6-10 mm and 10-12 mm midstroma and the 2-6 mm,6-10 mm,and 10-12 mm posterior corneal densitometry values in group Ⅱ were significantly higher than those in groups Ⅰ and Ⅱ(for all values,P<0.05).However,the 10-12 mm posterior corneal densitometry values in group Ⅰ were also significantly higher than those in group Ⅲ(P=0.038).The central corneal thickness(CCT),thinnest corneal thickness(tCT),and corneal volume(CV)values in groups Ⅰ and Ⅱ were significantly lower than those in group Ⅱ(for CCT values,P=0.011 and P=0.009;for tCT values,P=0.010 and P=0.005;for CV values,P=0.043 and P=0.029).Conclusion:In WD patients with a KF-r,corneal transparency decreased in the peripheral posterior and midstromal corneal layers;for these patients,corneal transparency may be impaired not only in the peripheral cornea but also in the paracentral cornea. | Mehmet Fuat Alakus Mehtap Caglayan Nazim Ekin Hasan Oncul Esref Arac Umut Dag Halit Diri | 2023 | Eye and Vision2023，9，2： | 0 |
| 4 | Investigation of corneal topographic and densitometric properties of Wilson's disease patients with or without a Kayser-Fleischer ring显示文摘Background:To investigate the topographic measurements and densitometry of corneas in Wilson’s disease(WD)patients with or without a Kayser-Fleischer ring(KF-r)compared to healthy individuals.Methods:This cross-sectional study included 20 WD patients without a KF-r(group I),18 WD patients with a KF-r(group II),and 20 age-matched controls(group III).The Pentacam high resolution imaging system is used to determine corneal topographic measurements and densitometry.Results:Mean age for groups I,II and III was 25.40±6.43 years(14-36 years),25.38±6.96 years(16-39 years),23.60±6.56 years(17-35 years),respectively(P=0.623).There was no significant difference between the groups in terms of the anterior corneal densitometry values(P>0.05),while the 6-10mm and 10-12 mm mid stroma and the 2-6 mm,6-10 mm,and 10-12 mm posterior corneal densitometry values in group II were significantly higher than those in groups I and III(for all values,P<0.05).However,the 10-12mm posterior corneal densitometry values in group I were also significantly higher than those in group III(P=0.038).The central corneal thickness(CCT),thinnest corneal thickness(tCT),and corneal volume(CV)values in groups I and II were significantly lower than those in group III(for CCT values,P=0.011 and P=0.009;for tCT values,P=0.010 and P=0.005;for CV values,P=0.043 and P=0.029).Conclusion:In WD patients with a KF-r,corneal transparency decreased in the peripheral posterior and mid stromal corneal layers;for these patients,corneal transparency may be impaired not only in the peripheral cornea but also in the paracentral cornea. | Mehmet Fuat Alakus Mehtap Caglayan Nazım Ekin Hasan Oncul Esref Arac Umut Dag Halit Diri | 2021 | Eye and Vision2021，8，1： | 0 |
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