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| 1 | Waveband Selection with Equivalent Prediction Performance for FTIR/ATR Spectroscopic Analysis of COD in Sugar Refinery Waste Water显示文摘The level of chemical oxygen demand(COD)is an important index to evaluate whether sewage meets the discharge requirements,so corresponding tests should be carried out before discharge.Fourier transform infrared spectroscopy(FTIR)and attenuated total reflectance(ATR)can detect COD in sewage effectively,which has advantages over conventional chemical analysis methods.And the selection of characteristic bands was one of the key links in the application of FTIR/ATR spectroscopy.In this work,based on the moving window partial least-squares(MWPLS)regression to select a characteristic wavelength,a method of equivalent wavelength selection was proposed combining with paired t-test equivalent concept.The results showed that the prediction effect of the selected wavelength was very close to that of the MWPLS method,while the number of wavelength points was much smaller.SEPAve,RP,Ave,SEPStd,and RP,Std which characterized the modeling effect were 26.3 mg L^-1,0.969,3.49 mg L^-1,and 0.006,respectively.The validation effect V-SEP and V-RP were 28.64 mg L^-1 and 0.960,respectively.The selected waveband was between 1809 cm^-1 and 1568 cm^-1.The method was of more reference value for the design of FTIR/ATR spectral instrument for COD detection. | Jun Xie Dapeng Sun Jiaxiang Cai Fuhong Cai | 2019 | Computers, Materials & Continua2019，，5： | 1 |
| 2 | Effect of Human Umbilical Cord Mesenchymal Stem Cells on GRP78/ATF4 Pathway in Alzheimer s Disease Model Mice显示文摘[Objectives]To study the effect of human umbilical cord mesenchymal stem cells(hUC-MSCs)on GRP78/ATF4 pathway in APP/PS1 mice.[Methods]Twelve 6-month-old female APP/PS1 mice were randomly divided into model group(MOD,n=6)and human umbilical cord mesenchymal stem cell treatment group(MSC,n=6);six 6-month-old C57BL/6N mice were used as control group(CON,n=6).The mice in each group were treated with the fourth generation of human umbilical cord mesenchymal stem cells through tail vein.Four weeks later,the mice in each group were killed.The expression of GFP78 and ATF4 in the cortex of mice in each group was detected by Western blotting and real-time fluorescence quantitative PCR.[Results]The results of immunoblotting and real-time fluorescence quantitative PCR showed that the expression of GRP78 in MOD group was lower than that in CON group and the expression of ATF4 increased.The expression of GRP78 protein in MSC group was higher than that in MOD group,but the expression of ATF4 protein was lower.The results of real-time fluorescence quantitative PCR showed that the mRNA level of GRP78 decreased and the mRNA level of ATF4 increased in MOD group compared with CON group.The mRNA level of GRP78 in MSC group was higher than that in MOD group,while the mRNA level of ATF4 in MSC group was lower than that in MOD group.[Conclusions]Human umbilical cord mesenchymal stem cells can regulate the expression of GRP78/ATF4 pathway in APP/PSI mice,which may be related to the stress level of endoplasmic reticulum in the brain of APP/PS1 mice mediated by human umbilical cord mesenchymal stem cells. | Fuhong LI Tianyu WANG Junjie CAI Zhuorui HE Yufan ZANG Liqun REN | 2023 | Medicinal Plant2023，14，6： | 0 |
| 3 | Band Selection Method of Absorption Peak Perturbance for the FTIR/ATR SpectrumAnalysis显示文摘The rapid quantification method of human serum glucose was established by using the Fourier transform infrared spectroscopy(FTIR)and attenuated total reflection(ATR).By the subtracted spectra between glucose aqueous solution and de-ionized water,absorption peaks are calculated in fingerprint area.Based on these absorption peaks and multiple linear regression(MLR)model,discrete band selection method of absorption peaks disturbance model(APDM)was developed.5 absorption peaks 1150 cm^-1,1103 cm^-1,1078 cm^-1,1034 cm^-1,991 cm^-1 were found in fingerprint area.Used these absorption peaks to establish absorption peaks disturbance model,the optimal wavelength combinations are 1140 cm^-1,1096 cm^-1,1084 cm^-1,1030 cm^-1,993 cm^-1,the corresponding C-RMSEP and C-RP are 1.164 mmol/L and 0.828 respectively.The results show that the optimal prediction effect of APDM was obviously better than the one of the Partial least squares(PLS)model,and the complexity of the optimal model is reduced greatly also.The results also provide a theoretical basis for design of small and portable human serum glucose spectrometer. | Jun Xie Chong Wang Jiaxiang Cai Fuhong Cai | 2018 | Computers, Materials & Continua2018，，11： | 0 |
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